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Methylation patterns of the human beta-glucuronidase gene locus: boundaries of methylation and general implications for frequent point mutations at CpG dinucleotides.

Tomatsu S, Orii KO, Islam MR, Shah GN, Grubb JH, Sukegawa K, Suzuki Y, Orii T, Kondo N, Sly WS. Tomatsu S, et al. Genomics. 2002 Mar;79(3):363-75. doi: 10.1006/geno.2002.6706. Genomics. 2002. PMID: 11863366

General implications for CpG hot spot mutations: methylation patterns of the human iduronate-2-sulfatase gene locus.

Tomatsu S, Orii KO, Bi Y, Gutierrez MA, Nishioka T, Yamaguchi S, Kondo N, Orii T, Noguchi A, Sly WS. Tomatsu S, et al. Hum Mutat. 2004 Jun;23(6):590-8. doi: 10.1002/humu.20046. Hum Mutat. 2004. PMID: 15146464

Differences in methylation patterns in the methylation boundary region of IDS gene in Hunter syndrome patients: implications for CpG hot spot mutations.

Tomatsu S, Sukegawa K, Trandafirescu GG, Gutierrez MA, Nishioka T, Yamaguchi S, Orii T, Froissart R, Maire I, Chabas A, Cooper A, Di Natale P, Gal A, Noguchi A, Sly WS. Tomatsu S, et al. Eur J Hum Genet. 2006 Jul;14(7):838-45. doi: 10.1038/sj.ejhg.5201615. Epub 2006 Apr 12. Eur J Hum Genet. 2006. PMID: 16617305

The 5'-end transitional CpGs between the CpG islands and retroelements are hypomethylated in association with loss of heterozygosity in gastric cancers.

Kim YH, Hong SJ, Jung YC, Kim SJ, Seo EJ, Choi SW, Rhyu MG. Kim YH, et al. BMC Cancer. 2006 Jul 10;6:180. doi: 10.1186/1471-2407-6-180. BMC Cancer. 2006. PMID: 16827945 Free PMC article.

Mapping the methylation pattern by bisulfite genomic sequencing of the E-cadherin promoter CpG island in nasopharyngeal carcinoma.

Kao RH, Huang LC, Hsu YH. Kao RH, et al. Anticancer Res. 2002 Nov-Dec;22(6C):4109-13. Anticancer Res. 2002. PMID: 12553040

Clusters of regulatory signals for RNA polymerase II transcription associated with Alu family repeats and CpG islands in human promoters.

Oei SL, Babich VS, Kazakov VI, Usmanova NM, Kropotov AV, Tomilin NV. Oei SL, et al. Genomics. 2004 May;83(5):873-82. doi: 10.1016/j.ygeno.2003.11.001. Genomics. 2004. PMID: 15081116

Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation.

Graff JR, Herman JG, Myöhänen S, Baylin SB, Vertino PM. Graff JR, et al. J Biol Chem. 1997 Aug 29;272(35):22322-9. doi: 10.1074/jbc.272.35.22322. J Biol Chem. 1997. PMID: 9268383 Free article.

Cell type-specific methylation of an intronic CpG island controls expression of the MCJ gene.

Strathdee G, Davies BR, Vass JK, Siddiqui N, Brown R. Strathdee G, et al. Carcinogenesis. 2004 May;25(5):693-701. doi: 10.1093/carcin/bgh066. Epub 2004 Jan 16. Carcinogenesis. 2004. PMID: 14729589

DNA methylation paradigm shift: 15-lipoxygenase-1 upregulation in prostatic intraepithelial neoplasia and prostate cancer by atypical promoter hypermethylation.

Kelavkar UP, Harya NS, Hutzley J, Bacich DJ, Monzon FA, Chandran U, Dhir R, O'Keefe DS. Kelavkar UP, et al. Prostaglandins Other Lipid Mediat. 2007 Jan;82(1-4):185-97. doi: 10.1016/j.prostaglandins.2006.05.015. Epub 2006 Jul 11. Prostaglandins Other Lipid Mediat. 2007. PMID: 17164146

Non-CpG cytosine methylation of p53 exon 5 in non-small cell lung carcinoma.

Kouidou S, Agidou T, Kyrkou A, Andreou A, Katopodi T, Georgiou E, Krikelis D, Dimitriadou A, Spanos P, Tsilikas C, Destouni H, Tzimagiorgis G. Kouidou S, et al. Lung Cancer. 2005 Dec;50(3):299-307. doi: 10.1016/j.lungcan.2005.06.012. Epub 2005 Aug 25. Lung Cancer. 2005. PMID: 16125822

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