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Items: 1 to 20 of 95

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Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila.

Le Borgne R, Remaud S, Hamel S, Schweisguth F.

PLoS Biol. 2005 Apr;3(4):e96. Epub 2005 Mar 15.

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Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta.

Lai EC, Deblandre GA, Kintner C, Rubin GM.

Dev Cell. 2001 Dec;1(6):783-94.

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Structural and functional characterization of the NHR1 domain of the Drosophila neuralized E3 ligase in the notch signaling pathway.

He F, Saito K, Kobayashi N, Harada T, Watanabe S, Kigawa T, Güntert P, Ohara O, Tanaka A, Unzai S, Muto Y, Yokoyama S.

J Mol Biol. 2009 Oct 23;393(2):478-95. doi: 10.1016/j.jmb.2009.08.020. Epub 2009 Aug 14.

PMID:
19683535
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Neuralized: regulating notch by putting away delta.

Krämer H.

Dev Cell. 2001 Dec;1(6):725-6.

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The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta.

Lai EC, Roegiers F, Qin X, Jan YN, Rubin GM.

Development. 2005 May;132(10):2319-32. Epub 2005 Apr 13.

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Genome engineering-based analysis of Bearded family genes reveals both functional redundancy and a nonessential function in lateral inhibition in Drosophila.

Chanet S, Vodovar N, Mayau V, Schweisguth F.

Genetics. 2009 Aug;182(4):1101-8. doi: 10.1534/genetics.109.105023. Epub 2009 Jun 15.

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Both inhibition and activation of Notch signaling rely on a conserved Neuralized-binding motif in Bearded proteins and the Notch ligand Delta.

Fontana JR, Posakony JW.

Dev Biol. 2009 Sep 15;333(2):373-85. doi: 10.1016/j.ydbio.2009.06.039. Epub 2009 Jul 4.

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neuralized Encodes a peripheral membrane protein involved in delta signaling and endocytosis.

Pavlopoulos E, Pitsouli C, Klueg KM, Muskavitch MA, Moschonas NK, Delidakis C.

Dev Cell. 2001 Dec;1(6):807-16.

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Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells.

Overstreet E, Fitch E, Fischer JA.

Development. 2004 Nov;131(21):5355-66. Epub 2004 Oct 6.

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Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1.

Koutelou E, Sato S, Tomomori-Sato C, Florens L, Swanson SK, Washburn MP, Kokkinaki M, Conaway RC, Conaway JW, Moschonas NK.

J Biol Chem. 2008 Feb 15;283(7):3846-53. Epub 2007 Dec 12.

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Neuralized functions cell autonomously to regulate Drosophila sense organ development.

Yeh E, Zhou L, Rudzik N, Boulianne GL.

EMBO J. 2000 Sep 1;19(17):4827-37.

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