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Items: 1 to 20 of 198


Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor.

Vang T, Torgersen KM, Sundvold V, Saxena M, Levy FO, Skålhegg BS, Hansson V, Mustelin T, Taskén K.

J Exp Med. 2001 Feb 19;193(4):497-507.


Removal of C-terminal SRC kinase from the immune synapse by a new binding protein.

Rahmouni S, Vang T, Alonso A, Williams S, van Stipdonk M, Soncini C, Moutschen M, Schoenberger SP, Mustelin T.

Mol Cell Biol. 2005 Mar;25(6):2227-41.


Knockdown of C-terminal Src kinase by siRNA-mediated RNA interference augments T cell receptor signaling in mature T cells.

Vang T, Abrahamsen H, Myklebust S, Enserink J, Prydz H, Mustelin T, Amarzguioui M, Tasken K.

Eur J Immunol. 2004 Aug;34(8):2191-9.


Combined spatial and enzymatic regulation of Csk by cAMP and protein kinase a inhibits T cell receptor signaling.

Vang T, Abrahamsen H, Myklebust S, Horejsí V, Taskén K.

J Biol Chem. 2003 May 16;278(20):17597-600. Epub 2003 Mar 28.


Spatiotemporal control of cyclic AMP immunomodulation through the PKA-Csk inhibitory pathway is achieved by anchoring to an Ezrin-EBP50-PAG scaffold in effector T cells.

Cornez I, Taskén K.

FEBS Lett. 2010 Jun 18;584(12):2681-8. doi: 10.1016/j.febslet.2010.04.056. Epub 2010 Apr 24. Review.


Protein kinase A intersects SRC signaling in membrane microdomains.

Abrahamsen H, Vang T, Taskén K.

J Biol Chem. 2003 May 9;278(19):17170-7. Epub 2003 Feb 26.


Cyclic AMP-mediated immune regulation--overview of mechanisms of action in T cells.

Mosenden R, Taskén K.

Cell Signal. 2011 Jun;23(6):1009-16. doi: 10.1016/j.cellsig.2010.11.018. Epub 2010 Dec 2. Review.


Differential regulation of T cell receptor-mediated Th1 cell IFN-gamma production and proliferation by divergent cAMP-mediated redox pathways.

Cochrane R, Clark RB, Huang CK, Cone RE.

J Interferon Cytokine Res. 2001 Oct;21(10):797-807.


Cannabinoid receptor type 1- and 2-mediated increase in cyclic AMP inhibits T cell receptor-triggered signaling.

Börner C, Smida M, Höllt V, Schraven B, Kraus J.

J Biol Chem. 2009 Dec 18;284(51):35450-60. doi: 10.1074/jbc.M109.006338.


Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts.

Torgersen KM, Vang T, Abrahamsen H, Yaqub S, Horejsí V, Schraven B, Rolstad B, Mustelin T, Taskén K.

J Biol Chem. 2001 Aug 3;276(31):29313-8. Epub 2001 Jun 4.


Cross talk between phosphatidylinositol 3-kinase and cyclic AMP (cAMP)-protein kinase a signaling pathways at the level of a protein kinase B/beta-arrestin/cAMP phosphodiesterase 4 complex.

Bjørgo E, Solheim SA, Abrahamsen H, Baillie GS, Brown KM, Berge T, Okkenhaug K, Houslay MD, Taskén K.

Mol Cell Biol. 2010 Apr;30(7):1660-72. doi: 10.1128/MCB.00696-09. Epub 2010 Jan 19.


Cutting edge: Fyn is essential for tyrosine phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells.

Yasuda K, Nagafuku M, Shima T, Okada M, Yagi T, Yamada T, Minaki Y, Kato A, Tani-Ichi S, Hamaoka T, Kosugi A.

J Immunol. 2002 Sep 15;169(6):2813-7.


Targeting of CD45 protein tyrosine phosphatase activity to lipid microdomains on the T cell surface inhibits TCR signaling.

He X, Woodford-Thomas TA, Johnson KG, Shah DD, Thomas ML.

Eur J Immunol. 2002 Sep;32(9):2578-87.


Rosmarinic acid inhibits TCR-induced T cell activation and proliferation in an Lck-dependent manner.

Won J, Hur YG, Hur EM, Park SH, Kang MA, Choi Y, Park C, Lee KH, Yun Y.

Eur J Immunol. 2003 Apr;33(4):870-9.


Zinc differentially regulates mitogen-activated protein kinases in human T cells.

Hönscheid A, Dubben S, Rink L, Haase H.

J Nutr Biochem. 2012 Jan;23(1):18-26. doi: 10.1016/j.jnutbio.2010.10.007. Epub 2011 Feb 17.


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