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Diabetic LDL inhibits cell-cycle progression via STAT5B and p21(waf).

Brizzi MF, Dentelli P, Pavan M, Rosso A, Gambino R, Grazia De Cesaris M, Garbarino G, Camussi G, Pagano G, Pegoraro L.

J Clin Invest. 2002 Jan;109(1):111-9.


STAT5 activation induced by diabetic LDL depends on LDL glycation and occurs via src kinase activity.

Brizzi MF, Dentelli P, Gambino R, Cabodi S, Cassader M, Castelli A, Defilippi P, Pegoraro L, Pagano G.

Diabetes. 2002 Nov;51(11):3311-7.


Angiopoietin 2 induces cell cycle arrest in endothelial cells: a possible mechanism involved in advanced plaque neovascularization.

Calvi C, Dentelli P, Pagano M, Rosso A, Pegoraro M, Giunti S, Garbarino G, Camussi G, Pegoraro L, Brizzi MF.

Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):511-8. Epub 2004 Jan 15.


Cell cycle exit during terminal erythroid differentiation is associated with accumulation of p27(Kip1) and inactivation of cdk2 kinase.

Hsieh FF, Barnett LA, Green WF, Freedman K, Matushansky I, Skoultchi AI, Kelley LL.

Blood. 2000 Oct 15;96(8):2746-54.


Downregulation of p21(waf/cip-1) mediates apoptosis of human hepatocellular carcinoma cells in response to interferon-gamma.

Detjen KM, Murphy D, Welzel M, Farwig K, Wiedenmann B, Rosewicz S.

Exp Cell Res. 2003 Jan 15;282(2):78-89.


v-Jun stimulates both cdk2 kinase activity and G1/S progression via transcriptional repression of p21 CIP1.

Maclaren A, Clark W, Black EJ, Gregory D, Fujii H, Gillespie DA.

Oncogene. 2003 Apr 24;22(16):2383-95.


Signal transducer and activator of transcription 5a (STAT5a) is required for eosinophil differentiation of human cord blood-derived CD34+ cells.

Buitenhuis M, Baltus B, Lammers JW, Coffer PJ, Koenderman L.

Blood. 2003 Jan 1;101(1):134-42. Epub 2002 Aug 15.


Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21(WAF1/Cip1) by STAT5.

Matsumura I, Ishikawa J, Nakajima K, Oritani K, Tomiyama Y, Miyagawa J, Kato T, Miyazaki H, Matsuzawa Y, Kanakura Y.

Mol Cell Biol. 1997 May;17(5):2933-43.


Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines.

Koga H, Sakisaka S, Harada M, Takagi T, Hanada S, Taniguchi E, Kawaguchi T, Sasatomi K, Kimura R, Hashimoto O, Ueno T, Yano H, Kojiro M, Sata M.

Hepatology. 2001 May;33(5):1087-97.


Involvement of p21 and p27 in the regulation of CDK activity and cell cycle progression in the regenerating liver.

Albrecht JH, Poon RY, Ahonen CL, Rieland BM, Deng C, Crary GS.

Oncogene. 1998 Apr 23;16(16):2141-50.


E1A can provoke G1 exit that is refractory to p21 and independent of activating cdk2.

Akli S, Zhan S, Abdellatif M, Schneider MD.

Circ Res. 1999 Aug 20;85(4):319-28.


Cyclin A downregulation and p21(cip1) upregulation correlate with GATA-6-induced growth arrest in glomerular mesangial cells.

Nagata D, Suzuki E, Nishimatsu H, Yoshizumi M, Mano T, Walsh K, Sata M, Kakoki M, Goto A, Omata M, Hirata Y.

Circ Res. 2000 Oct 13;87(8):699-704.


Modulation of cdk2, cyclin D1, p16INK4a, p21WAF and p27Kip1 expression in endothelial cells by TNF/IFN gamma.

Dormond O, Lejeune FJ, Ruegg C.

Anticancer Res. 2002 Nov-Dec;22(6A):3159-63.


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