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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
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1999 4
2000 10
2001 5
2002 11
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2005 5
2006 6
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Page 1
Discovery and SAR of potent, orally available and brain-penetrable 5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen- and 4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulen derivatives as neuropeptide Y Y5 receptor antagonists.
Rueeger H, Gerspacher M, Buehlmayer P, Rigollier P, Yamaguchi Y, Schmidlin T, Whitebread S, Nuesslein-Hildesheim B, Nick H, Cricione L. Rueeger H, et al. Bioorg Med Chem Lett. 2004 May 17;14(10):2451-7. doi: 10.1016/j.bmcl.2004.03.014. Bioorg Med Chem Lett. 2004. PMID: 15109631
Design, syntheses, and structure-activity relationships of novel NPY Y5 receptor antagonists: 2-{3-Oxospiro[isobenzofuran-1(3H),4'-piperidin]-1'-yl}benzimidazole derivatives.
Ogino Y, Ohtake N, Nagae Y, Matsuda K, Moriya M, Suga T, Ishikawa M, Kanesaka M, Mitobe Y, Ito J, Kanno T, Ishihara A, Iwaasa H, Ohe T, Kanatani A, Fukami T. Ogino Y, et al. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5010-4. doi: 10.1016/j.bmcl.2008.08.018. Epub 2008 Aug 12. Bioorg Med Chem Lett. 2008. PMID: 18723347
Aryl urea derivatives of spiropiperidines as NPY Y5 receptor antagonists.
Takahashi T, Haga Y, Sakamoto T, Moriya M, Okamoto O, Nonoshita K, Shibata T, Suga T, Takahashi H, Hirohashi T, Sakuraba A, Gomori A, Iwaasa H, Ohe T, Ishihara A, Ishii Y, Kanatani A, Fukami T. Takahashi T, et al. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3511-6. doi: 10.1016/j.bmcl.2009.05.013. Epub 2009 May 9. Bioorg Med Chem Lett. 2009. PMID: 19464889
98 results