Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 125


The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis.

Siegfried G, Basak A, Cromlish JA, Benjannet S, Marcinkiewicz J, Chrétien M, Seidah NG, Khatib AM.

J Clin Invest. 2003 Jun;111(11):1723-32.


Processing of the Ebola virus glycoprotein by the proprotein convertase furin.

Volchkov VE, Feldmann H, Volchkova VA, Klenk HD.

Proc Natl Acad Sci U S A. 1998 May 12;95(10):5762-7.


Comparative functional role of PC7 and furin in the processing of the HIV envelope glycoprotein gp160.

Decroly E, Benjannet S, Savaria D, Seidah NG.

FEBS Lett. 1997 Mar 17;405(1):68-72.


A fluorogenic peptide containing the processing site of human SARS corona virus S-protein: kinetic evaluation and NMR structure elucidation.

Basak A, Mitra A, Basak S, Pasko C, Chrétien M, Seaton P.

Chembiochem. 2007 Jun 18;8(9):1029-37.


The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity.

Zhong M, Munzer JS, Basak A, Benjannet S, Mowla SJ, Decroly E, Chrétien M, Seidah NG.

J Biol Chem. 1999 Nov 26;274(48):33913-20.


Processing specificity and biosynthesis of the Drosophila melanogaster convertases dfurin1, dfurin1-CRR, dfurin1-X, and dfurin2.

De Bie I, Savaria D, Roebroek AJ, Day R, Lazure C, Van de Ven WJ, Seidah NG.

J Biol Chem. 1995 Jan 20;270(3):1020-8.


Implication of the proprotein convertases in iron homeostasis: proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin.

Guillemot J, Canuel M, Essalmani R, Prat A, Seidah NG.

Hepatology. 2013 Jun;57(6):2514-24. doi: 10.1002/hep.26297. Epub 2013 May 15.


Histidine-rich human salivary peptides are inhibitors of proprotein convertases furin and PC7 but act as substrates for PC1.

Basak A, Ernst B, Brewer D, Seidah NG, Munzer JS, Lazure C, Lajoie GA.

J Pept Res. 1997 Jun;49(6):596-603.


Proteolytic activation of respiratory syncytial virus fusion protein. Cleavage at two furin consensus sequences.

Zimmer G, Budz L, Herrler G.

J Biol Chem. 2001 Aug 24;276(34):31642-50. Epub 2001 Jun 19.


Targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens.

Shiryaev SA, Remacle AG, Ratnikov BI, Nelson NA, Savinov AY, Wei G, Bottini M, Rega MF, Parent A, Desjardins R, Fugere M, Day R, Sabet M, Pellecchia M, Liddington RC, Smith JW, Mustelin T, Guiney DG, Lebl M, Strongin AY.

J Biol Chem. 2007 Jul 20;282(29):20847-53. Epub 2007 May 30.


Processing of alpha4 integrin by the proprotein convertases: histidine at position P6 regulates cleavage.

Bergeron E, Basak A, Decroly E, Seidah NG.

Biochem J. 2003 Jul 15;373(Pt 2):475-84.


In vitro characterization of the novel proprotein convertase PC7.

Munzer JS, Basak A, Zhong M, Mamarbachi A, Hamelin J, Savaria D, Lazure C, Hendy GN, Benjannet S, Chrétien M, Seidah NG.

J Biol Chem. 1997 Aug 8;272(32):19672-81. Erratum in: J Biol Chem 1997 Nov 28;272(48):30589.


Processing of viral glycoproteins by the subtilisin-like endoprotease furin and its inhibition by specific peptidylchloroalkylketones.

Garten W, Hallenberger S, Ortmann D, Schäfer W, Vey M, Angliker H, Shaw E, Klenk HD.

Biochimie. 1994;76(3-4):217-25. Review.


Furin and proprotein convertase 7 (PC7)/lymphoma PC endogenously expressed in rat liver can be resolved into distinct post-Golgi compartments.

Wouters S, Leruth M, Decroly E, Vandenbranden M, Creemers JW, van de Loo JW, Ruysschaert JM, Courtoy PJ.

Biochem J. 1998 Dec 1;336 ( Pt 2):311-6.


Supplemental Content

Support Center