Similar articles for PMID: 11158755

Year	Number of Results
1985	1
1987	1
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1998	3
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2000	11
2001	14
2002	15
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2014	4
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2016	11
2017	4
2018	4
2019	4
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2022	6
2023	1
2024	0

1

Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor.

Clements JM, Beckett RP, Brown A, Catlin G, Lobell M, Palan S, Thomas W, Whittaker M, Wood S, Salama S, Baker PJ, Rodgers HF, Barynin V, Rice DW, Hunter MG. Clements JM, et al. Antimicrob Agents Chemother. 2001 Feb;45(2):563-70. doi: 10.1128/AAC.45.2.563-570.2001. Antimicrob Agents Chemother. 2001. PMID: 11158755 Free PMC article.

2

Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor.

Chen DZ, Patel DV, Hackbarth CJ, Wang W, Dreyer G, Young DC, Margolis PS, Wu C, Ni ZJ, Trias J, White RJ, Yuan Z. Chen DZ, et al. Biochemistry. 2000 Feb 15;39(6):1256-62. doi: 10.1021/bi992245y. Biochemistry. 2000. PMID: 10684604

3

Asymmetric synthesis of BB-3497--a potent peptide deformylase inhibitor.

Pratt LM, Beckett RP, Davies SJ, Launchbury SB, Miller A, Spavold ZM, Todd RS, Whittaker M. Pratt LM, et al. Bioorg Med Chem Lett. 2001 Oct 8;11(19):2585-8. doi: 10.1016/s0960-894x(01)00509-1. Bioorg Med Chem Lett. 2001. PMID: 11551755

4

Novel approaches to antimicrobial therapy: peptide deformylase.

Waller AS, Clements JM. Waller AS, et al. Curr Opin Drug Discov Devel. 2002 Sep;5(5):785-92. Curr Opin Drug Discov Devel. 2002. PMID: 12630299 Review.

5

Synthesis and antibacterial activity of peptide deformylase inhibitors.

Huntington KM, Yi T, Wei Y, Pei D. Huntington KM, et al. Biochemistry. 2000 Apr 18;39(15):4543-51. doi: 10.1021/bi992452y. Biochemistry. 2000. PMID: 10758004

6

Peptide deformylase in Staphylococcus aureus: resistance to inhibition is mediated by mutations in the formyltransferase gene.

Margolis PS, Hackbarth CJ, Young DC, Wang W, Chen D, Yuan Z, White R, Trias J. Margolis PS, et al. Antimicrob Agents Chemother. 2000 Jul;44(7):1825-31. doi: 10.1128/AAC.44.7.1825-1831.2000. Antimicrob Agents Chemother. 2000. PMID: 10858337 Free PMC article.

7

N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity.

Hackbarth CJ, Chen DZ, Lewis JG, Clark K, Mangold JB, Cramer JA, Margolis PS, Wang W, Koehn J, Wu C, Lopez S, Withers G 3rd, Gu H, Dunn E, Kulathila R, Pan SH, Porter WL, Jacobs J, Trias J, Patel DV, Weidmann B, White RJ, Yuan Z. Hackbarth CJ, et al. Antimicrob Agents Chemother. 2002 Sep;46(9):2752-64. doi: 10.1128/AAC.46.9.2752-2764.2002. Antimicrob Agents Chemother. 2002. PMID: 12183225 Free PMC article.

8

Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.

Apfel C, Banner DW, Bur D, Dietz M, Hirata T, Hubschwerlen C, Locher H, Page MG, Pirson W, Rossé G, Specklin JL. Apfel C, et al. J Med Chem. 2000 Jun 15;43(12):2324-31. doi: 10.1021/jm000018k. J Med Chem. 2000. PMID: 10882358

9

Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group.

Smith HK, Beckett RP, Clements JM, Doel S, East SP, Launchbury SB, Pratt LM, Spavold ZM, Thomas W, Todd RS, Whittaker M. Smith HK, et al. Bioorg Med Chem Lett. 2002 Dec 16;12(24):3595-9. doi: 10.1016/s0960-894x(02)00790-4. Bioorg Med Chem Lett. 2002. PMID: 12443784

10

Resistance of Streptococcus pneumoniae to deformylase inhibitors is due to mutations in defB.

Margolis P, Hackbarth C, Lopez S, Maniar M, Wang W, Yuan Z, White R, Trias J. Margolis P, et al. Antimicrob Agents Chemother. 2001 Sep;45(9):2432-5. doi: 10.1128/AAC.45.9.2432-2435.2001. Antimicrob Agents Chemother. 2001. PMID: 11502510 Free PMC article.

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