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NXF1/p15 heterodimers are essential for mRNA nuclear export in Drosophila.

Herold A, Klymenko T, Izaurralde E.

RNA. 2001 Dec;7(12):1768-80.


TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.

Herold A, Suyama M, Rodrigues JP, Braun IC, Kutay U, Carmo-Fonseca M, Bork P, Izaurralde E.

Mol Cell Biol. 2000 Dec;20(23):8996-9008.


Mex67p mediates nuclear export of a variety of RNA polymerase II transcripts.

Hurt E, Strässer K, Segref A, Bailer S, Schlaich N, Presutti C, Tollervey D, Jansen R.

J Biol Chem. 2000 Mar 24;275(12):8361-8.


The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila.

Gatfield D, Le Hir H, Schmitt C, Braun IC, Köcher T, Wilm M, Izaurralde E.

Curr Biol. 2001 Oct 30;11(21):1716-21.


NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation.

Jun L, Frints S, Duhamel H, Herold A, Abad-Rodrigues J, Dotti C, Izaurralde E, Marynen P, Froyen G.

Curr Biol. 2001 Sep 18;11(18):1381-91.


Definition of global and transcript-specific mRNA export pathways in metazoans.

Farny NG, Hurt JA, Silver PA.

Genes Dev. 2008 Jan 1;22(1):66-78. Epub 2007 Dec 17.


Identification and characterization of the mouse nuclear export factor (Nxf) family members.

Tan W, Zolotukhin AS, Tretyakova I, Bear J, Lindtner S, Smulevitch SV, Felber BK.

Nucleic Acids Res. 2005 Jul 13;33(12):3855-65. Print 2005.


Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA.

Katahira J, Inoue H, Hurt E, Yoneda Y.

EMBO J. 2009 Mar 4;28(5):556-67. doi: 10.1038/emboj.2009.5. Epub 2009 Jan 22.


Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes.

Wiegand HL, Coburn GA, Zeng Y, Kang Y, Bogerd HP, Cullen BR.

Mol Cell Biol. 2002 Jan;22(1):245-56.


Genome-wide analysis of nuclear mRNA export pathways in Drosophila.

Herold A, Teixeira L, Izaurralde E.

EMBO J. 2003 May 15;22(10):2472-83.


Developmental regulation of the heat shock response by nuclear transport factor karyopherin-alpha3.

Fang X, Chen T, Tran K, Parker CS.

Development. 2001 Sep;128(17):3349-58.


Molecular cloning and functional characterization of mouse Nxf family gene products.

Sasaki M, Takeda E, Takano K, Yomogida K, Katahira J, Yoneda Y.

Genomics. 2005 May;85(5):641-53.


Conserved nuclear export sequences in Schizosaccharomyces pombe Mex67 and human TAP function in mRNA export by direct nuclear pore interactions.

Thakurta AG, Gopal G, Yoon JH, Saha T, Dhar R.

J Biol Chem. 2004 Apr 23;279(17):17434-42. Epub 2004 Feb 12.


Nuclear export of mRNA by TAP/NXF1 requires two nucleoporin-binding sites but not p15.

Braun IC, Herold A, Rode M, Izaurralde E.

Mol Cell Biol. 2002 Aug;22(15):5405-18.


Overexpression of TAP/p15 heterodimers bypasses nuclear retention and stimulates nuclear mRNA export.

Braun IC, Herold A, Rode M, Conti E, Izaurralde E.

J Biol Chem. 2001 Jun 8;276(23):20536-43. Epub 2001 Mar 19.


Mex67p of Schizosaccharomyces pombe interacts with Rae1p in mediating mRNA export.

Yoon JH, Love DC, Guhathakurta A, Hanover JA, Dhar R.

Mol Cell Biol. 2000 Dec;20(23):8767-82.


Nuclear export factor family protein participates in cytoplasmic mRNA trafficking.

Tretyakova I, Zolotukhin AS, Tan W, Bear J, Propst F, Ruthel G, Felber BK.

J Biol Chem. 2005 Sep 9;280(36):31981-90. Epub 2005 Jul 12.


RanBP2/Nup358 provides a major binding site for NXF1-p15 dimers at the nuclear pore complex and functions in nuclear mRNA export.

Forler D, Rabut G, Ciccarelli FD, Herold A, Köcher T, Niggeweg R, Bork P, Ellenberg J, Izaurralde E.

Mol Cell Biol. 2004 Feb;24(3):1155-67.


Epstein-Barr virus protein EB2 contains an N-terminal transferable nuclear export signal that promotes nucleocytoplasmic export by directly binding TAP/NXF1.

Juillard F, Hiriart E, Sergeant N, Vingtdeux-Didier V, Drobecq H, Sergeant A, Manet E, Gruffat H.

J Virol. 2009 Dec;83(24):12759-68. doi: 10.1128/JVI.01276-09. Epub 2009 Sep 30.

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