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11502884,10493515,16862172,9281609,14676829,16890209,14600251,16436093,15113942,17047224,15708369,18828601,11124824,12592390,11928805,17240450,9868178,16508969,16213476,12542977,20461739,19406223,15231486,12238566,10477620,10964666,8350491,22480519,11358979,20506079,10775421,11259102,25644976,9331105,15976760,12586742,10942531,10644043,10470285,14681684,21364905,10660762,16100442,10757128,11076697,16376342,14743383,15502883,17135765,10773882,11178969,12140289,15051936,11023547,21320497,12440226,17363366,11278274,23141425,9154181,11705450,20648542,22960171,24481129,19445683,18421862,21300025,20440723,11062165,20583309,11209110,20455202,10553091,21890837,9858893,10820281,16797629,24852948,12390026,19910690,10079014,15319365,17364504,19898545,17017850,18830563,11054378,19403032,15895106,12189048,21776820,8503918,18646540,15494532,15753951,17485788,12813046,10934439,18463684,18554517,9817203,24384371,19947947,18059161,11511526,12403772,12428978,33038311,19887561,30640129,18397796,12954803,12387357,20623641,23921304,21370452,32673149,24206194,10679280,8019435,23107691,17873830,15184672,25880992,18182252,15723090,12433185,27275932,9712707,10542212,22409219,12167626,17575143,22364573,22225636,11853893,10223207,11087528,26991948,21544063,15769601,22683870,11156183,10950844,8704303,23410590,15044435,11931850,16217757,10322768,19962294,19937554,10563991,25057854,12695345,22085033,24508265,17122395,11237202,15133034,15919367,18377686,15322359,12960117,10983895,19220840,22367622,16142404,20155623,10879132,11553681,19356313,9751250,10355038,16404707,19399671,23543313,8162603,12672147,22967044,22730927,12393936,21211509,22101032,14672711,26849416,21348516,7765013,22887905,15948241,17016632,24736877,11807163,20472400,11311209,28587181,18501505,20596647,15367703,9609384,15917555,23990052,22022384,26496857,20459029,24746834,12176021,30400620,21489792,10744042,24844145,23636906,26135316,15186836,15943584,10660664,15030231,26272391,11755158,11237204,10806303,20155620,9310136,12481431,18465779,25059833,9675322,10878235,10419449,31252129,22843790,20356444,17724029,24148349,22000973,8842748,12829720,10607735,20190037,25546248,11351279,12237322,32726662,11500915,25329972,14640574,21893494,9605416,10509743,21404918,32290071,12730857,12426080,18953110,29024813,15034065,9062630,12719785,11087533,15197771,23835657,20522783,36963358,30126206,12820420,17584048,11121366,11591714,11510478,11738479,19524070,27191001,28899730,34607205,28505110,34960802,7765153,20462508,1614998,9886579,20550744,26187476,25314656,24879560,32092951,18543393,30641474,11131648,24794014,28154178,7645982,16117624,16248575,24606444,18095272,12188632,20971568,15009657,16724910,18079119,20548792,12868553,10703004,22107329,31614951,16718374,10440930,20936703,7544258,34203004,15104213,17420597,12579647,12161102,18005251,31979082,22226360,16611078,28605495,34029903,33069855,14610487,15483420,9393670,14566988,35063850,23076424,24686838,23089520,20936888,11853888,27313063,36677584,15908794,26207957,25896296,32032735,12742577,11033196,10527519,11087552,19936622,18468251,21422740,10202393,12882539,20718469,15386386,27264099,26979632,33774797,28884125,11062155,18627310,28914528,33930649,17544279,22836624,33569875,15713670,18089804,26310506,21405989,9126320,19517063,19242551,29466429,32640594,10606745,17684143,27344138,12617920,11795518,10839202,11243706,12628509,10760511,23007066,12824047,10684130,29468843,11374875,15630232,12566308,11358376,34100197,35987428,11237203,25785827,20830699,23643524,11435526,21331509,17258915,31845690,14960276,25017180,14708018,1409493,25151997,21314234,11198218,12118006,25436420,32893422,19426837,33451050,14579522,21498061,28186133,26968537,7575552,28490136,30677765,14519824,15889414,10712742,19962296,35266367,21430251,16476731,30669068,10702779,11146219,24066304,20801632,15187230,29532213,11243881,32298262,20506578,11342184,11998565,35212538,31488855,33268644,11999122,10974202,31787396,10552595,16755003,27617982,23394110,8950350,26375250,11346351,11049215,23121921,33455167,25446466,12677145,15514297,19372735,36768179,23754277,26328543,11206275,10475615,11758774,25669488,29434699,10779623,9404069,17140430,36688583,11558573,12753472,12485906,10322769,28805446,11042267,24324066,21556548,22111071,21506932,12208473,17311952,20221615,23231348,25214095,9876974,16193318,11880178,25154916,21525624,27221834,30736313,16173528,32678222,31212946,10415792,32157685,21410257,10545959,12890480,23871988,35228387,30081748,29450132,27694921,15031715,35292341,18624451,10737211,12791687,23399841,10573853,10896383,30935522,36754155,30190600,15225717,22372602,24583869,17299992,31075724,11182527,17712586,20156174,1813062,33642735,21080642,35147416,10864017,1970233,10443459,10097515,10365250,10914035,12781855,15911271,21373880,19636434,21531558,27904095,12470903,28008665,19464566,15125939,12072354,18953479,33467101,35661183,11767119,35532615,24009774,33940571,15225718,22014009,31487001,35289676,25212306,19325839,31626054,21603032,34857232,27694956,19180671,36135185,216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The green tea polyphenol (-)-epigallocatechin-3-gallate blocks nuclear factor-kappa B activation by inhibiting I kappa B kinase activity in the intestinal epithelial cell line IEC-6.

Yang F, Oz HS, Barve S, de Villiers WJ, McClain CJ, Varilek GW. Yang F, et al. Mol Pharmacol. 2001 Sep;60(3):528-33. Mol Pharmacol. 2001. PMID: 11502884

Inhibition of activator protein 1 activity and cell growth by purified green tea and black tea polyphenols in H-ras-transformed cells: structure-activity relationship and mechanisms involved.

Chung JY, Huang C, Meng X, Dong Z, Yang CS. Chung JY, et al. Cancer Res. 1999 Sep 15;59(18):4610-7. Cancer Res. 1999. PMID: 10493515

Green tea polyphenol EGCG suppresses cigarette smoke condensate-induced NF-kappaB activation in normal human bronchial epithelial cells.

Syed DN, Afaq F, Kweon MH, Hadi N, Bhatia N, Spiegelman VS, Mukhtar H. Syed DN, et al. Oncogene. 2007 Feb 1;26(5):673-82. doi: 10.1038/sj.onc.1209829. Epub 2006 Jul 24. Oncogene. 2007. PMID: 16862172

(-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB.

Lin YL, Lin JK. Lin YL, et al. Mol Pharmacol. 1997 Sep;52(3):465-72. Mol Pharmacol. 1997. PMID: 9281609

Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappa B and induction of apoptosis.

Gupta S, Hastak K, Afaq F, Ahmad N, Mukhtar H. Gupta S, et al. Oncogene. 2004 Apr 1;23(14):2507-22. doi: 10.1038/sj.onc.1207353. Oncogene. 2004. PMID: 14676829

Suppression of MyD88- and TRIF-dependent signaling pathways of Toll-like receptor by (-)-epigallocatechin-3-gallate, a polyphenol component of green tea.

Youn HS, Lee JY, Saitoh SI, Miyake K, Kang KW, Choi YJ, Hwang DH. Youn HS, et al. Biochem Pharmacol. 2006 Sep 28;72(7):850-9. doi: 10.1016/j.bcp.2006.06.021. Epub 2006 Aug 4. Biochem Pharmacol. 2006. PMID: 16890209

Green tea polyphenol epigallocatechin-3-gallate (EGCG) differentially inhibits interleukin-1 beta-induced expression of matrix metalloproteinase-1 and -13 in human chondrocytes.

Ahmed S, Wang N, Lalonde M, Goldberg VM, Haqqi TM. Ahmed S, et al. J Pharmacol Exp Ther. 2004 Feb;308(2):767-73. doi: 10.1124/jpet.103.059220. Epub 2003 Nov 4. J Pharmacol Exp Ther. 2004. PMID: 14600251

Green tea polyphenol (-)-epigallocatechin-3-gallate inhibits ethanol-induced activation of pancreatic stellate cells.

Asaumi H, Watanabe S, Taguchi M, Tashiro M, Nagashio Y, Nomiyama Y, Nakamura H, Otsuki M. Asaumi H, et al. Eur J Clin Invest. 2006 Feb;36(2):113-22. doi: 10.1111/j.1365-2362.2006.01599.x. Eur J Clin Invest. 2006. PMID: 16436093

Epigallocatechin-3-gallate, a green tea-derived polyphenol, inhibits IL-1 beta-dependent proinflammatory signal transduction in cultured respiratory epithelial cells.

Wheeler DS, Catravas JD, Odoms K, Denenberg A, Malhotra V, Wong HR. Wheeler DS, et al. J Nutr. 2004 May;134(5):1039-44. doi: 10.1093/jn/134.5.1039. J Nutr. 2004. PMID: 15113942 Free article.

Regulation and function of IKK and IKK-related kinases.

Häcker H, Karin M. Häcker H, et al. Sci STKE. 2006 Oct 17;2006(357):re13. doi: 10.1126/stke.3572006re13. Sci STKE. 2006. PMID: 17047224 Review.

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