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Items: 1 to 20 of 102

1.

Partial HIF-1alpha deficiency impairs pulmonary arterial myocyte electrophysiological responses to hypoxia.

Shimoda LA, Manalo DJ, Sham JS, Semenza GL, Sylvester JT.

Am J Physiol Lung Cell Mol Physiol. 2001 Jul;281(1):L202-8.

2.

Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha.

Yu AY, Shimoda LA, Iyer NV, Huso DL, Sun X, McWilliams R, Beaty T, Sham JS, Wiener CM, Sylvester JT, Semenza GL.

J Clin Invest. 1999 Mar;103(5):691-6.

3.

Regulation of hypoxia-induced pulmonary hypertension by vascular smooth muscle hypoxia-inducible factor-1α.

Ball MK, Waypa GB, Mungai PT, Nielsen JM, Czech L, Dudley VJ, Beussink L, Dettman RW, Berkelhamer SK, Steinhorn RH, Shah SJ, Schumacker PT.

Am J Respir Crit Care Med. 2014 Feb 1;189(3):314-24. doi: 10.1164/rccm.201302-0302OC.

4.

Sirtuin 3 deficiency does not augment hypoxia-induced pulmonary hypertension.

Waypa GB, Osborne SW, Marks JD, Berkelhamer SK, Kondapalli J, Schumacker PT.

Am J Respir Cell Mol Biol. 2013 Dec;49(6):885-91. doi: 10.1165/rcmb.2013-0191OC.

5.

Hypoxia-inducible factor-1α in pulmonary artery smooth muscle cells lowers vascular tone by decreasing myosin light chain phosphorylation.

Kim YM, Barnes EA, Alvira CM, Ying L, Reddy S, Cornfield DN.

Circ Res. 2013 Apr 26;112(9):1230-3. doi: 10.1161/CIRCRESAHA.112.300646. Epub 2013 Mar 19.

6.

p53 Gene deficiency promotes hypoxia-induced pulmonary hypertension and vascular remodeling in mice.

Mizuno S, Bogaard HJ, Kraskauskas D, Alhussaini A, Gomez-Arroyo J, Voelkel NF, Ishizaki T.

Am J Physiol Lung Cell Mol Physiol. 2011 May;300(5):L753-61. doi: 10.1152/ajplung.00286.2010. Epub 2011 Feb 18.

7.

Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha.

Kline DD, Peng YJ, Manalo DJ, Semenza GL, Prabhakar NR.

Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):821-6. Epub 2002 Jan 15.

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10.

Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.

Archer SL, Wu XC, Thébaud B, Nsair A, Bonnet S, Tyrrell B, McMurtry MS, Hashimoto K, Harry G, Michelakis ED.

Circ Res. 2004 Aug 6;95(3):308-18. Epub 2004 Jun 24.

11.

HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes.

Shimoda LA, Fallon M, Pisarcik S, Wang J, Semenza GL.

Am J Physiol Lung Cell Mol Physiol. 2006 Nov;291(5):L941-9. Epub 2006 Jun 9.

12.

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha.

Iyer NV, Kotch LE, Agani F, Leung SW, Laughner E, Wenger RH, Gassmann M, Gearhart JD, Lawler AM, Yu AY, Semenza GL.

Genes Dev. 1998 Jan 15;12(2):149-62.

13.

[Effects of RNAi on hypoxia inducible factor-1alpha activity and proliferation of hypoxic pulmonary artery smooth muscle cells in rat].

Zhang W, Cao Y, Zhang Y, Ma QS, Ma L, Ge RL.

Sheng Li Xue Bao. 2006 Feb 25;58(1):71-6. Chinese.

14.

Deficiency of NOX1/nicotinamide adenine dinucleotide phosphate, reduced form oxidase leads to pulmonary vascular remodeling.

Iwata K, Ikami K, Matsuno K, Yamashita T, Shiba D, Ibi M, Matsumoto M, Katsuyama M, Cui W, Zhang J, Zhu K, Takei N, Kokai Y, Ohneda O, Yokoyama T, Yabe-Nishimura C.

Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):110-9. doi: 10.1161/ATVBAHA.113.302107. Epub 2013 Nov 14.

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16.

Chronic hypoxia alters effects of endothelin and angiotensin on K+ currents in pulmonary arterial myocytes.

Shimoda LA, Sylvester JT, Sham JS.

Am J Physiol. 1999 Sep;277(3 Pt 1):L431-9.

17.

Role of voltage-gated potassium channels in pathogenesis of chronic pulmonary heart disease.

Ke QM, Wu J, Tian L, Li W, Du YM.

J Huazhong Univ Sci Technolog Med Sci. 2013 Oct;33(5):644-9. doi: 10.1007/s11596-013-1174-z. Epub 2013 Oct 20.

PMID:
24142714
18.

Functional analysis of the role of hypoxia-inducible factor 1 in the pathogenesis of hypoxic pulmonary hypertension.

Shimoda LA, Semenza GL.

Methods Enzymol. 2004;381:121-9. No abstract available.

PMID:
15063669
20.

Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes.

Archer SL, Souil E, Dinh-Xuan AT, Schremmer B, Mercier JC, El Yaagoubi A, Nguyen-Huu L, Reeve HL, Hampl V.

J Clin Invest. 1998 Jun 1;101(11):2319-30.

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