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Items: 1 to 20 of 118

1.

Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.

Hagen TM, Liu J, Lykkesfeldt J, Wehr CM, Ingersoll RT, Vinarsky V, Bartholomew JC, Ames BN.

Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1870-5. Erratum in: Proc Natl Acad Sci U S A 2002 May 14;99(10):7184.

2.

Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid.

Liu J, Killilea DW, Ames BN.

Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1876-81. Erratum in: Proc Natl Acad Sci U S A 2002 May 14;99(10):7184.

3.

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid.

Liu J, Head E, Gharib AM, Yuan W, Ingersoll RT, Hagen TM, Cotman CW, Ames BN.

Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2356-61. Erratum in: Proc Natl Acad Sci U S A 2002 May 14;99(10):7184-5.

4.

Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity.

Hagen TM, Ingersoll RT, Wehr CM, Lykkesfeldt J, Vinarsky V, Bartholomew JC, Song MH, Ames BN.

Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9562-6.

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Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine.

Long J, Gao F, Tong L, Cotman CW, Ames BN, Liu J.

Neurochem Res. 2009 Apr;34(4):755-63. doi: 10.1007/s11064-008-9850-2. Epub 2008 Oct 10.

7.

(R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate.

Hagen TM, Ingersoll RT, Lykkesfeldt J, Liu J, Wehr CM, Vinarsky V, Bartholomew JC, Ames AB.

FASEB J. 1999 Feb;13(2):411-8.

PMID:
9973329
9.

Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats.

Aliev G, Liu J, Shenk JC, Fischbach K, Pacheco GJ, Chen SG, Obrenovich ME, Ward WF, Richardson AG, Smith MA, Gasimov E, Perry G, Ames BN.

J Cell Mol Med. 2009 Feb;13(2):320-33. doi: 10.1111/j.1582-4934.2008.00324.x. Epub 2008 Mar 28.

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12.

Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid.

Suh JH, Shigeno ET, Morrow JD, Cox B, Rocha AE, Frei B, Hagen TM.

FASEB J. 2001 Mar;15(3):700-6.

13.

Acetyl-L-carnitine and lipoic acid improve mitochondrial abnormalities and serum levels of liver enzymes in a mouse model of nonalcoholic fatty liver disease.

Kathirvel E, Morgan K, French SW, Morgan TR.

Nutr Res. 2013 Nov;33(11):932-41. doi: 10.1016/j.nutres.2013.08.001. Epub 2013 Sep 18.

PMID:
24176233
14.

Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles.

Christie LA, Opii WO, Head E, Araujo JA, de Rivera C, Milgram NW, Cotman CW.

Exp Gerontol. 2009 Dec;44(12):752-9. doi: 10.1016/j.exger.2009.08.012. Epub 2009 Sep 6.

15.

Chronic pretreatment with acetyl-L-carnitine and ±DL-α-lipoic acid protects against acute glutamate-induced neurotoxicity in rat brain by altering mitochondrial function.

Nagesh Babu G, Kumar A, Singh RL.

Neurotox Res. 2011 Feb;19(2):319-29. doi: 10.1007/s12640-010-9165-3. Epub 2010 Mar 9.

PMID:
20217290
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18.

Delaying the mitochondrial decay of aging with acetylcarnitine.

Ames BN, Liu J.

Ann N Y Acad Sci. 2004 Nov;1033:108-16. Review.

PMID:
15591008
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20.

Lipoic acid and acetyl-carnitine reverse iron-induced oxidative stress in human fibroblasts.

Lal A, Atamna W, Killilea DW, Suh JH, Ames BN.

Redox Rep. 2008;13(1):2-10. doi: 10.1179/135100008X259150.

PMID:
18284845

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