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Items: 1 to 20 of 53

1.

Mammalian TOR: a homeostatic ATP sensor.

Dennis PB, Jaeschke A, Saitoh M, Fowler B, Kozma SC, Thomas G.

Science. 2001 Nov 2;294(5544):1102-5.

2.

Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability.

Beugnet A, Tee AR, Taylor PM, Proud CG.

Biochem J. 2003 Jun 1;372(Pt 2):555-66. Erratum in: Biochem J. 2003 Aug 1;373(Pt 3):999.

3.

Identification of a conserved motif required for mTOR signaling.

Schalm SS, Blenis J.

Curr Biol. 2002 Apr 16;12(8):632-9.

4.

Phosphatidic acid-mediated mitogenic activation of mTOR signaling.

Fang Y, Vilella-Bach M, Bachmann R, Flanigan A, Chen J.

Science. 2001 Nov 30;294(5548):1942-5.

6.

Regulation of ribosomal S6 kinase 2 by mammalian target of rapamycin.

Park IH, Bachmann R, Shirazi H, Chen J.

J Biol Chem. 2002 Aug 30;277(35):31423-9.

7.

mTOR-mediated regulation of translation factors by amino acids.

Proud CG.

Biochem Biophys Res Commun. 2004 Jan 9;313(2):429-36. Review.

PMID:
14684180
9.

Rheb activation of mTOR and S6K1 signaling.

Hanrahan J, Blenis J.

Methods Enzymol. 2006;407:542-55.

PMID:
16757352
10.
11.

Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways.

Liu L, Li F, Cardelli JA, Martin KA, Blenis J, Huang S.

Oncogene. 2006 Nov 9;25(53):7029-40.

PMID:
16715128
12.

A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling.

Findlay GM, Yan L, Procter J, Mieulet V, Lamb RF.

Biochem J. 2007 Apr 1;403(1):13-20.

13.

The molecular target of rapamycin (mTOR) as a therapeutic target against cancer.

Mita MM, Mita A, Rowinsky EK.

Cancer Biol Ther. 2003 Jul-Aug;2(4 Suppl 1):S169-77. Review.

PMID:
14508096
15.

The mammalian target of rapamycin-signaling pathway in regulating metabolism and growth.

Yang X, Yang C, Farberman A, Rideout TC, de Lange CF, France J, Fan MZ.

J Anim Sci. 2008 Apr;86(14 Suppl):E36-50. Review.

16.

Will mTOR inhibitors make it as cancer drugs?

Sawyers CL.

Cancer Cell. 2003 Nov;4(5):343-8. Review. No abstract available.

17.

Amino acids and insulin control autophagic proteolysis through different signaling pathways in relation to mTOR in isolated rat hepatocytes.

Kanazawa T, Taneike I, Akaishi R, Yoshizawa F, Furuya N, Fujimura S, Kadowaki M.

J Biol Chem. 2004 Feb 27;279(9):8452-9.

18.
19.

Arginine and Leucine regulate p70 S6 kinase and 4E-BP1 in intestinal epithelial cells.

Ban H, Shigemitsu K, Yamatsuji T, Haisa M, Nakajo T, Takaoka M, Nobuhisa T, Gunduz M, Tanaka N, Naomoto Y.

Int J Mol Med. 2004 Apr;13(4):537-43.

PMID:
15010853
20.

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.

Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM.

Cell. 2002 Jul 26;110(2):163-75.

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