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Items: 1 to 20 of 121

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The conserved RING-H2 finger of ROC1 is required for ubiquitin ligation.

Chen A, Wu K, Fuchs SY, Tan P, Gomez C, Pan ZQ.

J Biol Chem. 2000 May 19;275(20):15432-9.

6.

Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail.

Yamoah K, Oashi T, Sarikas A, Gazdoiu S, Osman R, Pan ZQ.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12230-5. doi: 10.1073/pnas.0806155105. Epub 2008 Aug 22.

7.

Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stability.

Morimoto M, Nishida T, Nagayama Y, Yasuda H.

Biochem Biophys Res Commun. 2003 Feb 7;301(2):392-8.

PMID:
12565873
8.

Ubiquitin-conjugating enzyme Cdc34 and ubiquitin ligase Skp1-cullin-F-box ligase (SCF) interact through multiple conformations.

Sandoval D, Hill S, Ziemba A, Lewis S, Kuhlman B, Kleiger G.

J Biol Chem. 2015 Jan 9;290(2):1106-18. doi: 10.1074/jbc.M114.615559. Epub 2014 Nov 25.

9.

The acidic tail domain of human Cdc34 is required for p27Kip1 ubiquitination and complementation of a cdc34 temperature sensitive yeast strain.

Block K, Appikonda S, Lin HR, Bloom J, Pagano M, Yew PR.

Cell Cycle. 2005 Oct;4(10):1421-7. Epub 2005 Oct 26.

PMID:
16123592
10.

NEDD8 recruits E2-ubiquitin to SCF E3 ligase.

Kawakami T, Chiba T, Suzuki T, Iwai K, Yamanaka K, Minato N, Suzuki H, Shimbara N, Hidaka Y, Osaka F, Omata M, Tanaka K.

EMBO J. 2001 Aug 1;20(15):4003-12.

11.

Proximity-induced activation of human Cdc34 through heterologous dimerization.

Gazdoiu S, Yamoah K, Wu K, Escalante CR, Tappin I, Bermudez V, Aggarwal AK, Hurwitz J, Pan ZQ.

Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15053-8. Epub 2005 Oct 6.

12.

Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substrates.

Kleiger G, Saha A, Lewis S, Kuhlman B, Deshaies RJ.

Cell. 2009 Nov 25;139(5):957-68. doi: 10.1016/j.cell.2009.10.030.

13.

Human Cdc34 employs distinct sites to coordinate attachment of ubiquitin to a substrate and assembly of polyubiquitin chains.

Gazdoiu S, Yamoah K, Wu K, Pan ZQ.

Mol Cell Biol. 2007 Oct;27(20):7041-52. Epub 2007 Aug 13.

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Selective recruitment of an E2~ubiquitin complex by an E3 ubiquitin ligase.

Spratt DE, Wu K, Kovacev J, Pan ZQ, Shaw GS.

J Biol Chem. 2012 May 18;287(21):17374-85. doi: 10.1074/jbc.M112.353748. Epub 2012 Mar 20.

17.

The acidic tail of the Cdc34 ubiquitin-conjugating enzyme functions in both binding to and catalysis with ubiquitin ligase SCFCdc4.

Kleiger G, Hao B, Mohl DA, Deshaies RJ.

J Biol Chem. 2009 Dec 25;284(52):36012-23. doi: 10.1074/jbc.M109.058529. Epub 2009 Oct 29.

18.

The mechanism of poly-NEDD8 chain formation in vitro.

Ohki Y, Funatsu N, Konishi N, Chiba T.

Biochem Biophys Res Commun. 2009 Apr 10;381(3):443-7. doi: 10.1016/j.bbrc.2009.02.090. Epub 2009 Feb 24.

PMID:
19245792
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Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases.

Goldenberg SJ, Cascio TC, Shumway SD, Garbutt KC, Liu J, Xiong Y, Zheng N.

Cell. 2004 Nov 12;119(4):517-28.

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