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Items: 1 to 20 of 224

1.

Amyotrophic lateral sclerosis: pathogenesis.

Brown RH Jr, Robberecht W.

Semin Neurol. 2001 Jun;21(2):131-9. Review.

PMID:
11442322
2.

Early pathogenesis in the adult-onset neurodegenerative disease amyotrophic lateral sclerosis.

van Zundert B, Izaurieta P, Fritz E, Alvarez FJ.

J Cell Biochem. 2012 Nov;113(11):3301-12. doi: 10.1002/jcb.24234.

3.

Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease.

Nagai M, Aoki M, Miyoshi I, Kato M, Pasinelli P, Kasai N, Brown RH Jr, Itoyama Y.

J Neurosci. 2001 Dec 1;21(23):9246-54.

4.

Molecular biology of amyotrophic lateral sclerosis: insights from genetics.

Pasinelli P, Brown RH.

Nat Rev Neurosci. 2006 Sep;7(9):710-23. Review.

PMID:
16924260
5.

Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.

Mackenzie IR, Bigio EH, Ince PG, Geser F, Neumann M, Cairns NJ, Kwong LK, Forman MS, Ravits J, Stewart H, Eisen A, McClusky L, Kretzschmar HA, Monoranu CM, Highley JR, Kirby J, Siddique T, Shaw PJ, Lee VM, Trojanowski JQ.

Ann Neurol. 2007 May;61(5):427-34.

PMID:
17469116
6.

Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex.

Zhang F, Ström AL, Fukada K, Lee S, Hayward LJ, Zhu H.

J Biol Chem. 2007 Jun 1;282(22):16691-9.

7.

Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA.

Wang J, Xu G, Slunt HH, Gonzales V, Coonfield M, Fromholt D, Copeland NG, Jenkins NA, Borchelt DR.

Neurobiol Dis. 2005 Dec;20(3):943-52.

PMID:
16046140
8.
9.

Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis.

Turner BJ, Atkin JD, Farg MA, Zang DW, Rembach A, Lopes EC, Patch JD, Hill AF, Cheema SS.

J Neurosci. 2005 Jan 5;25(1):108-17.

10.

[Familial amyotrophic lateral sclerosis and mutations in the Cu/Zn superoxide dismutase gene].

Nakano R.

Rinsho Shinkeigaku. 1995 Dec;35(12):1546-8. Review. Japanese.

PMID:
8752459
11.
12.

Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice.

Jaarsma D, Teuling E, Haasdijk ED, De Zeeuw CI, Hoogenraad CC.

J Neurosci. 2008 Feb 27;28(9):2075-88. doi: 10.1523/JNEUROSCI.5258-07.2008.

13.

From Charcot to SOD1: mechanisms of selective motor neuron death in ALS.

Cleveland DW.

Neuron. 1999 Nov;24(3):515-20. Review. No abstract available.

14.

Oxidative stress in ALS: key role in motor neuron injury and therapeutic target.

Barber SC, Shaw PJ.

Free Radic Biol Med. 2010 Mar 1;48(5):629-41. doi: 10.1016/j.freeradbiomed.2009.11.018. Review.

PMID:
19969067
15.

Lack of TDP-43 abnormalities in mutant SOD1 transgenic mice shows disparity with ALS.

Robertson J, Sanelli T, Xiao S, Yang W, Horne P, Hammond R, Pioro EP, Strong MJ.

Neurosci Lett. 2007 Jun 13;420(2):128-32.

PMID:
17543992
16.

Protein misdirection inside and outside motor neurons in Amyotrophic Lateral Sclerosis (ALS): a possible clue for therapeutic strategies.

Ido A, Fukuyama H, Urushitani M.

Int J Mol Sci. 2011;12(10):6980-7003. doi: 10.3390/ijms12106980. Review.

17.

Superoxide dismutase-1 mutation-related neurotoxicity in familial amyotrophic lateral sclerosis.

Shibata N, Hirano A, Yamamoto T, Kato Y, Kobayashi M.

Amyotroph Lateral Scler Other Motor Neuron Disord. 2000 Jun;1(3):143-61. Review.

PMID:
11464949
19.

Mitochondrial dysfunction and its role in motor neuron degeneration in ALS.

Manfredi G, Xu Z.

Mitochondrion. 2005 Apr;5(2):77-87. Review.

PMID:
16050975
20.
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