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Regulation of macropinocytosis by p21-activated kinase-1.

Dharmawardhane S, Schürmann A, Sells MA, Chernoff J, Schmid SL, Bokoch GM.

Mol Biol Cell. 2000 Oct;11(10):3341-52.


Localization of p21-activated kinase 1 (PAK1) to pinocytic vesicles and cortical actin structures in stimulated cells.

Dharmawardhane S, Sanders LC, Martin SS, Daniels RH, Bokoch GM.

J Cell Biol. 1997 Sep 22;138(6):1265-78.


Temporal and spatial distribution of activated Pak1 in fibroblasts.

Sells MA, Pfaff A, Chernoff J.

J Cell Biol. 2000 Dec 25;151(7):1449-58.


Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells.

Sells MA, Knaus UG, Bagrodia S, Ambrose DM, Bokoch GM, Chernoff J.

Curr Biol. 1997 Mar 1;7(3):202-10.


alphaPix stimulates p21-activated kinase activity through exchange factor-dependent and -independent mechanisms.

Daniels RH, Zenke FT, Bokoch GM.

J Biol Chem. 1999 Mar 5;274(10):6047-50. Erratum in: J Biol Chem 1999 May 21;274(21):15292.


p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts.

Sells MA, Boyd JT, Chernoff J.

J Cell Biol. 1999 May 17;145(4):837-49.


Uptake of advanced glycation end products by proximal tubule epithelial cells via macropinocytosis.

Gallicchio MA, Bach LA.

Biochim Biophys Acta. 2013 Dec;1833(12):2922-32. doi: 10.1016/j.bbamcr.2013.05.024. Epub 2013 Jun 6.


BetaPix-enhanced p38 activation by Cdc42/Rac/PAK/MKK3/6-mediated pathway. Implication in the regulation of membrane ruffling.

Lee SH, Eom M, Lee SJ, Kim S, Park HJ, Park D.

J Biol Chem. 2001 Jul 6;276(27):25066-72. Epub 2001 Apr 17.


AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter.

Cai D, Iyer A, Felekkis KN, Near RI, Luo Z, Chernoff J, Albanese C, Pestell RG, Lerner A.

Cancer Res. 2003 Oct 15;63(20):6802-8.


A GTPase-independent mechanism of p21-activated kinase activation. Regulation by sphingosine and other biologically active lipids.

Bokoch GM, Reilly AM, Daniels RH, King CC, Olivera A, Spiegel S, Knaus UG.

J Biol Chem. 1998 Apr 3;273(14):8137-44.


Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics.

Edwards DC, Sanders LC, Bokoch GM, Gill GN.

Nat Cell Biol. 1999 Sep;1(5):253-9.


Activation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cells.

Jung ID, Lee J, Lee KB, Park CG, Kim YK, Seo DW, Park D, Lee HW, Han JW, Lee HY.

Eur J Biochem. 2004 Apr;271(8):1557-65.


Dynein light chain 1 phosphorylation controls macropinocytosis.

Yang Z, Vadlamudi RK, Kumar R.

J Biol Chem. 2005 Jan 7;280(1):654-9. Epub 2004 Oct 24.


Localization of p21-activated kinase 1 (PAK1) to pseudopodia, membrane ruffles, and phagocytic cups in activated human neutrophils.

Dharmawardhane S, Brownson D, Lennartz M, Bokoch GM.

J Leukoc Biol. 1999 Sep;66(3):521-7.


Analysis of small GTPase signaling pathways using p21-activated kinase mutants that selectively couple to Cdc42.

Reeder MK, Serebriiskii IG, Golemis EA, Chernoff J.

J Biol Chem. 2001 Nov 2;276(44):40606-13. Epub 2001 Aug 20.


Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1.

Frost JA, Swantek JL, Stippec S, Yin MJ, Gaynor R, Cobb MH.

J Biol Chem. 2000 Jun 30;275(26):19693-9.


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