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11329460,10875803,10473516,15242948,16943346,16861643,15606613,17005929,23518075,12438379,12010994,15184408,18329343,18692540,9874655,16145098,15908383,22005585,18979999,20668139,19413883,17881504,21806401,22301696,28331078,22691409,20592155,15910992,16426005,22391021,26577191,10875801,21411245,16490705,15681078,28487230,15059788,11336278,12296851,18519559,34331511,29695323,12667217,16540176,23365203,24173026,17671227,15137490,17154047,20926697,17916110,26512049,18339431,35835806,11943331,15539508,18977269,11463225,16045732,11687445,21440314,12447766,10972905,16326043,26320985,12933831,16734114,16760317,20719984,20022773,17499400,15541793,26375813,30029900,12853392,18337375,21852544,15501751,22419675,23707076,10992489,17502400,31780694,16428796,23475045,25180583,25110654,12904381,10816479,15102752,25107461,17033714,27615603,25855555,22718125,26060998,9714409,20219883,33323658,23925885,30827373,15972546,28168855,12002425,24132602,26425695,14653340,29155877,19587150,15297485,20880640,12734217,24394444,7493774,24204624,12782055,30243373,27167122,12713896,18400977,28072845,19389081,21712953,12441800,30305467,10970372,16760322,3307732,27863556,10548589,16603624,11278121,25136958,24679958,24636301,24378586,33872473,29145844,25695736,33536465,2034894,14573662,27450013,9199424,35570041,12965934,10883854,8557334,29559101,26949166,19641628,35777280,30327211,26884103,8934651,1585626,15102765,11700926,10889408,23523102,23986315,2191012,23425597,12654816,11438135,36857964,31954316,28888636,21918115,21062483,25855362,23565211,16425998,10992526,31328169,21935486,19575746,7525483,9640240,7824893,14723623,7521095,28978510,1615636,24794136,32259815,15358642,33281817,16372884,10603390,18815611,19605596,23251517,15939747,10702486,15824420,26544594,24374737,15784562,12213334,8073620,10438049,26906942,12628767,26267100,24908189,18281626,23300440,26108287,24636303,23038072,19467342,14573663,28610788,3528377,14623166,29560355,21526117,31437738,20086089,25991696,7491820,11285116,12410828,33418045,10564555,7507889,9466778,9784542,11856587,34490387,15784584,10768946,328424,25138291,809031,23707003,17194810,18927068,9129098,19641100,11083835,28115506,31972498,1882133,25620706,19129468,31383314,26549366,12034543,22237891,19135497,29050772,21197095,23595504,29408038,2646701,28126017,11288518,18254982,35784315,11696195,32892112,8298518,3055660,24119726,28404571,24768355,9723778,23136116,18032595,3278986,33321133,8533313,31846797,23000594,27833091,12758201,7822025,17328725,30636533,11500410,34335572,8556509,19486308,23417080,28387329,36425039,11895982,34368285,11137264,28592322,2649053,1604242,2413162,29197526,20458447,35498753,35952489,23287127,8777966,8890902,24478485,26677202,7915446,23691171,10024540,14511237,1909047,374015,27358463,29343690,29170044,9220581,9746617,24532066,34479106,7746959,18362135,29866255,1691265,32793643,9529066,9846755,28903115,30417002,33230112,11480420,9766228,8128186,818022,31340991,12496181,8934653,35852636,34494864,28007592,14715573,14576908,8900072,9569495,396918,12781479,10085056,20090020,15872224,12641651,12814702,11337137,24008694,34604367,22719207,30349823,36215871,2643563,33917739,28686691,33116165,31750773,9692182,9673239,10948169,7018487,9387238,16682085,22322353,30502913,26679799,9453632,28348866,35565515,24741280,23419946,22870206,1711006,9632623,7790072,15780438,25464825,17698194,31138110,20450075,11083825,35889984,16458757,19729059,15633050,32768870,17644438,26553300,11309158,7765849,4875430,19424492,4270816,23808561,28689009,7009047,26092385,23988278,29129226,12753776,10812229,17906795,26251056,26690346,25550244,336017,3056744,4609908,19649364,11598095,33166313,4568897,16916959,780276,11158363,26518735,33782422,797673,18077619,3553003,29312328,8734641,11463240,18486627,13743247,28372590,31378264,9172438,25737829,23326525,26999334,9553708,18579695,20049086,18375799,12093684,35030535,7009046,7803935,12400866,36293113,9066108,7822037,19926028,4598114,31831701,26346536,26657720,2488347,25071781,24586655,34314936,30955344,25664343,36425598,32984254,36590473,32549360,7699061,26989718,34617184,68806,8073628,22589585,30596774,16131654,8807210,23484118,28428950,768991,29983863,14905032,2197602,35775552,4966002,6785233,23616670,26070398,31712604,28043570,2276618,33055304,34773437,31117936,30151368,6389525,8807512,8828213,28043591,4857796,15438397,8762861,1464353,36496897,33529917,5711561,13286857,9861836,22701814,25324841,28934697,33392283,29163649,29998129,14410870,14139546,13082388,13905379,3541887,3536755,13367323,27432469,23516200,12379740,3538372,779671,12517764,33430286,23545302,14932270,34822619,27959391,13918370,24293440,808863,15417250,3887743,28424454,4918400,29855554,32322376,14104122,29094040,4875429,15414402,15409749,13773277,32370415,9402852,15437970,5891429,25013134,5949221,2900952,26564042,14932271,29556853,14426049,36977236,13820557,13254176,14777740,29142508,16558010,15430869,24031527,32987977,34746449,13780230,13522252,13328750,26543108,13328751,27103721,17337611,14781680,14787365,1383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Use of synthetic peptides derived from the antigens ESAT-6 and CFP-10 for differential diagnosis of bovine tuberculosis in cattle.

Vordermeier HM, Whelan A, Cockle PJ, Farrant L, Palmer N, Hewinson RG. Vordermeier HM, et al. Clin Diagn Lab Immunol. 2001 May;8(3):571-8. doi: 10.1128/CDLI.8.3.571-578.2001. Clin Diagn Lab Immunol. 2001. PMID: 11329460 Free PMC article.

Toward the development of diagnostic assays to discriminate between Mycobacterium bovis infection and bacille Calmette-Guérin vaccination in cattle.

Vordermeier HM, Cockle PJ, Whelan AO, Rhodes S, Hewinson RG. Vordermeier HM, et al. Clin Infect Dis. 2000 Jun;30 Suppl 3:S291-8. doi: 10.1086/313877. Clin Infect Dis. 2000. PMID: 10875803

Development of diagnostic reagents to differentiate between Mycobacterium bovis BCG vaccination and M. bovis infection in cattle.

Vordermeier HM, Cockle PC, Whelan A, Rhodes S, Palmer N, Bakker D, Hewinson RG. Vordermeier HM, et al. Clin Diagn Lab Immunol. 1999 Sep;6(5):675-82. doi: 10.1128/CDLI.6.5.675-682.1999. Clin Diagn Lab Immunol. 1999. PMID: 10473516 Free PMC article.

Use of recombinant ESAT-6:CFP-10 fusion protein for differentiation of infections of cattle by Mycobacterium bovis and by M. avium subsp. avium and M. avium subsp. paratuberculosis.

Waters WR, Nonnecke BJ, Palmer MV, Robbe-Austermann S, Bannantine JP, Stabel JR, Whipple DL, Payeur JB, Estes DM, Pitzer JE, Minion FC. Waters WR, et al. Clin Diagn Lab Immunol. 2004 Jul;11(4):729-35. doi: 10.1128/CDLI.11.4.729-735.2004. Clin Diagn Lab Immunol. 2004. PMID: 15242948 Free PMC article.

Field evaluation of a novel differential diagnostic reagent for detection of Mycobacterium bovis in cattle.

Cockle PJ, Gordon SV, Hewinson RG, Vordermeier HM. Cockle PJ, et al. Clin Vaccine Immunol. 2006 Oct;13(10):1119-24. doi: 10.1128/CVI.00209-06. Epub 2006 Aug 30. Clin Vaccine Immunol. 2006. PMID: 16943346 Free PMC article.

Immunogenicity of Mycobacterium tuberculosis antigens in Mycobacterium bovis BCG-vaccinated and M. bovis-infected cattle.

Mustafa AS, Skeiky YA, Al-Attiyah R, Alderson MR, Hewinson RG, Vordermeier HM. Mustafa AS, et al. Infect Immun. 2006 Aug;74(8):4566-72. doi: 10.1128/IAI.01660-05. Infect Immun. 2006. PMID: 16861643 Free PMC article.

Vaccination of neonatal calves with Mycobacterium bovis BCG induces protection against intranasal challenge with virulent M. bovis.

Hope JC, Thom ML, Villarreal-Ramos B, Vordermeier HM, Hewinson RG, Howard CJ. Hope JC, et al. Clin Exp Immunol. 2005 Jan;139(1):48-56. doi: 10.1111/j.1365-2249.2005.02668.x. Clin Exp Immunol. 2005. PMID: 15606613 Free PMC article.

Flow cytometric detection of gamma interferon can effectively discriminate Mycobacterium bovis BCG-vaccinated cattle from M. bovis-infected cattle.

Sopp P, Howard CJ, Hope JC. Sopp P, et al. Clin Vaccine Immunol. 2006 Dec;13(12):1343-8. doi: 10.1128/CVI.00291-06. Epub 2006 Sep 27. Clin Vaccine Immunol. 2006. PMID: 17005929 Free PMC article.

Mycobacterium bovis Δmce2 double deletion mutant protects cattle against challenge with virulent M. bovis.

Blanco FC, Bianco MV, Garbaccio S, Meikle V, Gravisaco MJ, Montenegro V, Alfonseca E, Singh M, Barandiaran S, Canal A, Vagnoni L, Buddle BM, Bigi F, Cataldi A. Blanco FC, et al. Tuberculosis (Edinb). 2013 May;93(3):363-72. doi: 10.1016/j.tube.2013.02.004. Epub 2013 Mar 19. Tuberculosis (Edinb). 2013. PMID: 23518075 Clinical Trial.

Identification of novel Mycobacterium tuberculosis antigens with potential as diagnostic reagents or subunit vaccine candidates by comparative genomics.

Cockle PJ, Gordon SV, Lalvani A, Buddle BM, Hewinson RG, Vordermeier HM. Cockle PJ, et al. Infect Immun. 2002 Dec;70(12):6996-7003. doi: 10.1128/IAI.70.12.6996-7003.2002. Infect Immun. 2002. PMID: 12438379 Free PMC article.

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