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Items: 1 to 20 of 443

1.

CTLA-4 (CD152) can inhibit T cell activation by two different mechanisms depending on its level of cell surface expression.

Carreno BM, Bennett F, Chau TA, Ling V, Luxenberg D, Jussif J, Baroja ML, Madrenas J.

J Immunol. 2000 Aug 1;165(3):1352-6.

2.

Interaction of CTLA-4 (CD152) with CD80 or CD86 inhibits human T-cell activation.

Vandenborre K, Van Gool SW, Kasran A, Ceuppens JL, Boogaerts MA, Vandenberghe P.

Immunology. 1999 Nov;98(3):413-21.

3.

Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiation.

Tao X, Constant S, Jorritsma P, Bottomly K.

J Immunol. 1997 Dec 15;159(12):5956-63.

PMID:
9550393
4.

Cutting edge: tyrosine-independent transmission of inhibitory signals by CTLA-4.

Cinek T, Sadra A, Imboden JB.

J Immunol. 2000 Jan 1;164(1):5-8.

5.

Chimeric co-stimulatory molecules that selectively act through CD28 or CTLA-4 on human T cells.

Lazetic S, Leong SR, Chang JC, Ong R, Dawes G, Punnonen J.

J Biol Chem. 2002 Oct 11;277(41):38660-8. Epub 2002 Aug 6.

6.

Differential role of CTLA-4 in regulation of resting memory versus naive CD4 T cell activation.

Metz DP, Farber DL, Taylor T, Bottomly K.

J Immunol. 1998 Dec 1;161(11):5855-61.

7.

CD28/CTLA-4 and CD80/CD86 families: signaling and function.

Slavik JM, Hutchcroft JE, Bierer BE.

Immunol Res. 1999;19(1):1-24. Review.

PMID:
10374692
8.

Critical role of costimulation in the activation of naive antigen-specific TCR transgenic CD8+ T cells in vitro.

Chai JG, Vendetti S, Bartok I, Schoendorf D, Takacs K, Elliott J, Lechler R, Dyson J.

J Immunol. 1999 Aug 1;163(3):1298-305.

9.

Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4.

Kearney ER, Walunas TL, Karr RW, Morton PA, Loh DY, Bluestone JA, Jenkins MK.

J Immunol. 1995 Aug 1;155(3):1032-6.

PMID:
7543510
10.

Interference with CD28, CD80, CD86 or CD152 in collagen-induced arthritis. Limited role of IFN-gamma in anti-B7-mediated suppression of disease.

Tellander AC, Pettersson U, Runström A, Andersson M, Michaëlsson E.

J Autoimmun. 2001 Aug;17(1):39-50.

PMID:
11488636
11.

Induction of T cell anergy in the absence of CTLA-4/B7 interaction.

Frauwirth KA, Alegre ML, Thompson CB.

J Immunol. 2000 Mar 15;164(6):2987-93.

12.

The inhibitory function of CTLA-4 does not require its tyrosine phosphorylation.

Baroja ML, Luxenberg D, Chau T, Ling V, Strathdee CA, Carreno BM, Madrenas J.

J Immunol. 2000 Jan 1;164(1):49-55.

13.

Detection of a novel specificity (CTLA-4) in ATG/TMG globulins and sera from ATG-treated leukemic patients.

Pistillo MP, Tazzari PL, Bonifazi F, Bandini G, Kato T, Matsui T, Nishioka K, Conte R, Ferrara GB.

Transplantation. 2002 Apr 27;73(8):1295-302.

PMID:
11981425
14.

ICOS costimulation requires IL-2 and can be prevented by CTLA-4 engagement.

Riley JL, Blair PJ, Musser JT, Abe R, Tezuka K, Tsuji T, June CH.

J Immunol. 2001 Apr 15;166(8):4943-8.

15.

CTLA-4 (CD152) inhibits the specific lysis mediated by human cytolytic T lymphocytes in a clonally distributed fashion.

Saverino D, Tenca C, Zarcone D, Merlo A, Megiovanni AM, Valle MT, Manca F, Grossi CE, Ciccone E.

J Immunol. 1999 Jan 15;162(2):651-8.

16.
17.

B7 interactions with CD28 and CTLA-4 control tolerance or induction of mucosal inflammation in chronic experimental colitis.

Liu Z, Geboes K, Hellings P, Maerten P, Heremans H, Vandenberghe P, Boon L, van Kooten P, Rutgeerts P, Ceuppens JL.

J Immunol. 2001 Aug 1;167(3):1830-8.

18.

The role of CTLA-4 in induction and maintenance of peripheral T cell tolerance.

Eagar TN, Karandikar NJ, Bluestone JA, Miller SD.

Eur J Immunol. 2002 Apr;32(4):972-81.

19.

The expanding world of co-stimulation: the two-signal model revisited.

Chambers CA.

Trends Immunol. 2001 Apr;22(4):217-23. Review.

PMID:
11274928
20.

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