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Geldanamycin, a potent and specific inhibitor of Hsp90, inhibits gene expression and replication of human cytomegalovirus.

Basha W, Kitagawa R, Uhara M, Imazu H, Uechi K, Tanaka J.

Antivir Chem Chemother. 2005;16(2):135-46.


Respiratory syncytial virus inhibits apoptosis and induces NF-kappa B activity through a phosphatidylinositol 3-kinase-dependent pathway.

Thomas KW, Monick MM, Staber JM, Yarovinsky T, Carter AB, Hunninghake GW.

J Biol Chem. 2002 Jan 4;277(1):492-501. Epub 2001 Oct 30.


Overexpression of interferon-gamma-inducible GTPase inhibits coxsackievirus B3-induced apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway and inhibition of viral replication.

Zhang HM, Yuan J, Cheung P, Luo H, Yanagawa B, Chau D, Stephan-Tozy N, Wong BW, Zhang J, Wilson JE, McManus BM, Yang D.

J Biol Chem. 2003 Aug 29;278(35):33011-9. Epub 2003 Jun 20.


Constitutive NF-kappaB DNA-binding activity in AML is frequently mediated by a Ras/PI3-K/PKB-dependent pathway.

Birkenkamp KU, Geugien M, Schepers H, Westra J, Lemmink HH, Vellenga E.

Leukemia. 2004 Jan;18(1):103-12.


Inhibition of phosphatidylinositol 3'-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells.

Uddin S, Hussain AR, Al-Hussein KA, Manogaran PS, Wickrema A, Gutierrez MI, Bhatia KG.

Clin Cancer Res. 2005 Apr 15;11(8):3102-8.


Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.

Pene F, Claessens YE, Muller O, Viguié F, Mayeux P, Dreyfus F, Lacombe C, Bouscary D.

Oncogene. 2002 Sep 26;21(43):6587-97.


Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma.

Hideshima T, Nakamura N, Chauhan D, Anderson KC.

Oncogene. 2001 Sep 20;20(42):5991-6000.


Extracellular zinc activates p70 S6 kinase through the phosphatidylinositol 3-kinase signaling pathway.

Kim S, Jung Y, Kim D, Koh H, Chung J.

J Biol Chem. 2000 Aug 25;275(34):25979-84.


Suppression of apoptosis by pseudorabies virus Us3 protein kinase through the activation of PI3-K/Akt and NF-κB pathways.

Chang CD, Lin PY, Liao MH, Chang CI, Hsu JL, Yu FL, Wu HY, Shih WL.

Res Vet Sci. 2013 Oct;95(2):764-74. doi: 10.1016/j.rvsc.2013.06.003. Epub 2013 Jul 5.


BCR signals target p27(Kip1) and cyclin D2 via the PI3-K signalling pathway to mediate cell cycle arrest and apoptosis of WEHI 231 B cells.

Banerji L, Glassford J, Lea NC, Thomas NS, Klaus GG, Lam EW.

Oncogene. 2001 Nov 1;20(50):7352-67.


The phosphatidylinositol 3-kinase/Akt signaling pathway modulates the endocrine differentiation of trophoblast cells.

Kamei T, Jones SR, Chapman BM, MCGonigle KL, Dai G, Soares MJ.

Mol Endocrinol. 2002 Jul;16(7):1469-81.


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