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Items: 1 to 20 of 102

1.

Tracazolate reveals a novel type of allosteric interaction with recombinant gamma-aminobutyric acid(A) receptors.

Thompson SA, Wingrove PB, Connelly L, Whiting PJ, Wafford KA.

Mol Pharmacol. 2002 Apr;61(4):861-9.

2.

alpha1beta2delta, a silent GABAA receptor: recruitment by tracazolate and neurosteroids.

Zheleznova N, Sedelnikova A, Weiss DS.

Br J Pharmacol. 2008 Mar;153(5):1062-71. doi: 10.1038/sj.bjp.0707665.

3.

Interaction of H+ and Zn2+ on recombinant and native rat neuronal GABAA receptors.

Krishek BJ, Moss SJ, Smart TG.

J Physiol. 1998 Mar 15;507 ( Pt 3):639-52.

4.
6.

Subunit-selective modulation of GABAA receptors by the non-steroidal anti-inflammatory agent, mefenamic acid.

Halliwell RF, Thomas P, Patten D, James CH, Martinez-Torres A, Miledi R, Smart TG.

Eur J Neurosci. 1999 Aug;11(8):2897-905.

PMID:
10457186
7.

3-Hydroxy-2'-methoxy-6-methylflavone: a potent anxiolytic with a unique selectivity profile at GABA(A) receptor subtypes.

Karim N, Gavande N, Wellendorph P, Johnston GA, Hanrahan JR, Chebib M.

Biochem Pharmacol. 2011 Dec 15;82(12):1971-83. doi: 10.1016/j.bcp.2011.09.002.

PMID:
21924247
8.

Enhancement of benzodiazepine and GABA binding by the novel anxiolytic, tracazolate.

Meiners BA, Salama AI.

Eur J Pharmacol. 1982 Mar 12;78(3):315-22.

PMID:
6121710
9.

Pharmacology of pyrazolopyridines.

Patel JB, Malick JB, Salama AI, Goldberg ME.

Pharmacol Biochem Behav. 1985 Oct;23(4):675-80. Review.

PMID:
2866547
10.
11.

Functional comparison of the role of gamma subunits in recombinant human gamma-aminobutyric acidA/benzodiazepine receptors.

Wafford KA, Bain CJ, Whiting PJ, Kemp JA.

Mol Pharmacol. 1993 Aug;44(2):437-42.

PMID:
8102787
12.

The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors.

Popik P, Kostakis E, Krawczyk M, Nowak G, Szewczyk B, Krieter P, Chen Z, Russek SJ, Gibbs TT, Farb DH, Skolnick P, Lippa AS, Basile AS.

J Pharmacol Exp Ther. 2006 Dec;319(3):1244-52.

15.

Estimating the efficiency of benzodiazepines on GABA(A) receptors comprising gamma1 or gamma2 subunits.

Baburin I, Khom S, Timin E, Hohaus A, Sieghart W, Hering S.

Br J Pharmacol. 2008 Oct;155(3):424-33. doi: 10.1038/bjp.2008.271.

16.

Effect of alpha subunit on allosteric modulation of ion channel function in stably expressed human recombinant gamma-aminobutyric acid(A) receptors determined using (36)Cl ion flux.

Smith AJ, Alder L, Silk J, Adkins C, Fletcher AE, Scales T, Kerby J, Marshall G, Wafford KA, McKernan RM, Atack JR.

Mol Pharmacol. 2001 May;59(5):1108-18.

17.

Etomidate produces similar allosteric modulation in α1β3δ and α1β3γ2L GABA(A) receptors.

Feng HJ, Jounaidi Y, Haburcak M, Yang X, Forman SA.

Br J Pharmacol. 2014 Feb;171(3):789-98. doi: 10.1111/bph.12507.

19.

The interactions of hexachlorocyclohexane isomers with human gamma-aminobutyric acid(A) receptors expressed in Xenopus oocytes.

Aspinwall LS, Bermudez I, King LA, Wafford KA.

J Pharmacol Exp Ther. 1997 Sep;282(3):1557-64.

20.

Functional characteristics of recombinant human GABA(A) receptors containing the epsilon-subunit.

Thompson SA, Bonnert TP, Whiting PJ, Wafford KA.

Toxicol Lett. 1998 Nov 23;100-101:233-8.

PMID:
10049148
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