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Items: 1 to 20 of 454

1.

Pregnane X receptor: molecular basis for species differences in CYP3A induction by xenobiotics.

LeCluyse EL.

Chem Biol Interact. 2001 May 16;134(3):283-9. Review.

PMID:
11336976
2.

Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation.

Zhang H, LeCulyse E, Liu L, Hu M, Matoney L, Zhu W, Yan B.

Arch Biochem Biophys. 1999 Aug 1;368(1):14-22.

PMID:
10415106
3.

Humanized xenobiotic response in mice expressing nuclear receptor SXR.

Xie W, Barwick JL, Downes M, Blumberg B, Simon CM, Nelson MC, Neuschwander-Tetri BA, Brunt EM, Guzelian PS, Evans RM.

Nature. 2000 Jul 27;406(6794):435-9.

PMID:
10935643
4.

Induction of cytochrome P450 3A by paclitaxel in mice: pivotal role of the nuclear xenobiotic receptor, pregnane X receptor.

Nallani SC, Goodwin B, Maglich JM, Buckley DJ, Buckley AR, Desai PB.

Drug Metab Dispos. 2003 May;31(5):681-4.

5.

Effect of prototypical inducing agents on P-glycoprotein and CYP3A expression in mouse tissues.

Matheny CJ, Ali RY, Yang X, Pollack GM.

Drug Metab Dispos. 2004 Sep;32(9):1008-14.

6.

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution.

Jones SA, Moore LB, Shenk JL, Wisely GB, Hamilton GA, McKee DD, Tomkinson NC, LeCluyse EL, Lambert MH, Willson TM, Kliewer SA, Moore JT.

Mol Endocrinol. 2000 Jan;14(1):27-39.

PMID:
10628745
7.

Use of the nuclear receptor PXR to predict drug interactions.

Moore JT, Kliewer SA.

Toxicology. 2000 Nov 16;153(1-3):1-10. Review.

PMID:
11090943
8.

Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction.

Bertilsson G, Heidrich J, Svensson K, Asman M, Jendeberg L, Sydow-B├Ąckman M, Ohlsson R, Postlind H, Blomquist P, Berkenstam A.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12208-13.

9.

CAR and PXR expression and inducibility of CYP2B and CYP3A activities in rat and rabbit lungs.

Chirulli V, Longo V, Marini S, Mazzaccaro A, Fiorio R, Gervasi PG.

Life Sci. 2005 Apr 15;76(22):2535-46.

PMID:
15769478
10.

The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants.

Zhang J, Kuehl P, Green ED, Touchman JW, Watkins PB, Daly A, Hall SD, Maurel P, Relling M, Brimer C, Yasuda K, Wrighton SA, Hancock M, Kim RB, Strom S, Thummel K, Russell CG, Hudson JR Jr, Schuetz EG, Boguski MS.

Pharmacogenetics. 2001 Oct;11(7):555-72.

PMID:
11668216
11.

Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.

Staudinger J, Liu Y, Madan A, Habeebu S, Klaassen CD.

Drug Metab Dispos. 2001 Nov;29(11):1467-72.

12.
13.

Rabbit pregnane X receptor is activated by rifampicin.

Savas U, Wester MR, Griffin KJ, Johnson EF.

Drug Metab Dispos. 2000 May;28(5):529-37.

14.

Expression of PXR, CYP3A and MDR1 genes in liver of zebrafish.

Bresolin T, de Freitas Rebelo M, Celso Dias Bainy A.

Comp Biochem Physiol C Toxicol Pharmacol. 2005 Mar-Apr;140(3-4):403-7.

PMID:
15914091
15.

Endocrine disruptors induce cytochrome P450 by affecting transcriptional regulation via pregnane X receptor.

Mikamo E, Harada S, Nishikawa J, Nishihara T.

Toxicol Appl Pharmacol. 2003 Nov 15;193(1):66-72.

PMID:
14613717
16.

Induction of CYP3A expression by dehydroepiandrosterone: involvement of the pregnane X receptor.

Ripp SL, Fitzpatrick JL, Peters JM, Prough RA.

Drug Metab Dispos. 2002 May;30(5):570-5.

17.

Relative receptor expression is a determinant in xenobiotic-mediated CYP3A induction in rat and human cells.

Swales K, Plant N, Ayrton A, Hood S, Gibson G.

Xenobiotica. 2003 Jul;33(7):703-16.

PMID:
12893520
19.

Rat PXR reporter-gene activity correlates with the induction of CYP3A in rat precision-cut liver slices.

Cui X, Thomas A, Montgomery D, Gu C, Morrison RA, White RE, Cheng KC.

Comb Chem High Throughput Screen. 2005 Jun;8(4):341-6.

PMID:
16101010
20.

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