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A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery.

Marcotrigiano J, Lomakin IB, Sonenberg N, Pestova TV, Hellen CU, Burley SK.

Mol Cell. 2001 Jan;7(1):193-203.


Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G.

Marcotrigiano J, Gingras AC, Sonenberg N, Burley SK.

Mol Cell. 1999 Jun;3(6):707-16.


Two structurally atypical HEAT domains in the C-terminal portion of human eIF4G support binding to eIF4A and Mnk1.

Bellsolell L, Cho-Park PF, Poulin F, Sonenberg N, Burley SK.

Structure. 2006 May;14(5):913-23.


Wheat eukaryotic initiation factor 4B organizes assembly of RNA and eIFiso4G, eIF4A, and poly(A)-binding protein.

Cheng S, Gallie DR.

J Biol Chem. 2006 Aug 25;281(34):24351-64. Epub 2006 Jun 27.


RNA aptamers to mammalian initiation factor 4G inhibit cap-dependent translation by blocking the formation of initiation factor complexes.

Miyakawa S, Oguro A, Ohtsu T, Imataka H, Sonenberg N, Nakamura Y.

RNA. 2006 Oct;12(10):1825-34. Epub 2006 Aug 29.


Crystal structure of the middle domain of human poly(A)-binding protein-interacting protein 1.

Lei J, Mesters JR, von Brunn A, Hilgenfeld R.

Biochem Biophys Res Commun. 2011 May 20;408(4):680-5. doi: 10.1016/j.bbrc.2011.04.088. Epub 2011 Apr 23.


Eukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AII.

Li Q, Imataka H, Morino S, Rogers GW Jr, Richter-Cook NJ, Merrick WC, Sonenberg N.

Mol Cell Biol. 1999 Nov;19(11):7336-46.


Mutational analysis of the DEAD-box RNA helicase eIF4AII characterizes its interaction with transformation suppressor Pdcd4 and eIF4GI.

Zakowicz H, Yang HS, Stark C, Wlodawer A, Laronde-Leblanc N, Colburn NH.

RNA. 2005 Mar;11(3):261-74. Epub 2005 Jan 20.


Translation driven by an eIF4G core domain in vivo.

De Gregorio E, Preiss T, Hentze MW.

EMBO J. 1999 Sep 1;18(17):4865-74.


The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation.

Yang HS, Jansen AP, Komar AA, Zheng X, Merrick WC, Costes S, Lockett SJ, Sonenberg N, Colburn NH.

Mol Cell Biol. 2003 Jan;23(1):26-37.


Cocrystal structure of the messenger RNA 5' cap-binding protein (eIF4E) bound to 7-methyl-GDP.

Marcotrigiano J, Gingras AC, Sonenberg N, Burley SK.

Cell. 1997 Jun 13;89(6):951-61.

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