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Items: 1 to 20 of 475

1.

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

Lewis J, Dickson DW, Lin WL, Chisholm L, Corral A, Jones G, Yen SH, Sahara N, Skipper L, Yager D, Eckman C, Hardy J, Hutton M, McGowan E.

Science. 2001 Aug 24;293(5534):1487-91.

2.

Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice.

Ribé EM, Pérez M, Puig B, Gich I, Lim F, Cuadrado M, Sesma T, Catena S, Sánchez B, Nieto M, Gómez-Ramos P, Morán MA, Cabodevilla F, Samaranch L, Ortiz L, Pérez A, Ferrer I, Avila J, Gómez-Isla T.

Neurobiol Dis. 2005 Dec;20(3):814-22. Epub 2005 Aug 24.

PMID:
16125396
3.

Characterisation of cytoskeletal abnormalities in mice transgenic for wild-type human tau and familial Alzheimer's disease mutants of APP and presenilin-1.

Boutajangout A, Authelet M, Blanchard V, Touchet N, Tremp G, Pradier L, Brion JP.

Neurobiol Dis. 2004 Feb;15(1):47-60.

PMID:
14751770
4.

Biomedicine. Tauists and beta-aptists united--well almost!

Lee VM.

Science. 2001 Aug 24;293(5534):1446-7. No abstract available.

PMID:
11520974
5.

Enhanced accumulation of tau in doubly transgenic mice expressing mutant betaAPP and presenilin-1.

Samura E, Shoji M, Kawarabayashi T, Sasaki A, Matsubara E, Murakami T, Wuhua X, Tamura S, Ikeda M, Ishiguro K, Saido TC, Westaway D, St George Hyslop P, Harigaya Y, Abe K.

Brain Res. 2006 Jun 13;1094(1):192-9. Epub 2006 May 19.

PMID:
16713590
6.

[Alzheimer disease: cellular and molecular aspects].

Octave JN.

Bull Mem Acad R Med Belg. 2005;160(10-12):445-9; discussion 450-1. French.

PMID:
16768248
7.

Amyloid precursor protein cytoplasmic domain with phospho-Thr668 accumulates in Alzheimer's disease and its transgenic models: a role to mediate interaction of Abeta and tau.

Shin RW, Ogino K, Shimabuku A, Taki T, Nakashima H, Ishihara T, Kitamoto T.

Acta Neuropathol. 2007 Jun;113(6):627-36. Epub 2007 Mar 13.

PMID:
17431643
8.

A transgenic rat model of Alzheimer's disease with extracellular Abeta deposition.

Flood DG, Lin YG, Lang DM, Trusko SP, Hirsch JD, Savage MJ, Scott RW, Howland DS.

Neurobiol Aging. 2009 Jul;30(7):1078-90. Epub 2007 Nov 28.

PMID:
18053619
9.

Reduced Reelin expression accelerates amyloid-beta plaque formation and tau pathology in transgenic Alzheimer's disease mice.

Kocherhans S, Madhusudan A, Doehner J, Breu KS, Nitsch RM, Fritschy JM, Knuesel I.

J Neurosci. 2010 Jul 7;30(27):9228-40. doi: 10.1523/JNEUROSCI.0418-10.2010.

10.

Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.

Oddo S, Caccamo A, Kitazawa M, Tseng BP, LaFerla FM.

Neurobiol Aging. 2003 Dec;24(8):1063-70.

PMID:
14643377
11.

Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: insight from transgenic mouse and tissue-culture models.

Götz J, Schild A, Hoerndli F, Pennanen L.

Int J Dev Neurosci. 2004 Nov;22(7):453-65. Review.

PMID:
15465275
12.

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils.

Götz J, Chen F, van Dorpe J, Nitsch RM.

Science. 2001 Aug 24;293(5534):1491-5.

13.

Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.

van Groen T, Kiliaan AJ, Kadish I.

Neurobiol Dis. 2006 Sep;23(3):653-62. Epub 2006 Jul 10.

PMID:
16829076
14.

[The lesions of Alzheimer's disease: which therapeutic perspectives?].

Duyckaerts C, Perruchini C, Lebouvier T, Potier MC.

Bull Acad Natl Med. 2008 Feb;192(2):303-18; discussion 318-21. Review. French.

PMID:
18819685
15.

Phosphorylated tau in neuritic plaques of APP(sw)/Tau (vlw) transgenic mice and Alzheimer disease.

Pérez M, Morán MA, Ferrer I, Avila J, Gómez-Ramos P.

Acta Neuropathol. 2008 Oct;116(4):409-18. doi: 10.1007/s00401-008-0420-0. Epub 2008 Aug 5.

PMID:
18679696
16.

Phosphorylation of Tau at S422 is enhanced by Abeta in TauPS2APP triple transgenic mice.

Grueninger F, Bohrmann B, Czech C, Ballard TM, Frey JR, Weidensteiner C, von Kienlin M, Ozmen L.

Neurobiol Dis. 2010 Feb;37(2):294-306. doi: 10.1016/j.nbd.2009.09.004. Epub 2009 Sep 23.

PMID:
19781645
17.

Modeling Alzheimer's disease in transgenic mice: effect of age and of presenilin1 on amyloid biochemistry and pathology in APP/London mice.

Dewachter I, van Dorpe J, Spittaels K, Tesseur I, Van Den Haute C, Moechars D, Van Leuven F.

Exp Gerontol. 2000 Sep;35(6-7):831-41. Review.

PMID:
11053674
18.
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20.

Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease.

Schwab C, Hosokawa M, McGeer PL.

Exp Neurol. 2004 Jul;188(1):52-64.

PMID:
15191802
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