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Adenosine-mediated mast cell degranulation in adenosine deaminase-deficient mice.

Zhong H, Chunn JL, Volmer JB, Fozard JR, Blackburn MR.

J Pharmacol Exp Ther. 2001 Aug;298(2):433-40.


Activation of murine lung mast cells by the adenosine A3 receptor.

Zhong H, Shlykov SG, Molina JG, Sanborn BM, Jacobson MA, Tilley SL, Blackburn MR.

J Immunol. 2003 Jul 1;171(1):338-45.


Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice.

Chunn JL, Young HW, Banerjee SK, Colasurdo GN, Blackburn MR.

J Immunol. 2001 Oct 15;167(8):4676-85.


Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice.

Mohsenin A, Mi T, Xia Y, Kellems RE, Chen JF, Blackburn MR.

Am J Physiol Lung Cell Mol Physiol. 2007 Sep;293(3):L753-61. Epub 2007 Jun 29.


Adenosine-dependent pulmonary fibrosis in adenosine deaminase-deficient mice.

Chunn JL, Molina JG, Mi T, Xia Y, Kellems RE, Blackburn MR.

J Immunol. 2005 Aug 1;175(3):1937-46.


Identification of A3 receptor- and mast cell-dependent and -independent components of adenosine-mediated airway responsiveness in mice.

Tilley SL, Tsai M, Williams CM, Wang ZS, Erikson CJ, Galli SJ, Koller BH.

J Immunol. 2003 Jul 1;171(1):331-7.


Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction.

Blackburn MR, Volmer JB, Thrasher JL, Zhong H, Crosby JR, Lee JJ, Kellems RE.

J Exp Med. 2000 Jul 17;192(2):159-70.


Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation.

Jin X, Shepherd RK, Duling BR, Linden J.

J Clin Invest. 1997 Dec 1;100(11):2849-57.


A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice.

Young HW, Molina JG, Dimina D, Zhong H, Jacobson M, Chan LN, Chan TS, Lee JJ, Blackburn MR.

J Immunol. 2004 Jul 15;173(2):1380-9.


Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation.

Blackburn MR, Kellems RE.

Adv Immunol. 2005;86:1-41. Review.


Adenosine signaling in asthma and chronic obstructive pulmonary disease.

Mohsenin A, Blackburn MR.

Curr Opin Pulm Med. 2006 Jan;12(1):54-9. Review.


Suppression of adenosine A(3) receptor-mediated hypotension and mast cell degranulation in the rat by dexamethasone.

Hannon JP, Tigani B, Schuurman HJ, Fozard JR.

J Pharmacol Exp Ther. 2002 Aug;302(2):725-30.


Impaired germinal center maturation in adenosine deaminase deficiency.

Aldrich MB, Chen W, Blackburn MR, Martinez-Valdez H, Datta SK, Kellems RE.

J Immunol. 2003 Nov 15;171(10):5562-70.


The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice. Differential impact on pulmonary and immunologic abnormalities.

Blackburn MR, Aldrich M, Volmer JB, Chen W, Zhong H, Kelly S, Hershfield MS, Datta SK, Kellems RE.

J Biol Chem. 2000 Oct 13;275(41):32114-21.


Activation of adenosine A2 alpha receptors inhibits mast cell degranulation and mast cell-dependent vasoconstriction.

Fenster MS, Shepherd RK, Linden J, Duling BR.

Microcirculation. 2000 Apr;7(2):129-35.


Receptors and signaling mechanisms required for prostaglandin E2-mediated regulation of mast cell degranulation and IL-6 production.

Nguyen M, Solle M, Audoly LP, Tilley SL, Stock JL, McNeish JD, Coffman TM, Dombrowicz D, Koller BH.

J Immunol. 2002 Oct 15;169(8):4586-93.


Insights into thymic purine metabolism and adenosine deaminase deficiency revealed by transgenic mice overexpressing ecto-5'-nucleotidase (CD73).

Resta R, Hooker SW, Laurent AB, Jamshedur Rahman SM, Franklin M, Knudsen TB, Nadon NL, Thompson LF.

J Clin Invest. 1997 Feb 15;99(4):676-83.


Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations.

Chunn JL, Mohsenin A, Young HW, Lee CG, Elias JA, Kellems RE, Blackburn MR.

Am J Physiol Lung Cell Mol Physiol. 2006 Mar;290(3):L579-87. Epub 2005 Oct 28.


Adenosine and adenosine receptors in the pathomechanism and treatment of respiratory diseases.

Vass G, Horváth I.

Curr Med Chem. 2008;15(9):917-22. Review.

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