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Items: 1 to 20 of 143

1.

MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells.

Garrington TP, Ishizuka T, Papst PJ, Chayama K, Webb S, Yujiri T, Sun W, Sather S, Russell DM, Gibson SB, Keller G, Gelfand EW, Johnson GL.

EMBO J. 2000 Oct 16;19(20):5387-95.

2.

Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells.

Chayama K, Papst PJ, Garrington TP, Pratt JC, Ishizuka T, Webb S, Ganiatsas S, Zon LI, Sun W, Johnson GL, Gelfand EW.

Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4599-604. Epub 2001 Mar 27.

3.

Stem cell factor augments Fc epsilon RI-mediated TNF-alpha production and stimulates MAP kinases via a different pathway in MC/9 mast cells.

Ishizuka T, Kawasome H, Terada N, Takeda K, Gerwins P, Keller GM, Johnson GL, Gelfand EW.

J Immunol. 1998 Oct 1;161(7):3624-30.

4.
5.

MEF2C regulates c-Jun but not TNF-alpha gene expression in stimulated mast cells.

Wei X, Sun W, Fan R, Hahn J, Joetham A, Li G, Webb S, Garrington T, Dakhama A, Lucas J, Johnson GL, Gelfand EW.

Eur J Immunol. 2003 Oct;33(10):2903-9.

6.

MEKK2 regulates the coordinate activation of ERK5 and JNK in response to FGF-2 in fibroblasts.

Kesavan K, Lobel-Rice K, Sun W, Lapadat R, Webb S, Johnson GL, Garrington TP.

J Cell Physiol. 2004 Apr;199(1):140-8.

PMID:
14978743
8.

Mast cell tumor necrosis factor alpha production is regulated by MEK kinases.

Ishizuka T, Terada N, Gerwins P, Hamelmann E, Oshiba A, Fanger GR, Johnson GL, Gelfand EW.

Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6358-63.

9.

Aggregation of the FcepsilonRI on mast cells stimulates c-Jun amino-terminal kinase activity. A response inhibited by wortmannin.

Ishizuka T, Oshiba A, Sakata N, Terada N, Johnson GL, Gelfand EW.

J Biol Chem. 1996 May 31;271(22):12762-6.

10.

Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis.

Hammaker DR, Boyle DL, Chabaud-Riou M, Firestein GS.

J Immunol. 2004 Feb 1;172(3):1612-8.

12.

MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression.

Su B, Cheng J, Yang J, Guo Z.

J Biol Chem. 2001 May 4;276(18):14784-90. Epub 2001 Feb 6.

14.
15.

Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors.

Whitmarsh AJ, Yang SH, Su MS, Sharrocks AD, Davis RJ.

Mol Cell Biol. 1997 May;17(5):2360-71.

16.

Mutations in protein kinase subdomain X differentially affect MEKK2 and MEKK1 activity.

Huang J, Tu Z, Lee FS.

Biochem Biophys Res Commun. 2003 Apr 4;303(2):532-40.

PMID:
12659851
17.

Inhibition of Kit expression by IL-4 and IL-10 in murine mast cells: role of STAT6 and phosphatidylinositol 3'-kinase.

Mirmonsef P, Shelburne CP, Fitzhugh Yeatman C 2nd, Chong HJ, Ryan JJ.

J Immunol. 1999 Sep 1;163(5):2530-9.

19.

MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway.

Sun W, Kesavan K, Schaefer BC, Garrington TP, Ware M, Johnson NL, Gelfand EW, Johnson GL.

J Biol Chem. 2001 Feb 16;276(7):5093-100. Epub 2000 Nov 9.

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