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Items: 1 to 20 of 113


The pro-apoptotic Bcl-2 family member tBid localizes to mitochondrial contact sites.

Lutter M, Perkins GA, Wang X.

BMC Cell Biol. 2001;2:22. Epub 2001 Nov 8.


Cardiolipin provides specificity for targeting of tBid to mitochondria.

Lutter M, Fang M, Luo X, Nishijima M, Xie X, Wang X.

Nat Cell Biol. 2000 Oct;2(10):754-61.


Mechanistic issues of the interaction of the hairpin-forming domain of tBid with mitochondrial cardiolipin.

Gonzalvez F, Pariselli F, Jalmar O, Dupaigne P, Sureau F, Dellinger M, Hendrickson EA, Bernard S, Petit PX.

PLoS One. 2010 Feb 22;5(2):e9342. doi: 10.1371/journal.pone.0009342.


Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein.

Roucou X, Montessuit S, Antonsson B, Martinou JC.

Biochem J. 2002 Dec 15;368(Pt 3):915-21.


Bid-cardiolipin interaction at mitochondrial contact site contributes to mitochondrial cristae reorganization and cytochrome C release.

Kim TH, Zhao Y, Ding WX, Shin JN, He X, Seo YW, Chen J, Rabinowich H, Amoscato AA, Yin XM.

Mol Biol Cell. 2004 Jul;15(7):3061-72. Epub 2004 Apr 23.


Mitochondrial carrier homolog 2 is a target of tBID in cells signaled to die by tumor necrosis factor alpha.

Grinberg M, Schwarz M, Zaltsman Y, Eini T, Niv H, Pietrokovski S, Gross A.

Mol Cell Biol. 2005 Jun;25(11):4579-90.


Bid-induced cytochrome c release is mediated by a pathway independent of mitochondrial permeability transition pore and Bax.

Kim TH, Zhao Y, Barber MJ, Kuharsky DK, Yin XM.

J Biol Chem. 2000 Dec 15;275(50):39474-81.


tBid interaction with cardiolipin primarily orchestrates mitochondrial dysfunctions and subsequently activates Bax and Bak.

Gonzalvez F, Pariselli F, Dupaigne P, Budihardjo I, Lutter M, Antonsson B, Diolez P, Manon S, Martinou JC, Goubern M, Wang X, Bernard S, Petit PX.

Cell Death Differ. 2005 Jun;12(6):614-26.


Rapid kinetics of tBid-induced cytochrome c and Smac/DIABLO release and mitochondrial depolarization.

Madesh M, Antonsson B, Srinivasula SM, Alnemri ES, Hajnóczky G.

J Biol Chem. 2002 Feb 15;277(7):5651-9. Epub 2001 Dec 6.


The interaction between tBid and cardiolipin or monolysocardiolipin.

Liu J, Durrant D, Yang HS, He Y, Whitby FG, Myszka DG, Lee RM.

Biochem Biophys Res Commun. 2005 May 13;330(3):865-70.


The cardiolipin-binding domain of Bid affects mitochondrial respiration and enhances cytochrome c release.

Liu J, Weiss A, Durrant D, Chi NW, Lee RM.

Apoptosis. 2004 Sep;9(5):533-41.


tBid elicits a conformational alteration in membrane-bound Bcl-2 such that it inhibits Bax pore formation.

Peng J, Tan C, Roberts GJ, Nikolaeva O, Zhang Z, Lapolla SM, Primorac S, Andrews DW, Lin J.

J Biol Chem. 2006 Nov 24;281(47):35802-11. Epub 2006 Sep 27.


A membrane-targeted BID BCL-2 homology 3 peptide is sufficient for high potency activation of BAX in vitro.

Oh KJ, Barbuto S, Pitter K, Morash J, Walensky LD, Korsmeyer SJ.

J Biol Chem. 2006 Dec 1;281(48):36999-7008. Epub 2006 Sep 20.


Role of cardiolipin on tBid and tBid/Bax synergistic effects on yeast mitochondria.

Gonzalvez F, Bessoule JJ, Rocchiccioli F, Manon S, Petit PX.

Cell Death Differ. 2005 Jun;12(6):659-67.


Interaction of the alpha-helical H6 peptide from the pro-apoptotic protein tBid with cardiolipin.

Petit PX, Dupaigne P, Pariselli F, Gonzalvez F, Etienne F, Rameau C, Bernard S.

FEBS J. 2009 Nov;276(21):6338-54. doi: 10.1111/j.1742-4658.2009.07345.x. Epub 2009 Oct 1.


Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis.

Clohessy JG, Zhuang J, de Boer J, Gil-Gómez G, Brady HJ.

J Biol Chem. 2006 Mar 3;281(9):5750-9. Epub 2005 Dec 27.

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