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Items: 1 to 20 of 226

2.

Functional analysis of LKB1/STK11 mutants and two aberrant isoforms found in Peutz-Jeghers Syndrome patients.

Boudeau J, Kieloch A, Alessi DR, Stella A, Guanti G, Resta N.

Hum Mutat. 2003 Feb;21(2):172.

PMID:
12552571
4.

LKB1, a protein kinase regulating cell proliferation and polarity.

Boudeau J, Sapkota G, Alessi DR.

FEBS Lett. 2003 Jul 3;546(1):159-65. Review.

5.

Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366.

Sapkota GP, Deak M, Kieloch A, Morrice N, Goodarzi AA, Smythe C, Shiloh Y, Lees-Miller SP, Alessi DR.

Biochem J. 2002 Dec 1;368(Pt 2):507-16.

6.

The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase.

Smith DP, Spicer J, Smith A, Swift S, Ashworth A.

Hum Mol Genet. 1999 Aug;8(8):1479-85.

7.

Regulation of the Wnt signalling component PAR1A by the Peutz-Jeghers syndrome kinase LKB1.

Spicer J, Rayter S, Young N, Elliott R, Ashworth A, Smith D.

Oncogene. 2003 Jul 24;22(30):4752-6.

PMID:
12879020
8.

Loss of cytoplasmic retention ability of mutant LKB1 found in Peutz-Jeghers syndrome patients.

Nezu J, Oku A, Shimane M.

Biochem Biophys Res Commun. 1999 Aug 11;261(3):750-5.

PMID:
10441497
9.

Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity.

Mehenni H, Gehrig C, Nezu J, Oku A, Shimane M, Rossier C, Guex N, Blouin JL, Scott HS, Antonarakis SE.

Am J Hum Genet. 1998 Dec;63(6):1641-50.

10.

Analysis of the LKB1-STRAD-MO25 complex.

Boudeau J, Scott JW, Resta N, Deak M, Kieloch A, Komander D, Hardie DG, Prescott AR, van Aalten DM, Alessi DR.

J Cell Sci. 2004 Dec 15;117(Pt 26):6365-75.

11.
12.

A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity.

Martin SG, St Johnston D.

Nature. 2003 Jan 23;421(6921):379-84.

PMID:
12540903
13.

Identification of a novel mRNA species of the LKB1/STK11 Peutz-Jeghers serine/threonine kinase.

Churchman M, Dowling B, Tomlinson IP.

DNA Seq. 1999;10(4-5):255-61.

PMID:
10727082
14.

Somatic mutation of the Peutz-Jeghers syndrome gene, LKB1/STK11, in malignant melanoma.

Guldberg P, thor Straten P, Ahrenkiel V, Seremet T, Kirkin AF, Zeuthen J.

Oncogene. 1999 Mar 4;18(9):1777-80.

15.

LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes.

Mehenni H, Lin-Marq N, Buchet-Poyau K, Reymond A, Collart MA, Picard D, Antonarakis SE.

Hum Mol Genet. 2005 Aug 1;14(15):2209-19.

16.
18.

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome.

Hemminki A, Markie D, Tomlinson I, Avizienyte E, Roth S, Loukola A, Bignell G, Warren W, Aminoff M, Höglund P, Järvinen H, Kristo P, Pelin K, Ridanpää M, Salovaara R, Toro T, Bodmer W, Olschwang S, Olsen AS, Stratton MR, de la Chapelle A, Aaltonen LA.

Nature. 1998 Jan 8;391(6663):184-7.

PMID:
9428765
19.

Arabidopsis PDK1: identification of sites important for activity and downstream phosphorylation of S6 kinase.

Otterhag L, Gustavsson N, Alsterfjord M, Pical C, Lehrach H, Gobom J, Sommarin M.

Biochimie. 2006 Jan;88(1):11-21.

PMID:
16125835
20.

LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1.

Smith DP, Rayter SI, Niederlander C, Spicer J, Jones CM, Ashworth A.

Hum Mol Genet. 2001 Dec 1;10(25):2869-77.

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