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Efficacy of zanamivir against avian influenza A viruses that possess genes encoding H5N1 internal proteins and are pathogenic in mammals.

Leneva IA, Goloubeva O, Fenton RJ, Tisdale M, Webster RG.

Antimicrob Agents Chemother. 2001 Apr;45(4):1216-24.


Comparison of efficacies of RWJ-270201, zanamivir, and oseltamivir against H5N1, H9N2, and other avian influenza viruses.

Govorkova EA, Leneva IA, Goloubeva OG, Bush K, Webster RG.

Antimicrob Agents Chemother. 2001 Oct;45(10):2723-32.


Inhibition of influenza virus infections in mice by GS4104, an orally effective influenza virus neuraminidase inhibitor.

Sidwell RW, Huffman JH, Barnard DL, Bailey KW, Wong MH, Morrison A, Syndergaard T, Kim CU.

Antiviral Res. 1998 Feb;37(2):107-20.


Virulence may determine the necessary duration and dosage of oseltamivir treatment for highly pathogenic A/Vietnam/1203/04 influenza virus in mice.

Yen HL, Monto AS, Webster RG, Govorkova EA.

J Infect Dis. 2005 Aug 15;192(4):665-72. Epub 2005 Jul 15.


Characterization of the influenza A virus gene pool in avian species in southern China: was H6N1 a derivative or a precursor of H5N1?

Hoffmann E, Stech J, Leneva I, Krauss S, Scholtissek C, Chin PS, Peiris M, Shortridge KF, Webster RG.

J Virol. 2000 Jul;74(14):6309-15.


Molecular characterization of H9N2 influenza viruses: were they the donors of the "internal" genes of H5N1 viruses in Hong Kong?

Guan Y, Shortridge KF, Krauss S, Webster RG.

Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9363-7.


H9N2 influenza viruses possessing H5N1-like internal genomes continue to circulate in poultry in southeastern China.

Guan Y, Shortridge KF, Krauss S, Chin PS, Dyrting KC, Ellis TM, Webster RG, Peiris M.

J Virol. 2000 Oct;74(20):9372-80.


Establishment of influenza A virus (H6N1) in minor poultry species in southern China.

Cheung CL, Vijaykrishna D, Smith GJ, Fan XH, Zhang JX, Bahl J, Duan L, Huang K, Tai H, Wang J, Poon LL, Peiris JS, Chen H, Guan Y.

J Virol. 2007 Oct;81(19):10402-12. Epub 2007 Jul 25.


Efficacy of the new neuraminidase inhibitor CS-8958 against H5N1 influenza viruses.

Kiso M, Kubo S, Ozawa M, Le QM, Nidom CA, Yamashita M, Kawaoka Y.

PLoS Pathog. 2010 Feb 26;6(2):e1000786. doi: 10.1371/journal.ppat.1000786.


Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza.

Macdonald SJ, Cameron R, Demaine DA, Fenton RJ, Foster G, Gower D, Hamblin JN, Hamilton S, Hart GJ, Hill AP, Inglis GG, Jin B, Jones HT, McConnell DB, McKimm-Breschkin J, Mills G, Nguyen V, Owens IJ, Parry N, Shanahan SE, Smith D, Watson KG, Wu WY, Tucker SP.

J Med Chem. 2005 Apr 21;48(8):2964-71.


Oral administration of a prodrug of the influenza virus neuraminidase inhibitor GS 4071 protects mice and ferrets against influenza infection.

Mendel DB, Tai CY, Escarpe PA, Li W, Sidwell RW, Huffman JH, Sweet C, Jakeman KJ, Merson J, Lacy SA, Lew W, Williams MA, Zhang L, Chen MS, Bischofberger N, Kim CU.

Antimicrob Agents Chemother. 1998 Mar;42(3):640-6.


In vitro and in vivo efficacy of fluorodeoxycytidine analogs against highly pathogenic avian influenza H5N1, seasonal, and pandemic H1N1 virus infections.

Kumaki Y, Day CW, Smee DF, Morrey JD, Barnard DL.

Antiviral Res. 2011 Nov;92(2):329-40. doi: 10.1016/j.antiviral.2011.09.001. Epub 2011 Sep 8.


Highly potent and long-acting trimeric and tetrameric inhibitors of influenza virus neuraminidase.

Watson KG, Cameron R, Fenton RJ, Gower D, Hamilton S, Jin B, Krippner GY, Luttick A, McConnell D, MacDonald SJ, Mason AM, Nguyen V, Tucker SP, Wu WY.

Bioorg Med Chem Lett. 2004 Mar 22;14(6):1589-92.


Evaluation of live attenuated influenza a virus h6 vaccines in mice and ferrets.

Chen Z, Santos C, Aspelund A, Gillim-Ross L, Jin H, Kemble G, Subbarao K.

J Virol. 2009 Jan;83(1):65-72. doi: 10.1128/JVI.01775-08. Epub 2008 Oct 22.

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