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11720458,9229328,17720736,15570076,19345093,14701765,15659495,18398608,18376234,11308248,12885808,15015625,12860947,17414627,10721170,15385127,15015621,19451710,17896145,16009952,19177020,15297195,11506488,12952567,16944151,9229321,19448415,10831355,19551382,11251955,10629652,15782313,9427794,15331924,12952566,9609106,20095915,12627817,19028627,11237378,20221830,10360656,12381905,15138365,7514557,9086006,16622264,20819832,20216061,15205194,22421001,14745869,16282707,16940809,11398887,16552438,16088232,20501625,23392240,15902461,16849749,23370661,8849291,14551509,9563887,18690095,20676676,22481063,11709562,22683364,12478014,19626652,17110626,10091755,6640551,11221829,20085903,17375304,15025796,19018087,16645323,9663421,12377643,16282708,21109376,19173998,20308874,15661564,10631458,10466439,9609105,15695501,10910061,16015036,15455965,12962525,9252703,12181242,12453335,11697839,23728706,17098421,9229320,12649097,11334725,21607556,17522863,21674854,9135491,12011135,12085178,8996150,11289404,9725047,12118027,15807931,11506487,10761764,11204660,17957505,11334726,21205083,22576338,11919232,11956258,11283925,19728906,10375099,19220378,9862058,19621525,19380443,17562448,22760079,15169794,14679122,21969501,14612895,20524401,10658524,9626798,1478292,25266443,10592766,17785765,7802447,11844821,11432632,15386371,10561212,22110208,24011937,9420015,27515842,10840069,11504519,21940361,12377644,26680816,3791482,9411644,6424937,11283924,16965689,9635919,8291915,10920138,15837702,11092115,16225697,10760756,18570745,17596644,11731512,12381900,19538878,15505621,8186171,15809521,21143694,18751414,14605864,16334762,15226770,16755175,11142487,9500010,22694897,12075739,8589018,23482781,1374724,11001391,24388340,16500914,11432353,10213210,9402173,8967732,21646604,17348458,16619589,22270106,9816087,10945486,16277094,27169752,15237580,11190302,20235750,18281264,27409828,9297861,9214274,12853356,16424679,22706176,25381393,12799627,30567527,19031956,14671682,17594712,16076695,20041325,26680927,10789559,19219602,17366798,12924449,18343948,1709259,30679026,26471890,15870935,12960738,12176786,16395593,26680866,8521237,16556086,12598342,11681244,9348573,17855190,8899313,17106441,21449681,11943899,22340403,24613905,16410698,10497678,15381935,10838491,22330318,32835356,18272910,25770151,10660737,7666089,15549590,17030548,21937127,18404784,15944779,8922194,17285136,11094307,9422563,20950119,2909291,26242208,10343193,10206296,16091760,21401804,9660540,12056709,19383814,20920998,10606252,9374077,19104814,10762745,9336359,19609538,12881395,23575907,15201502,12056700,17205869,11231942,19153122,10839290,31732876,9274455,10333701,14998850,16937105,3881176,10408744,12400974,19771243,2055582,16197621,27854101,11180520,26254409,19664225,11943891,15700033,7720986,12736112,14665617,9887241,11177747,11872339,23090038,17309856,25030089,11712813,15361099,17972024,20456688,12853353,9716035,17273745,12796023,12153595,12006767,9647611,10856097,11319291,11300322,7422177,23294608,27256667,9030944,11707982,11873382,15057142,30838483,17848948,19956516,19296535,20396545,12044507,1951175,24587632,28476844,19822513,20047135,22021820,24869761,19904267,22156449,28608993,8977579,21710244,11190304,20396550,8678538,29623500,31378656,14574916,2496369,15655604,12187328,2019865,12398998,8924021,11579639,2585018,12795847,8622016,8267390,27042229,1389518,26771865,16062074,10741695,11762813,26560483,14632600,19331183,8958038,12045457,33078235,25208577,34270794,12917039,21443091,8164048,16633299,20727737,9402315,10969613,11911312,25551355,11995701,26789262,299223,7577041,21806965,11521795,20941813,9817272,3193828,9081391,20695724,29875415,26125734,30892441,17470449,25638466,31492988,3201864,25253003,11943888,21174620,10952773,7180833,21695698,11989590,33281065,26515599,8980407,26680938,17520255,22843915,16340193,1844464,26392056,26805281,22790056,20514304,20597995,11567914,11300320,9757491,20566423,32296503,10563743,9365714,17848753,10868530,31519565,16739312,31169742,7826911,27906628,6224466,19181477,27306806,7273020,30640791,6791063,24195184,3945437,1030548,30043425,9845610,16773070,15319237,34330885,15539924,29637602,26210704,24969166,27749557,2123134,11707992,29374697,9215831,23501837,24270644,26309030,9095336,15688605,28120247,28536214,22740925,11896096,27628558,17127229,27186954,20443276,25547406,29441897,15152939,26328607,19746224,27733154,31660826,10778765,14970324,11044640,23990499,22022292,10388084,11033456,11246350,9847566,23801302,27105527,16493620,23788967,2645464,15655543,8217239,26844701,11995700,33881678,24997451,27209703,10650901,8669869,12056708,27942212,8608838,9393564,33511942,23078151,30074279,26413982,23613669,10936465,10738119,2670212,8958035,8016902,9399677,15289725,32801699,20551893,32801697,11886010,20354524,12176785,15477304,4177873,4882472,24011711,7284972,15591725,7917366,31519979,29535127,37012696,2345074,28214800,10442358,25372392,21483305,16502354,30711991,30382064,2205259,25544580,12771914,21955833,32536012,27230031,10820365,22594556,20155625,976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Results by year

Year	Number of Results
1964	1
1968	2
1969	1
1976	3
1979	1
1980	1
1981	4
1982	1
1983	3
1984	1
1985	2
1986	2
1988	4
1989	7
1990	6
1991	5
1992	3
1993	3
1994	9
1995	10
1996	21
1997	29
1998	22
1999	21
2000	31
2001	42
2002	40
2003	28
2004	38
2005	34
2006	31
2007	26
2008	22
2009	31
2010	32
2011	32
2012	19
2013	23
2014	20
2015	22
2016	31
2017	14
2018	16
2019	24
2020	17
2021	15
2022	9
2023	3
2024	0

711 results

Page of 72

Results by year

Page 1

Oxaliplatin and protracted venous infusion of 5-fluorouracil in patients with advanced or relapsed 5-fluorouracil pretreated colorectal cancer.

Chau I, Webb A, Cunningham D, Hill M, Waters JS, Norman A, Massey A. Chau I, et al. Br J Cancer. 2001 Nov 2;85(9):1258-64. doi: 10.1054/bjoc.2001.2036. Br J Cancer. 2001. PMID: 11720458 Free PMC article. Clinical Trial.

First-line protracted venous infusion fluorouracil with CisDDP or carboplatin in advanced colorectal cancer.

Garcia-Giralt E, Beuzeboc P, Deffontaines D, Diéras V, Dorval T, Jouve M, Palangie T, Scholl S, Pouillart P. Garcia-Giralt E, et al. J Infus Chemother. 1996 Summer;6(3):149-51. J Infus Chemother. 1996. PMID: 9229328 Clinical Trial.

Efficacy and safety of an irinotecan plus bolus 5-fluorouracil and L-leucovorin regimen for metastatic colorectal cancer in Japanese patients: experience in a single institution in Japan.

Yoshino T, Boku N, Onozawa Y, Hironaka S, Fukutomi A, Yamaguchi Y, Hasuike N, Yamazaki K, Machida N, Ono H. Yoshino T, et al. Jpn J Clin Oncol. 2007 Sep;37(9):686-91. doi: 10.1093/jjco/hym091. Epub 2007 Aug 24. Jpn J Clin Oncol. 2007. PMID: 17720736

Randomized multicenter phase II trial of bolus plus infusional fluorouracil/leucovorin compared with fluorouracil/leucovorin plus oxaliplatin as third-line treatment of patients with advanced colorectal cancer.

Kemeny N, Garay CA, Gurtler J, Hochster H, Kennedy P, Benson A, Brandt DS, Polikoff J, Wertheim M, Shumaker G, Hallman D, Burger B, Gupta S. Kemeny N, et al. J Clin Oncol. 2004 Dec 1;22(23):4753-61. doi: 10.1200/JCO.2004.03.119. J Clin Oncol. 2004. PMID: 15570076 Clinical Trial.

A meta-analysis of chemotherapy regimen fluorouracil/leucovorin/oxaliplatin compared with fluorouracil/leucovorin in treating advanced colorectal cancer.

Chen ML, Fang CH, Liang LS, Dai LH, Wang XK. Chen ML, et al. Surg Oncol. 2010 Mar;19(1):38-45. doi: 10.1016/j.suronc.2009.02.015. Epub 2009 Apr 2. Surg Oncol. 2010. PMID: 19345093

Multicenter phase II study of Nordic fluorouracil and folinic acid bolus schedule combined with oxaliplatin as first-line treatment of metastatic colorectal cancer.

Sørbye H, Glimelius B, Berglund A, Fokstuen T, Tveit KM, Braendengen M, Øgreid D, Dahl O. Sørbye H, et al. J Clin Oncol. 2004 Jan 1;22(1):31-8. doi: 10.1200/JCO.2004.05.188. J Clin Oncol. 2004. PMID: 14701765 Clinical Trial.

Intensive systemic chemotherapy combined with surgery for metastatic colorectal cancer: results of a phase II study.

Taïeb J, Artru P, Paye F, Louvet C, Perez N, André T, Gayet B, Hebbar M, Goebel FM, Tournigand C, Parc R, de Gramont A. Taïeb J, et al. J Clin Oncol. 2005 Jan 20;23(3):502-9. doi: 10.1200/JCO.2005.05.082. J Clin Oncol. 2005. PMID: 15659495 Clinical Trial.

Treatment outcomes of oxaliplatin, 5-FU, and leucovorin as salvage therapy for patients with advanced or metastatic gastric cancer: a retrospective analysis.

Seo HY, Kim DS, Choi YS, Sung HJ, Park KH, Choi IK, Kim SJ, Oh SC, Seo JH, Choi CW, Kim BS, Shin SW, Kim YH, Kim JS. Seo HY, et al. Cancer Chemother Pharmacol. 2009 Feb;63(3):433-9. doi: 10.1007/s00280-008-0753-3. Epub 2008 Apr 9. Cancer Chemother Pharmacol. 2009. PMID: 18398608

A retrospective study of bifractionated CPT-11 with LF5FU infusion (FOLFIRI-3) in colorectal cancer patients pretreated with oxaliplatin and CPT-11 containing chemotherapies.

Viel E, Demarchi MF, Chaigneau L, Nguyen T, Legat C, Stein U, Thiery-Vuillemin A, Limat S, Pivot X, Borg C. Viel E, et al. Am J Clin Oncol. 2008 Feb;31(1):89-94. doi: 10.1097/COC.0b013e318134ee9c. Am J Clin Oncol. 2008. PMID: 18376234

5-fluorouracil modulated by leucovorin, methotrexate and mitomycin: highly effective, low-cost chemotherapy for advanced colorectal cancer.

Sobrero A, Guglielmi A, Cirillo M, Recaldin E, Frassineti GL, Aschele C, Ravaioli A, Testore P, Caroti C, Gallo L, Pessi MA, Cortesi E, Turci D, Grossi F, Labianca R. Sobrero A, et al. Br J Cancer. 2001 Apr 20;84(8):1023-8. doi: 10.1054/bjoc.2001.1732. Br J Cancer. 2001. PMID: 11308248 Free PMC article. Clinical Trial.

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