Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 117


Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression.

Clerici M, Paciotti V, Baldo V, Romano M, Lucchini G, Longhese MP.

EMBO J. 2001 Nov 15;20(22):6485-98.


A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1.

Clerici M, Baldo V, Mantiero D, Lottersberger F, Lucchini G, Longhese MP.

Mol Cell Biol. 2004 Dec;24(23):10126-44.


Two checkpoint complexes are independently recruited to sites of DNA damage in vivo.

Melo JA, Cohen J, Toczyski DP.

Genes Dev. 2001 Nov 1;15(21):2809-21.


The ATM-related Tel1 protein of Saccharomyces cerevisiae controls a checkpoint response following phleomycin treatment.

Nakada D, Shimomura T, Matsumoto K, Sugimoto K.

Nucleic Acids Res. 2003 Mar 15;31(6):1715-24.


Srs2 DNA helicase is involved in checkpoint response and its regulation requires a functional Mec1-dependent pathway and Cdk1 activity.

Liberi G, Chiolo I, Pellicioli A, Lopes M, Plevani P, Muzi-Falconi M, Foiani M.

EMBO J. 2000 Sep 15;19(18):5027-38.


Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways.

Sun Z, Fay DS, Marini F, Foiani M, Stern DF.

Genes Dev. 1996 Feb 15;10(4):395-406.


Ddc2 mediates Mec1 activation through a Ddc1- or Dpb11-independent mechanism.

Bandhu A, Kang J, Fukunaga K, Goto G, Sugimoto K.

PLoS Genet. 2014 Feb 20;10(2):e1004136. doi: 10.1371/journal.pgen.1004136. eCollection 2014 Feb.


Dpb11 activates the Mec1-Ddc2 complex.

Mordes DA, Nam EA, Cortez D.

Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18730-4. doi: 10.1073/pnas.0806621105. Epub 2008 Nov 21.


CDC5 inhibits the hyperphosphorylation of the checkpoint kinase Rad53, leading to checkpoint adaptation.

Vidanes GM, Sweeney FD, Galicia S, Cheung S, Doyle JP, Durocher D, Toczyski DP.

PLoS Biol. 2010 Jan 26;8(1):e1000286. doi: 10.1371/journal.pbio.1000286.


Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.

Smolka MB, Albuquerque CP, Chen SH, Zhou H.

Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10364-9. Epub 2007 Jun 11.


The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation.

Baroni E, Viscardi V, Cartagena-Lirola H, Lucchini G, Longhese MP.

Mol Cell Biol. 2004 May;24(10):4151-65.


The checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint.

Majka J, Niedziela-Majka A, Burgers PM.

Mol Cell. 2006 Dec 28;24(6):891-901.


Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways.

Sanchez Y, Desany BA, Jones WJ, Liu Q, Wang B, Elledge SJ.

Science. 1996 Jan 19;271(5247):357-60.


Supplemental Content

Support Center