Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 250

1.

Dual inactivation of RB and p53 pathways in RAS-induced melanomas.

Bardeesy N, Bastian BC, Hezel A, Pinkel D, DePinho RA, Chin L.

Mol Cell Biol. 2001 Mar;21(6):2144-53.

2.

Genetic dissection of melanoma pathways in the mouse.

Yang FC, Merlino G, Chin L.

Semin Cancer Biol. 2001 Jun;11(3):261-8. Review.

PMID:
11407950
3.

Somatic p16(INK4a) loss accelerates melanomagenesis.

Monahan KB, Rozenberg GI, Krishnamurthy J, Johnson SM, Liu W, Bradford MK, Horner J, Depinho RA, Sharpless NE.

Oncogene. 2010 Oct 28;29(43):5809-17. doi: 10.1038/onc.2010.314. Epub 2010 Aug 9.

4.

Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence.

Zou X, Ray D, Aziyu A, Christov K, Boiko AD, Gudkov AV, Kiyokawa H.

Genes Dev. 2002 Nov 15;16(22):2923-34.

5.

Resistance of primary cultured mouse hepatic tumor cells to cellular senescence despite expression of p16(Ink4a), p19(Arf), p53, and p21(Waf1/Cip1).

Obata M, Imamura E, Yoshida Y, Goto J, Kishibe K, Yasuda A, Ogawa K.

Mol Carcinog. 2001 Sep;32(1):9-18.

PMID:
11568971
6.
7.

P16(INK4A) is implicated in both the immediate and adaptative response of human keratinocytes to UVB irradiation.

Chazal M, Marionnet C, Michel L, Mollier K, Dazard JE, Della Valle V, Larsen CJ, Gras MP, Basset-Séguin N.

Oncogene. 2002 Apr 18;21(17):2652-61.

8.

Both products of the mouse Ink4a/Arf locus suppress melanoma formation in vivo.

Sharpless NE, Kannan K, Xu J, Bosenberg MW, Chin L.

Oncogene. 2003 Aug 7;22(32):5055-9.

PMID:
12902988
9.
10.

Mutational analysis of selected genes in the TGFbeta, Wnt, pRb, and p53 pathways in primary uveal melanoma.

Edmunds SC, Kelsell DP, Hungerford JL, Cree IA.

Invest Ophthalmol Vis Sci. 2002 Sep;43(9):2845-51.

PMID:
12202501
11.

The INK4a/ARF tumor suppressor: one gene--two products--two pathways.

Chin L, Pomerantz J, DePinho RA.

Trends Biochem Sci. 1998 Aug;23(8):291-6. Review.

PMID:
9757829
12.
13.

Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation.

Lin AW, Lowe SW.

Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5025-30. Epub 2001 Apr 17.

14.

Profiles of the 2 INK4a gene products, p16 and p14ARF, in human reference urothelium and bladder carcinomas, according to pRb and p53 protein status.

Le Frère-Belda MA, Gil Diez de Medina S, Daher A, Martin N, Albaud B, Heudes D, Abbou CC, Thiery JP, Zafrani ES, Radvanyi F, Chopin D.

Hum Pathol. 2004 Jul;35(7):817-24.

PMID:
15257544
15.

The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence.

Haferkamp S, Tran SL, Becker TM, Scurr LL, Kefford RF, Rizos H.

Aging (Albany NY). 2009 May 16;1(6):542-56.

16.

Components of the Rb pathway are critical targets of UV mutagenesis in a murine melanoma model.

Kannan K, Sharpless NE, Xu J, O'Hagan RC, Bosenberg M, Chin L.

Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1221-5. Epub 2003 Jan 21.

17.

Multigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis.

Güner D, Sturm I, Hemmati P, Hermann S, Hauptmann S, Wurm R, Budach V, Dörken B, Lorenz M, Daniel PT.

Int J Cancer. 2003 Feb 10;103(4):445-54.

18.
19.

Genetic and epigenetic alterations in lung tumors from bitransgenic Ki-rasG12C expressing mice.

Floyd HS, Jennings-Gee JE, Kock ND, Miller MS.

Mol Carcinog. 2006 Jul;45(7):506-17.

PMID:
16482519
20.

The inhibitor of cyclin-dependent kinase 4a/alternative reading frame (INK4a/ARF) locus encoded proteins p16INK4a and p19ARF repress cyclin D1 transcription through distinct cis elements.

D'Amico M, Wu K, Fu M, Rao M, Albanese C, Russell RG, Lian H, Bregman D, White MA, Pestell RG.

Cancer Res. 2004 Jun 15;64(12):4122-30.

Supplemental Content

Support Center