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Disruption of Trrap causes early embryonic lethality and defects in cell cycle progression.

Herceg Z, Hulla W, Gell D, Cuenin C, Lleonart M, Jackson S, Wang ZQ.

Nat Genet. 2001 Oct;29(2):206-11.


HAT cofactor Trrap regulates the mitotic checkpoint by modulation of Mad1 and Mad2 expression.

Li H, Cuenin C, Murr R, Wang ZQ, Herceg Z.

EMBO J. 2004 Dec 8;23(24):4824-34. Epub 2004 Nov 18.


Disruption of the pelota gene causes early embryonic lethality and defects in cell cycle progression.

Adham IM, Sallam MA, Steding G, Korabiowska M, Brinck U, Hoyer-Fender S, Oh C, Engel W.

Mol Cell Biol. 2003 Feb;23(4):1470-6.


Genome-wide analysis of gene expression regulated by the HAT cofactor Trrap in conditional knockout cells.

Herceg Z, Li H, Cuenin C, Shukla V, Radolf M, Steinlein P, Wang ZQ.

Nucleic Acids Res. 2003 Dec 1;31(23):7011-23.


Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

Zhu J, Petersen S, Tessarollo L, Nussenzweig A.

Curr Biol. 2001 Jan 23;11(2):105-9.


Histone acetyltransferase cofactor Trrap is essential for maintaining the hematopoietic stem/progenitor cell pool.

Loizou JI, Oser G, Shukla V, Sawan C, Murr R, Wang ZQ, Trumpp A, Herceg Z.

J Immunol. 2009 Nov 15;183(10):6422-31. doi: 10.4049/jimmunol.0901969. Epub 2009 Oct 30.


Orchestration of chromatin-based processes: mind the TRRAP.

Murr R, Vaissière T, Sawan C, Shukla V, Herceg Z.

Oncogene. 2007 Aug 13;26(37):5358-72. Review.


Recruitment of TRRAP required for oncogenic transformation by E1A.

Deleu L, Shellard S, Alevizopoulos K, Amati B, Land H.

Oncogene. 2001 Dec 13;20(57):8270-5.


Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination.

Budzowska M, Jaspers I, Essers J, de Waard H, van Drunen E, Hanada K, Beverloo B, Hendriks RW, de Klein A, Kanaar R, Hoeijmakers JH, Maas A.

EMBO J. 2004 Sep 1;23(17):3548-58. Epub 2004 Aug 5.


Targeted disruption of the mouse ELYS gene results in embryonic death at peri-implantation development.

Okita K, Kiyonari H, Nobuhisa I, Kimura N, Aizawa S, Taga T.

Genes Cells. 2004 Nov;9(11):1083-91.


Down-regulation of TRRAP-dependent hTERT and TRRAP-independent CAD activation by Myc/Max contributes to the differentiation of HL60 cells after exposure to DMSO.

Jiang G, Bi K, Tang T, Wang J, Zhang Y, Zhang W, Ren H, Bai H, Wang Y.

Int Immunopharmacol. 2006 Jul;6(7):1204-13. Epub 2006 Apr 7.


The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

Xanthoudakis S, Smeyne RJ, Wallace JD, Curran T.

Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):8919-23.


Tissue-specific inactivation of HAT cofactor TRRAP reveals its essential role in B cells.

Leduc C, Chemin G, Puget N, Sawan C, Moutahir M, Herceg Z, Khamlichi AA.

Cell Cycle. 2014;13(10):1583-9. doi: 10.4161/cc.28560. Epub 2014 Mar 18.


A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture.

Johnson RS, van Lingen B, Papaioannou VE, Spiegelman BM.

Genes Dev. 1993 Jul;7(7B):1309-17.


Targeted disruption of the Rad51 gene leads to lethality in embryonic mice.

Tsuzuki T, Fujii Y, Sakumi K, Tominaga Y, Nakao K, Sekiguchi M, Matsushiro A, Yoshimura Y, MoritaT.

Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6236-40.


BRCT domain-containing protein PTIP is essential for progression through mitosis.

Cho EA, Prindle MJ, Dressler GR.

Mol Cell Biol. 2003 Mar;23(5):1666-73.


The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle.

Ichim G, Mola M, Finkbeiner MG, Cros MP, Herceg Z, Hernandez-Vargas H.

Oncogene. 2014 Jan 9;33(2):181-92. doi: 10.1038/onc.2012.570. Epub 2013 Jan 14.


Midgestation lethality in mice deficient for the RecA-related gene, Rad51d/Rad51l3.

Pittman DL, Schimenti JC.

Genesis. 2000 Mar;26(3):167-73.


Loss of histone acetyltransferase cofactor transformation/transcription domain-associated protein impairs liver regeneration after toxic injury.

Shukla V, Cuenin C, Dubey N, Herceg Z.

Hepatology. 2011 Mar;53(3):954-63. doi: 10.1002/hep.24120. Epub 2011 Feb 11.


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