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Items: 1 to 20 of 324

1.

Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice.

Ziyadeh FN, Hoffman BB, Han DC, Iglesias-De La Cruz MC, Hong SW, Isono M, Chen S, McGowan TA, Sharma K.

Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):8015-20.

3.

N-acetyl-seryl-aspartyl-lysyl-proline prevents renal insufficiency and mesangial matrix expansion in diabetic db/db mice.

Shibuya K, Kanasaki K, Isono M, Sato H, Omata M, Sugimoto T, Araki S, Isshiki K, Kashiwagi A, Haneda M, Koya D.

Diabetes. 2005 Mar;54(3):838-45.

4.

The renal TGF-beta system in the db/db mouse model of diabetic nephropathy.

Cohen MP, Sharma K, Guo J, Eltayeb BO, Ziyadeh FN.

Exp Nephrol. 1998 May-Jun;6(3):226-33.

PMID:
9639038
5.

Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis.

Riser BL, Denichilo M, Cortes P, Baker C, Grondin JM, Yee J, Narins RG.

J Am Soc Nephrol. 2000 Jan;11(1):25-38.

6.

Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes.

Koya D, Haneda M, Nakagawa H, Isshiki K, Sato H, Maeda S, Sugimoto T, Yasuda H, Kashiwagi A, Ways DK, King GL, Kikkawa R.

FASEB J. 2000 Mar;14(3):439-47.

7.

Reversibility of established diabetic glomerulopathy by anti-TGF-beta antibodies in db/db mice.

Chen S, Iglesias-de la Cruz MC, Jim B, Hong SW, Isono M, Ziyadeh FN.

Biochem Biophys Res Commun. 2003 Jan 3;300(1):16-22.

PMID:
12480514
8.

Prevention of decline in renal function in the diabetic db/db mouse.

Cohen MP, Clements RS, Cohen JA, Shearman CW.

Diabetologia. 1996 Mar;39(3):270-4.

PMID:
8721771
9.

Tranilast prevents the progression of experimental diabetic nephropathy through suppression of enhanced extracellular matrix gene expression.

Akahori H, Ota T, Torita M, Ando H, Kaneko S, Takamura T.

J Pharmacol Exp Ther. 2005 Aug;314(2):514-21. Epub 2005 Apr 27.

10.

Prevention of diabetic nephropathy in db/db mice with glycated albumin antagonists. A novel treatment strategy.

Cohen MP, Sharma K, Jin Y, Hud E, Wu VY, Tomaszewski J, Ziyadeh FN.

J Clin Invest. 1995 May;95(5):2338-45.

11.

The key role of the transforming growth factor-beta system in the pathogenesis of diabetic nephropathy.

Chen S, Hong SW, Iglesias-de la Cruz MC, Isono M, Casaretto A, Ziyadeh FN.

Ren Fail. 2001 May-Jul;23(3-4):471-81. Review.

PMID:
11499562
12.

Soluble betaglycan reduces renal damage progression in db/db mice.

Juárez P, Vilchis-Landeros MM, Ponce-Coria J, Mendoza V, Hernández-Pando R, Bobadilla NA, López-Casillas F.

Am J Physiol Renal Physiol. 2007 Jan;292(1):F321-9. Epub 2006 Sep 5.

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14.

Amelioration of long-term renal changes in obese type 2 diabetic mice by a neutralizing vascular endothelial growth factor antibody.

Flyvbjerg A, Dagnaes-Hansen F, De Vriese AS, Schrijvers BF, Tilton RG, Rasch R.

Diabetes. 2002 Oct;51(10):3090-4.

15.

SMP-534 ameliorates progression of glomerular fibrosis and urinary albumin in diabetic db/db mice.

Sugaru E, Nakagawa T, Ono-Kishino M, Nagamine J, Tokunaga T, Kitoh M, Hume WE, Nagata R, Taiji M.

Am J Physiol Renal Physiol. 2006 Apr;290(4):F813-20. Epub 2005 Nov 8.

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Upregulation of mesangial growth factor and extracellular matrix synthesis by advanced glycation end products via a receptor-mediated mechanism.

Pugliese G, Pricci F, Romeo G, Pugliese F, Mené P, Giannini S, Cresci B, Galli G, Rotella CM, Vlassara H, Di Mario U.

Diabetes. 1997 Nov;46(11):1881-7.

PMID:
9356040
19.

Alpha-lipoic acid attenuates hyperglycemia and prevents glomerular mesangial matrix expansion in diabetes.

Melhem MF, Craven PA, Liachenko J, DeRubertis FR.

J Am Soc Nephrol. 2002 Jan;13(1):108-16.

20.

Inhibiting albumin glycation attenuates dysregulation of VEGFR-1 and collagen IV subchain production and the development of renal insufficiency.

Cohen MP, Lautenslager GT, Hud E, Shea E, Wang A, Chen S, Shearman CW.

Am J Physiol Renal Physiol. 2007 Feb;292(2):F789-95. Epub 2006 Oct 3.

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