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Items: 1 to 20 of 69

1.

The transcriptional corepressor NAB2 blocks Egr-1-mediated growth factor activation and angiogenesis.

Houston P, Campbell CJ, Svaren J, Milbrandt J, Braddock M.

Biochem Biophys Res Commun. 2001 May 4;283(2):480-6.

PMID:
11327726
2.

NAB2, a corepressor of EGR-1, inhibits vascular endothelial growth factor-mediated gene induction and angiogenic responses of endothelial cells.

Lucerna M, Mechtcheriakova D, Kadl A, Schabbauer G, Schäfer R, Gruber F, Koshelnick Y, Müller HD, Issbrücker K, Clauss M, Binder BR, Hofer E.

J Biol Chem. 2003 Mar 28;278(13):11433-40. Epub 2002 Nov 8.

3.
4.

Egr-1 induces the expression of its corepressor nab2 by activation of the nab2 promoter thereby establishing a negative feedback loop.

Kumbrink J, Gerlinger M, Johnson JP.

J Biol Chem. 2005 Dec 30;280(52):42785-93. Epub 2005 Oct 31.

7.
8.

Hepatocyte growth factor/scatter factor differentially regulates expression of proangiogenic factors through Egr-1 in head and neck squamous cell carcinoma.

Worden B, Yang XP, Lee TL, Bagain L, Yeh NT, Cohen JG, Van Waes C, Chen Z.

Cancer Res. 2005 Aug 15;65(16):7071-80.

9.
10.

Chlamydia pneumoniae induces tissue factor expression in mouse macrophages via activation of Egr-1 and the MEK-ERK1/2 pathway.

Bea F, Puolakkainen MH, McMillen T, Hudson FN, Mackman N, Kuo CC, Campbell LA, Rosenfeld ME.

Circ Res. 2003 Mar 7;92(4):394-401. Epub 2003 Feb 6.

11.

Stretch-inducible expression of the angiogenic factor CCN1 in vascular smooth muscle cells is mediated by Egr-1.

Grote K, Bavendiek U, Grothusen C, Flach I, Hilfiker-Kleiner D, Drexler H, Schieffer B.

J Biol Chem. 2004 Dec 31;279(53):55675-81. Epub 2004 Oct 18.

12.

NSAIDs inhibit the activation of egr-1 gene in microvascular endothelial cells. A key to inhibition of angiogenesis?

Szabó IL, Pai R, Soreghan B, Jones MK, Baatar D, Kawanaka H, Tarnawski AS.

J Physiol Paris. 2001 Jan-Dec;95(1-6):379-83.

PMID:
11595463
13.

Modulation of early growth response (EGR) transcription factor-dependent gene expression by using recombinant adenovirus.

Ehrengruber MU, Muhlebach SG, Söhrman S, Leutenegger CM, Lester HA, Davidson N.

Gene. 2000 Nov 27;258(1-2):63-9.

PMID:
11111043
14.

Induction of early growth-response factor 1 by platelet-derived growth factor in human airway smooth muscle.

Hjoberg J, Le L, Imrich A, Subramaniam V, Mathew SI, Vallone J, Haley KJ, Green FH, Shore SA, Silverman ES.

Am J Physiol Lung Cell Mol Physiol. 2004 Apr;286(4):L817-25.

15.

Angiotensin II-induced transcriptional activation of the cyclin D1 gene is mediated by Egr-1 in CHO-AT(1A) cells.

Guillemot L, Levy A, Raymondjean M, Rothhut B.

J Biol Chem. 2001 Oct 19;276(42):39394-403. Epub 2001 Aug 13.

16.

Vascular smooth muscle cells express the transcriptional corepressor NAB2 in response to injury.

Silverman ES, Khachigian LM, Santiago FS, Williams AJ, Lindner V, Collins T.

Am J Pathol. 1999 Oct;155(4):1311-7.

17.

Induction of tissue factor expression in human endothelial cells by CD40 ligand is mediated via activator protein 1, nuclear factor kappa B, and Egr-1.

Bavendiek U, Libby P, Kilbride M, Reynolds R, Mackman N, Schönbeck U.

J Biol Chem. 2002 Jul 12;277(28):25032-9. Epub 2002 Apr 26.

18.

Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1beta.

Tan L, Peng H, Osaki M, Choy BK, Auron PE, Sandell LJ, Goldring MB.

J Biol Chem. 2003 May 16;278(20):17688-700. Epub 2003 Mar 11.

19.

Epidermal-growth-factor-induced proliferation of astrocytes requires Egr transcription factors.

Mayer SI, Rössler OG, Endo T, Charnay P, Thiel G.

J Cell Sci. 2009 Sep 15;122(Pt 18):3340-50. doi: 10.1242/jcs.048272. Epub 2009 Aug 25.

20.

Transcription factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth.

Fahmy RG, Dass CR, Sun LQ, Chesterman CN, Khachigian LM.

Nat Med. 2003 Aug;9(8):1026-32. Epub 2003 Jul 20.

PMID:
12872165

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