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Items: 1 to 20 of 185

1.

Differential cross talk of ROD compounds with the benzodiazepine binding site.

Sigel E, Baur R, Furtmueller R, Razet R, Dodd RH, Sieghart W.

Mol Pharmacol. 2001 Jun;59(6):1470-7.

3.

Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs.

Baur R, Tan KR, Lüscher BP, Gonthier A, Goeldner M, Sigel E.

J Neurochem. 2008 Sep;106(6):2353-63. doi: 10.1111/j.1471-4159.2008.05574.x. Epub 2008 Jul 15.

4.

A novel positive allosteric modulator of the GABA(A) receptor: the action of (+)-ROD188.

Thomet U, Baur R, Razet R, Dodd RH, Furtmüller R, Sieghart W, Sigel E.

Br J Pharmacol. 2000 Oct;131(4):843-50.

5.
6.

An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons.

Ahboucha S, Coyne L, Hirakawa R, Butterworth RF, Halliwell RF.

Neurochem Int. 2006 Jun;48(8):703-7. Epub 2006 Feb 17.

PMID:
16487630
7.

Molecular basis for modulation of recombinant alpha1beta2gamma2 GABAA receptors by protons.

Huang RQ, Chen Z, Dillon GH.

J Neurophysiol. 2004 Aug;92(2):883-94. Epub 2004 Mar 17.

8.

Inhibition of type A GABA receptors by L-type calcium channel blockers.

Das P, Bell-Horner CL, Huang RQ, Raut A, Gonzales EB, Chen ZL, Covey DF, Dillon GH.

Neuroscience. 2004;124(1):195-206.

PMID:
14960351
9.

Relative positioning of diazepam in the benzodiazepine-binding-pocket of GABA receptors.

Tan KR, Baur R, Charon S, Goeldner M, Sigel E.

J Neurochem. 2009 Dec;111(5):1264-73. doi: 10.1111/j.1471-4159.2009.06419.x. Epub 2009 Oct 5.

10.

On the benzodiazepine binding pocket in GABAA receptors.

Berezhnoy D, Nyfeler Y, Gonthier A, Schwob H, Goeldner M, Sigel E.

J Biol Chem. 2004 Jan 30;279(5):3160-8. Epub 2003 Nov 11.

12.

Novel plant substances acting as beta subunit isoform-selective positive allosteric modulators of GABAA receptors.

Baur R, Simmen U, Senn M, Séquin U, Sigel E.

Mol Pharmacol. 2005 Sep;68(3):787-92. Epub 2005 Jun 6.

15.

Isoliquiritigenin, a chalcone compound, is a positive allosteric modulator of GABAA receptors and shows hypnotic effects.

Cho S, Kim S, Jin Z, Yang H, Han D, Baek NI, Jo J, Cho CW, Park JH, Shimizu M, Jin YH.

Biochem Biophys Res Commun. 2011 Oct 7;413(4):637-42. doi: 10.1016/j.bbrc.2011.09.026. Epub 2011 Sep 14.

PMID:
21945440
19.

Conformational changes at benzodiazepine binding sites of GABA(A) receptors detected with a novel technique.

Berezhnoy D, Baur R, Gonthier A, Foucaud B, Goeldner M, Sigel E.

J Neurochem. 2005 Feb;92(4):859-66.

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