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Items: 1 to 20 of 226

1.
2.

Aging, chromatin, and food restriction--connecting the dots.

Campisi J.

Science. 2000 Sep 22;289(5487):2062-3. Erratum in: Science 2000 Nov 3;290(5493):936c.

PMID:
11032557
3.

Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration.

Lin SJ, Kaeberlein M, Andalis AA, Sturtz LA, Defossez PA, Culotta VC, Fink GR, Guarente L.

Nature. 2002 Jul 18;418(6895):344-8.

PMID:
12124627
4.

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase.

Imai S, Armstrong CM, Kaeberlein M, Guarente L.

Nature. 2000 Feb 17;403(6771):795-800.

PMID:
10693811
5.

Sound silencing: the Sir2 protein and cellular senescence.

Defossez PA, Lin SJ, McNabb DS.

Bioessays. 2001 Apr;23(4):327-32. Review.

PMID:
11268038
6.

High osmolarity extends life span in Saccharomyces cerevisiae by a mechanism related to calorie restriction.

Kaeberlein M, Andalis AA, Fink GR, Guarente L.

Mol Cell Biol. 2002 Nov;22(22):8056-66.

7.

HST2 mediates SIR2-independent life-span extension by calorie restriction.

Lamming DW, Latorre-Esteves M, Medvedik O, Wong SN, Tsang FA, Wang C, Lin SJ, Sinclair DA.

Science. 2005 Sep 16;309(5742):1861-4. Epub 2005 Jul 28.

8.
9.

Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction".

Kaeberlein M, Steffen KK, Hu D, Dang N, Kerr EO, Tsuchiya M, Fields S, Kennedy BK.

Science. 2006 Jun 2;312(5778):1312; author reply 1312.

10.

Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins.

Smith DL Jr, McClure JM, Matecic M, Smith JS.

Aging Cell. 2007 Oct;6(5):649-62. Epub 2007 Aug 15.

11.

Distinct roles of processes modulated by histone deacetylases Rpd3p, Hda1p, and Sir2p in life extension by caloric restriction in yeast.

Jiang JC, Wawryn J, Shantha Kumara HM, Jazwinski SM.

Exp Gerontol. 2002 Aug-Sep;37(8-9):1023-30.

PMID:
12213553
12.

Vitamins and aging: pathways to NAD+ synthesis.

Denu JM.

Cell. 2007 May 4;129(3):453-4.

13.

Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+.

Belenky P, Racette FG, Bogan KL, McClure JM, Smith JS, Brenner C.

Cell. 2007 May 4;129(3):473-84.

14.

Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast.

Tsuchiya M, Dang N, Kerr EO, Hu D, Steffen KK, Oakes JA, Kennedy BK, Kaeberlein M.

Aging Cell. 2006 Dec;5(6):505-14.

15.

Longevity research. Single signal unites treatments that prolong life.

Strauss E.

Science. 2003 May 9;300(5621):881-3. No abstract available.

PMID:
12738822
16.

Gene silencing: two faces of SIR2.

Gottschling DE.

Curr Biol. 2000 Oct 5;10(19):R708-11. Review.

17.
18.

An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing.

Tanny JC, Dowd GJ, Huang J, Hilz H, Moazed D.

Cell. 1999 Dec 23;99(7):735-45.

19.

The Sir2 protein family: A novel deacetylase for gene silencing and more.

Shore D.

Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14030-2. Review. No abstract available.

20.

Analysis of Sir2p domains required for rDNA and telomeric silencing in Saccharomyces cerevisiae.

Cockell MM, Perrod S, Gasser SM.

Genetics. 2000 Mar;154(3):1069-83. Erratum in: Genetics 2000 Aug;155(4):following 2020.

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