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Items: 1 to 20 of 1013

2.

Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4.

Hart KC, Robertson SC, Kanemitsu MY, Meyer AN, Tynan JA, Donoghue DJ.

Oncogene. 2000 Jul 6;19(29):3309-20.

PMID:
10918587
3.

The t(6;8)(q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to fibroblast growth factor receptor 1.

Popovici C, Zhang B, Grégoire MJ, Jonveaux P, Lafage-Pochitaloff M, Birnbaum D, Pébusque MJ.

Blood. 1999 Feb 15;93(4):1381-9.

PMID:
9949182
4.

FOP-FGFR1 tyrosine kinase, the product of a t(6;8) translocation, induces a fatal myeloproliferative disease in mice.

Guasch G, Delaval B, Arnoulet C, Xie MJ, Xerri L, Sainty D, Birnbaum D, Pébusque MJ.

Blood. 2004 Jan 1;103(1):309-12.

PMID:
12969958
5.

Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cgamma at the centrosome.

Lelièvre H, Chevrier V, Tassin AM, Birnbaum D.

Mol Cancer. 2008 Apr 15;7:30. doi: 10.1186/1476-4598-7-30.

PMID:
18412956
6.

Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations.

Roumiantsev S, Krause DS, Neumann CA, Dimitri CA, Asiedu F, Cross NC, Van Etten RA.

Cancer Cell. 2004 Mar;5(3):287-98.

PMID:
15050920
7.

Fusion of the BCR and the fibroblast growth factor receptor-1 (FGFR1) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder: the first fusion gene involving BCR but not ABL.

Fioretos T, Panagopoulos I, Lassen C, Swedin A, Billström R, Isaksson M, Strömbeck B, Olofsson T, Mitelman F, Johansson B.

Genes Chromosomes Cancer. 2001 Dec;32(4):302-10.

PMID:
11746971
8.

The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins.

Demiroglu A, Steer EJ, Heath C, Taylor K, Bentley M, Allen SL, Koduru P, Brody JP, Hawson G, Rodwell R, Doody ML, Carnicero F, Reiter A, Goldman JM, Melo JV, Cross NC.

Blood. 2001 Dec 15;98(13):3778-83.

PMID:
11739186
9.

[FGFR1 and MOZ, two key genes involved in malignant hemopathies linked to rearrangements within the chromosomal region 8p11-12].

Pébusque MJ, Chaffanet M, Popovici C, Birnbaum D.

Bull Cancer. 2000 Dec;87(12):887-94. Review. French.

PMID:
11174118
10.

Oncogenic tyrosine kinase of malignant hemopathy targets the centrosome.

Delaval B, Létard S, Lelièvre H, Chevrier V, Daviet L, Dubreuil P, Birnbaum D.

Cancer Res. 2005 Aug 15;65(16):7231-40.

PMID:
16103074
11.

ZNF198-FGFR1 transforms Ba/F3 cells to growth factor independence and results in high level tyrosine phosphorylation of STATS 1 and 5.

Smedley D, Demiroglu A, Abdul-Rauf M, Heath C, Cooper C, Shipley J, Cross NC.

Neoplasia. 1999 Oct;1(4):349-55.

PMID:
10935490
12.

Constitutively active Galpha16 stimulates STAT3 via a c-Src/JAK- and ERK-dependent mechanism.

Lo RK, Cheung H, Wong YH.

J Biol Chem. 2003 Dec 26;278(52):52154-65.

PMID:
14551213
13.

Characterization of FIM-FGFR1, the fusion product of the myeloproliferative disorder-associated t(8;13) translocation.

Ollendorff V, Guasch G, Isnardon D, Galindo R, Birnbaum D, Pébusque MJ.

J Biol Chem. 1999 Sep 17;274(38):26922-30.

PMID:
10480903
14.

Critical role of STAT5 activation in transformation mediated by ZNF198-FGFR1.

Heath C, Cross NC.

J Biol Chem. 2004 Feb 20;279(8):6666-73.

PMID:
14660670
15.

IL-2 activation of a PI3K-dependent STAT3 serine phosphorylation pathway in primary human T cells.

Fung MM, Rohwer F, McGuire KL.

Cell Signal. 2003 Jun;15(6):625-36.

PMID:
12681450
16.

The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells.

Cross MJ, Lu L, Magnusson P, Nyqvist D, Holmqvist K, Welsh M, Claesson-Welsh L.

Mol Biol Cell. 2002 Aug;13(8):2881-93.

PMID:
12181353
17.

Induction of apoptosis in IL-3-dependent hematopoietic cell lines by guanine nucleotide depletion.

Gu JJ, Gathy K, Santiago L, Chen E, Huang M, Graves LM, Mitchell BS.

Blood. 2003 Jun 15;101(12):4958-65.

PMID:
12609835
19.

Endogenous retroviral sequence is fused to FGFR1 kinase in the 8p12 stem-cell myeloproliferative disorder with t(8;19)(p12;q13.3).

Guasch G, Popovici C, Mugneret F, Chaffanet M, Pontarotti P, Birnbaum D, Pébusque MJ.

Blood. 2003 Jan 1;101(1):286-8.

PMID:
12393597
20.

Constitutively active STAT5 variants induce growth and survival of hematopoietic cells through a PI 3-kinase/Akt dependent pathway.

Santos SC, Lacronique V, Bouchaert I, Monni R, Bernard O, Gisselbrecht S, Gouilleux F.

Oncogene. 2001 Apr 19;20(17):2080-90.

PMID:
11360192
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