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Items: 1 to 20 of 68

1.

The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila.

Scanga SE, Ruel L, Binari RC, Snow B, Stambolic V, Bouchard D, Peters M, Calvieri B, Mak TW, Woodgett JR, Manoukian AS.

Oncogene. 2000 Aug 17;19(35):3971-7.

2.

DJ-1, a novel regulator of the tumor suppressor PTEN.

Kim RH, Peters M, Jang Y, Shi W, Pintilie M, Fletcher GC, DeLuca C, Liepa J, Zhou L, Snow B, Binari RC, Manoukian AS, Bray MR, Liu FF, Tsao MS, Mak TW.

Cancer Cell. 2005 Mar;7(3):263-73.

3.

Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene.

Gil EB, Malone Link E, Liu LX, Johnson CD, Lees JA.

Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2925-30.

4.

Modulation of cellular apoptotic potential: contributions to oncogenesis.

Stambolic V, Mak TW, Woodgett JR.

Oncogene. 1999 Nov 1;18(45):6094-103. Review.

5.

Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB.

Stocker H, Andjelkovic M, Oldham S, Laffargue M, Wymann MP, Hemmings BA, Hafen E.

Science. 2002 Mar 15;295(5562):2088-91. Epub 2002 Feb 28.

6.

Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster.

Miron M, Lasko P, Sonenberg N.

Mol Cell Biol. 2003 Dec;23(24):9117-26.

7.

Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway.

Goberdhan DC, Paricio N, Goodman EC, Mlodzik M, Wilson C.

Genes Dev. 1999 Dec 15;13(24):3244-58.

8.
9.

Lilliputian: an AF4/FMR2-related protein that controls cell identity and cell growth.

Wittwer F, van der Straten A, Keleman K, Dickson BJ, Hafen E.

Development. 2001 Mar;128(5):791-800.

10.

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN.

Stambolic V, Suzuki A, de la Pompa JL, Brothers GM, Mirtsos C, Sasaki T, Ruland J, Penninger JM, Siderovski DP, Mak TW.

Cell. 1998 Oct 2;95(1):29-39.

11.

PI3K/PTEN/AKT pathway. A critical mediator of oncogenic signaling.

Paez J, Sellers WR.

Cancer Treat Res. 2003;115:145-67. Review. No abstract available.

PMID:
12613196
13.

PI3K/Akt and apoptosis: size matters.

Franke TF, Hornik CP, Segev L, Shostak GA, Sugimoto C.

Oncogene. 2003 Dec 8;22(56):8983-98. Review.

PMID:
14663477
14.

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway.

Sun H, Lesche R, Li DM, Liliental J, Zhang H, Gao J, Gavrilova N, Mueller B, Liu X, Wu H.

Proc Natl Acad Sci U S A. 1999 May 25;96(11):6199-204.

15.

Loss of PTEN expression leading to high Akt activation in human multiple myelomas.

Hyun T, Yam A, Pece S, Xie X, Zhang J, Miki T, Gutkind JS, Li W.

Blood. 2000 Nov 15;96(10):3560-8.

16.

Insulin hypersensitivity and resistance to streptozotocin-induced diabetes in mice lacking PTEN in adipose tissue.

Kurlawalla-Martinez C, Stiles B, Wang Y, Devaskar SU, Kahn BB, Wu H.

Mol Cell Biol. 2005 Mar;25(6):2498-510.

18.
19.

Phosphoinositide signaling in urological disease.

Theodorescu D.

J Urol. 2003 Jun;169(6):2394-6. No abstract available.

PMID:
12771804
20.

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

Verdu J, Buratovich MA, Wilder EL, Birnbaum MJ.

Nat Cell Biol. 1999 Dec;1(8):500-6.

PMID:
10587646

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