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Items: 1 to 20 of 414

1.

Catalytic inhibition of human DNA topoisomerase IIalpha by hypericin, a naphthodianthrone from St. John's wort (Hypericum perforatum).

Peebles KA, Baker RK, Kurz EU, Schneider BJ, Kroll DJ.

Biochem Pharmacol. 2001 Oct 15;62(8):1059-70.

PMID:
11597574
2.

Chinese hamster ovary cells resistant to the topoisomerase II catalytic inhibitor ICRF-159: a Tyr49Phe mutation confers high-level resistance to bisdioxopiperazines.

Sehested M, Wessel I, Jensen LH, Holm B, Oliveri RS, Kenwrick S, Creighton AM, Nitiss JL, Jensen PB.

Cancer Res. 1998 Apr 1;58(7):1460-8.

3.

Benzene metabolites antagonize etoposide-stabilized cleavable complexes of DNA topoisomerase IIalpha.

Baker RK, Kurz EU, Pyatt DW, Irons RD, Kroll DJ.

Blood. 2001 Aug 1;98(3):830-3.

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[St. John's wort (Hypericum perforatum L.). A plant with relevance for dermatology].

Schempp CM, Müller KA, Winghofer B, Schöpf E, Simon JC.

Hautarzt. 2002 May;53(5):316-21. Review. German.

PMID:
12063742
9.

St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties.

Barnes J, Anderson LA, Phillipson JD.

J Pharm Pharmacol. 2001 May;53(5):583-600. Review.

PMID:
11370698
10.

Effects of wild-type p53 expression on the quantity and activity of topoisomerase IIalpha and beta in various human cancer cell lines.

Hochhauser D, Valkov NI, Gump JL, Wei I, O'Hare C, Hartley J, Fan J, Bertino JR, Banerjee D, Sullivan DM.

J Cell Biochem. 1999 Nov 1;75(2):245-57.

PMID:
10502297
11.

Altered drug interaction and regulation of topoisomerase IIbeta: potential mechanisms governing sensitivity of HL-60 cells to amsacrine and etoposide.

Grabowski DR, Holmes KA, Aoyama M, Ye Y, Rybicki LA, Bukowski RM, Ganapathi MK, Hickson ID, Ganapathi R.

Mol Pharmacol. 1999 Dec;56(6):1340-5.

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A unique paclitaxel-mediated modulation of the catalytic activity of topoisomerase IIalpha.

Dhawan V, Swaffar DS.

Anticancer Drugs. 1999 Apr;10(4):397-404.

PMID:
10378675
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Molecular and biochemical characterization of an enzyme responsible for the formation of hypericin in St. John's wort (Hypericum perforatum L.).

Bais HP, Vepachedu R, Lawrence CB, Stermitz FR, Vivanco JM.

J Biol Chem. 2003 Aug 22;278(34):32413-22. Epub 2003 Jun 10.

17.

Carbamate analogues of amsacrine active against non-cycling cells: relative activity against topoisomerases IIalpha and beta.

Turnbull RM, Meczes EL, Perenna Rogers M, Lock RB, Sullivan DM, Finlay GJ, Baguley BC, Austin CA.

Cancer Chemother Pharmacol. 1999;44(4):275-82.

PMID:
10447574
19.

Catalytic inhibition of DNA topoisomerase IIalpha by sodium azide.

Ju R, Mao Y, Glick MJ, Muller MT, Snyder RD.

Toxicol Lett. 2001 Apr 30;121(2):119-26.

PMID:
11325562
20.

Acetyl-boswellic acids are novel catalytic inhibitors of human topoisomerases I and IIalpha.

Syrovets T, Büchele B, Gedig E, Slupsky JR, Simmet T.

Mol Pharmacol. 2000 Jul;58(1):71-81.

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