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Items: 1 to 20 of 484

1.

Upregulation of phosphodiesterase 1A1 expression is associated with the development of nitrate tolerance.

Kim D, Rybalkin SD, Pi X, Wang Y, Zhang C, Munzel T, Beavo JA, Berk BC, Yan C.

Circulation. 2001 Nov 6;104(19):2338-43.

2.

Contribution of phosphodiesterase isoenzymes and cyclic nucleotide efflux to the regulation of cyclic GMP levels in aortic smooth muscle cells.

Mercapide J, Santiago E, Alberdi E, Martinez-Irujo JJ.

Biochem Pharmacol. 1999 Nov 15;58(10):1675-83.

PMID:
10535760
3.

The role of phosphodiesterase isoforms 2, 5, and 9 in the regulation of NO-dependent and NO-independent cGMP production in the rat cervical spinal cord.

de Vente J, Markerink-van Ittersum M, Vles JS.

J Chem Neuroanat. 2006 Jun;31(4):275-303. Epub 2006 Apr 18.

PMID:
16621445
4.

Effects of in vivo nitroglycerin treatment on activity and expression of the guanylyl cyclase and cGMP-dependent protein kinase and their downstream target vasodilator-stimulated phosphoprotein in aorta.

Mülsch A, Oelze M, Klöss S, Mollnau H, Töpfer A, Smolenski A, Walter U, Stasch JP, Warnholtz A, Hink U, Meinertz T, Münzel T.

Circulation. 2001 May 1;103(17):2188-94.

5.

Inhibition of phosphodiesterase 5 selectively reverses nitrate tolerance in the venous circulation.

MacPherson JD, Gillespie TD, Dunkerley HA, Maurice DH, Bennett BM.

J Pharmacol Exp Ther. 2006 Apr;317(1):188-95. Epub 2005 Dec 5.

6.

Angiotensin II increases phosphodiesterase 5A expression in vascular smooth muscle cells: a mechanism by which angiotensin II antagonizes cGMP signaling.

Kim D, Aizawa T, Wei H, Pi X, Rybalkin SD, Berk BC, Yan C.

J Mol Cell Cardiol. 2005 Jan;38(1):175-84. Epub 2004 Dec 8.

7.
8.
9.

Changes in phosphodiesterase activity in the developing rat submandibular gland.

Tanaka S, Shimooka S, Shimomura H.

Arch Oral Biol. 2002 Aug;47(8):567-76.

PMID:
12221013
10.

Prevention of nitroglycerin tolerance in vitro by T0156, a selective phosphodiesterase type 5 inhibitor.

Liu CQ, Leung FP, Lee VW, Lau CW, Yao X, Lu L, Huang Y.

Eur J Pharmacol. 2008 Aug 20;590(1-3):250-4. doi: 10.1016/j.ejphar.2008.05.009. Epub 2008 May 20.

PMID:
18554583
11.

Cyclic GMP potentiation by WIN 58237, a novel cyclic nucleotide phosphodiesterase inhibitor.

Silver PJ, Dundore RL, Bode DC, de Garavilla L, Buchholz RA, van Aller G, Hamel LT, Bacon E, Singh B, Lesher GY, et al.

J Pharmacol Exp Ther. 1994 Dec;271(3):1143-9.

PMID:
7996419
12.

Angiotensin AT2 receptor mediated inhibition of particulate guanylate cyclase: a link with protein tyrosine phosphatase stimulation?

Brechler V, Levens NR, De Gasparo M, Bottari SP.

Receptors Channels. 1994;2(2):79-87.

PMID:
7525002
13.

Desensitization of NO/cGMP signaling in smooth muscle: blood vessels versus airways.

Mullershausen F, Lange A, Mergia E, Friebe A, Koesling D.

Mol Pharmacol. 2006 Jun;69(6):1969-74. Epub 2006 Mar 1.

14.
15.

Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells.

Zhu B, Strada S, Stevens T.

Am J Physiol Lung Cell Mol Physiol. 2005 Aug;289(2):L196-206. Epub 2005 Mar 25.

PMID:
15792963
16.

Reversal of nitroglycerin tolerance in vitro by the cGMP-phosphodiesterase inhibitor zaprinast.

Pagani ED, VanAller GS, O'Connor B, Silver PJ.

Eur J Pharmacol. 1993 Oct 19;243(2):141-7.

PMID:
8276063
17.
18.

The phosphodiesterase inhibitory selectivity and the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil.

Saenz de Tejada I, Angulo J, Cuevas P, Fernández A, Moncada I, Allona A, Lledó E, Körschen HG, Niewöhner U, Haning H, Pages E, Bischoff E.

Int J Impot Res. 2001 Oct;13(5):282-90.

PMID:
11890515
19.

Cyclic GMP phosphodiesterases and regulation of smooth muscle function.

Rybalkin SD, Yan C, Bornfeldt KE, Beavo JA.

Circ Res. 2003 Aug 22;93(4):280-91. Review.

20.

Role of phosphodiesterase 3 in NO/cGMP-mediated antiinflammatory effects in vascular smooth muscle cells.

Aizawa T, Wei H, Miano JM, Abe J, Berk BC, Yan C.

Circ Res. 2003 Sep 5;93(5):406-13. Epub 2003 Aug 14.

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