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Items: 1 to 20 of 348

1.

Site-specific expression of transferrin receptor by human colon cancer cells directly correlates with eradication by antitransferrin recombinant immunotoxin.

Shinohara H, Fan D, Ozawa S, Yano S, Van Arsdell M, Viner JL, Beers R, Pastan I, Fidler IJ.

Int J Oncol. 2000 Oct;17(4):643-51.

PMID:
10995873
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The recombinant immunotoxin anti-Tac(Fv)-Pseudomonas exotoxin 40 is cytotoxic toward peripheral blood malignant cells from patients with adult T-cell leukemia.

Kreitman RJ, Chaudhary VK, Waldmann T, Willingham MC, FitzGerald DJ, Pastan I.

Proc Natl Acad Sci U S A. 1990 Nov;87(21):8291-5.

5.

Expression of HER2 in human gastric cancer cells directly correlates with antitumor activity of a recombinant disulfide-stabilized anti-HER2 immunotoxin.

Shinohara H, Morita S, Kawai M, Miyamoto A, Sonoda T, Pastan I, Tanigawa N.

J Surg Res. 2002 Feb;102(2):169-77.

PMID:
11796015
6.

Immunotoxins made with a recombinant form of Pseudomonas exotoxin A that do not require proteolysis for activity.

Theuer CP, Kreitman RJ, FitzGerald DJ, Pastan I.

Cancer Res. 1993 Jan 15;53(2):340-7.

9.

In vitro and in vivo characterization of BR96 sFv-PE40. A single-chain immunotoxin fusion protein that cures human breast carcinoma xenografts in athymic mice and rats.

Siegall CB, Chace D, Mixan B, Garrigues U, Wan H, Paul L, Wolff E, Hellström I, Hellström KE.

J Immunol. 1994 Mar 1;152(5):2377-84.

PMID:
8133048
11.

The in vitro antitumor effect and in vivo tumor-specificity distribution of human-mouse chimeric antibody against transferrin receptor.

Qing Y, Shuo W, Zhihua W, Huifen Z, Ping L, Lijiang L, Xiaorong Z, Liming C, Daiwen X, Yu H, Wei X, Min F, Zuohua F, Guanxin S.

Cancer Immunol Immunother. 2006 Sep;55(9):1111-21. Epub 2005 Dec 8.

PMID:
16341531
12.
13.

Antitumor effects of B3-PE and B3-LysPE40 in a nude mouse model of human breast cancer and the evaluation of B3-PE toxicity in monkeys.

Pai LH, Batra JK, FitzGerald DJ, Willingham MC, Pastan I.

Cancer Res. 1992 Jun 1;52(11):3189-93.

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Preclinical evaluation of a recombinant anti-prostate specific membrane antigen single-chain immunotoxin against prostate cancer.

Wolf P, Alt K, Wetterauer D, Bühler P, Gierschner D, Katzenwadel A, Wetterauer U, Elsässer-Beile U.

J Immunother. 2010 Apr;33(3):262-71. doi: 10.1097/CJI.0b013e3181c5495c.

PMID:
20445346
17.

Antitumor activity of fibroblast growth factor receptor 3-specific immunotoxins in a xenograft mouse model of bladder carcinoma is mediated by apoptosis.

Martínez-Torrecuadrada JL, Cheung LH, López-Serra P, Barderas R, Cañamero M, Ferreiro S, Rosenblum MG, Casal JI.

Mol Cancer Ther. 2008 Apr;7(4):862-73. doi: 10.1158/1535-7163.MCT-07-0394.

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19.

B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice.

Brinkmann U, Pai LH, FitzGerald DJ, Willingham M, Pastan I.

Proc Natl Acad Sci U S A. 1991 Oct 1;88(19):8616-20.

20.

Recombinant anti-EGFR immunotoxin 425(scFv)-ETA' demonstrates anti-tumor activity against disseminated human pancreatic cancer in nude mice.

Bruell D, Bruns CJ, Yezhelyev M, Huhn M, Müller J, Ischenko I, Fischer R, Finnern R, Jauch KW, Barth S.

Int J Mol Med. 2005 Feb;15(2):305-13.

PMID:
15647848

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