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Items: 1 to 20 of 91

1.

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta.

Yuan M, Konstantopoulos N, Lee J, Hansen L, Li ZW, Karin M, Shoelson SE.

Science. 2001 Aug 31;293(5535):1673-7. Erratum in: Science 2002 Jan 11;295(5553):277.

2.

Inflammation and the IKK beta/I kappa B/NF-kappa B axis in obesity- and diet-induced insulin resistance.

Shoelson SE, Lee J, Yuan M.

Int J Obes Relat Metab Disord. 2003 Dec;27 Suppl 3:S49-52. Review.

PMID:
14704745
3.

[Effect of Berberine on the Insulin Resistance and TLR4/IKKbeta/NF-kappaB Signaling Pathways in Skeletal Muscle of Obese Rats with Insulin Resistance].

Zhang DS, Bai XH, Yao YJ, Mu DZ, Chen J.

Sichuan Da Xue Xue Bao Yi Xue Ban. 2015 Nov;46(6):827-31. Chinese.

PMID:
26867315
4.

A novel IKKbeta inhibitor stimulates adiponectin levels and ameliorates obesity-linked insulin resistance.

Kamon J, Yamauchi T, Muto S, Takekawa S, Ito Y, Hada Y, Ogawa W, Itai A, Kasuga M, Tobe K, Kadowaki T.

Biochem Biophys Res Commun. 2004 Oct 8;323(1):242-8.

PMID:
15351728
5.

Salicylate prevents hepatic insulin resistance caused by short-term elevation of free fatty acids in vivo.

Park E, Wong V, Guan X, Oprescu AI, Giacca A.

J Endocrinol. 2007 Nov;195(2):323-31.

6.

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB.

Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, Lee J, Shoelson SE.

Nat Med. 2005 Feb;11(2):183-90. Epub 2005 Jan 30.

8.
9.

Nutritionally induced insulin resistance and receptor defect leading to beta-cell failure in animal models.

Shafrir E, Ziv E, Mosthaf L.

Ann N Y Acad Sci. 1999 Nov 18;892:223-46. Review.

PMID:
10842665
11.

Central inhibition of IKKβ/NF-κB signaling attenuates high-fat diet-induced obesity and glucose intolerance.

Benzler J, Ganjam GK, Pretz D, Oelkrug R, Koch CE, Legler K, Stöhr S, Culmsee C, Williams LM, Tups A.

Diabetes. 2015 Jun;64(6):2015-27. doi: 10.2337/db14-0093. Epub 2015 Jan 27.

12.

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene.

Elchebly M, Payette P, Michaliszyn E, Cromlish W, Collins S, Loy AL, Normandin D, Cheng A, Himms-Hagen J, Chan CC, Ramachandran C, Gresser MJ, Tremblay ML, Kennedy BP.

Science. 1999 Mar 5;283(5407):1544-8.

13.

IKK-beta links inflammation to obesity-induced insulin resistance.

Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J, Karin M.

Nat Med. 2005 Feb;11(2):191-8. Epub 2005 Jan 30.

PMID:
15685170
14.

Chromium alleviates glucose intolerance, insulin resistance, and hepatic ER stress in obese mice.

Sreejayan N, Dong F, Kandadi MR, Yang X, Ren J.

Obesity (Silver Spring). 2008 Jun;16(6):1331-7. doi: 10.1038/oby.2008.217. Epub 2008 Apr 3.

15.

Conditional disruption of IkappaB kinase 2 fails to prevent obesity-induced insulin resistance.

Röhl M, Pasparakis M, Baudler S, Baumgartl J, Gautam D, Huth M, De Lorenzi R, Krone W, Rajewsky K, Brüning JC.

J Clin Invest. 2004 Feb;113(3):474-81.

16.

TANK-binding kinase 1 mediates phosphorylation of insulin receptor at serine residue 994: a potential link between inflammation and insulin resistance.

Muñoz MC, Giani JF, Mayer MA, Toblli JE, Turyn D, Dominici FP.

J Endocrinol. 2009 May;201(2):185-97. doi: 10.1677/JOE-08-0276. Epub 2009 Feb 27.

18.

Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet.

Posey KA, Clegg DJ, Printz RL, Byun J, Morton GJ, Vivekanandan-Giri A, Pennathur S, Baskin DG, Heinecke JW, Woods SC, Schwartz MW, Niswender KD.

Am J Physiol Endocrinol Metab. 2009 May;296(5):E1003-12. doi: 10.1152/ajpendo.90377.2008. Epub 2008 Dec 30.

19.
20.

Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.

Kang JH, Goto T, Han IS, Kawada T, Kim YM, Yu R.

Obesity (Silver Spring). 2010 Apr;18(4):780-7. doi: 10.1038/oby.2009.301. Epub 2009 Oct 1.

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