Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 141

1.

An efficient synthesis of the anti-asthmatic agent T-440: a selective N-alkylation of 2-pyridone.

Sugahara M, Moritani Y, Kuroda T, Kondo K, Shimadzu H, Ukita T.

Chem Pharm Bull (Tokyo). 2000 Apr;48(4):589-91.

PMID:
10783088
2.

Novel selective PDE IV inhibitors as antiasthmatic agents. Synthesis and biological activities of a series of 1-aryl-2,3-bis(hydroxymethyl)naphthalene lignans.

Iwasaki T, Kondo K, Kuroda T, Moritani Y, Yamagata S, Sugiura M, Kikkawa H, Kaminuma O, Ikezawa K.

J Med Chem. 1996 Jul 5;39(14):2696-704.

PMID:
8709099
3.

Magnesium coordination-directed n-selective stereospecific alkylation of 2-pyridones, carbamates, and amides using α-halocarboxylic acids.

Fang YQ, Bio MM, Hansen KB, Potter MS, Clausen A.

J Am Chem Soc. 2010 Nov 10;132(44):15525-7. doi: 10.1021/ja107709w.

PMID:
20958067
4.

Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 6. Structure-activity studies of orally bioavailable, 2-pyridone-containing peptidomimetics.

Dragovich PS, Prins TJ, Zhou R, Brown EL, Maldonado FC, Fuhrman SA, Zalman LS, Tuntland T, Lee CA, Patick AK, Matthews DA, Hendrickson TF, Kosa MB, Liu B, Batugo MR, Gleeson JP, Sakata SK, Chen L, Guzman MC, Meador JW 3rd, Ferre RA, Worland ST.

J Med Chem. 2002 Apr 11;45(8):1607-23.

PMID:
11931615
5.

Preparation of N-alkyl 2-pyridones via a lithium iodide promoted O- to N-alkyl migration: scope and mechanism.

Tasker SZ, Bosscher MA, Shandro CA, Lanni EL, Ryu KA, Snapper GS, Utter JM, Ellsworth BA, Anderson CE.

J Org Chem. 2012 Sep 21;77(18):8220-30. Epub 2012 Sep 12.

PMID:
22928642
6.

A pyridone analogue of traditional cannabinoids. A new class of selective ligands for the CB(2) receptor.

Huffman JW, Lu J, Hynd G, Wiley JL, Martin BR.

Bioorg Med Chem. 2001 Nov;9(11):2863-70.

PMID:
11597467
7.
8.

Facile one-pot synthesis of N-difluoromethyl-2-pyridone derivatives.

Ando M, Wada T, Sato N.

Org Lett. 2006 Aug 17;8(17):3805-8.

PMID:
16898822
9.
10.
11.

Design, synthesis, and crystal structure of selective 2-pyridone tissue factor VIIa inhibitors.

Parlow JJ, Kurumbail RG, Stegeman RA, Stevens AM, Stallings WC, South MS.

J Med Chem. 2003 Oct 23;46(22):4696-701.

PMID:
14561089
12.

Synthesis of some pyridone derivatives.

Dawood NT, Abdel-Gawad SM, Soliman FM.

Boll Chim Farm. 2001 May-Jun;140(3):149-54.

PMID:
11486604
13.

Synthesis of substituted N-benzyl pyridones via an O- to N-alkyl migration.

Lanni EL, Bosscher MA, Ooms BD, Shandro CA, Ellsworth BA, Anderson CE.

J Org Chem. 2008 Aug 15;73(16):6425-8. doi: 10.1021/jo800866w. Epub 2008 Jul 9.

PMID:
18610979
14.

Glycogen phosphorylase inhibitory effects of 2-oxo-1,2-dihydropyridin-3-yl amide derivatives.

Karis ND, Loughlin WA, Jenkins ID, Healy PC.

Bioorg Med Chem. 2009 Jul 1;17(13):4724-33. doi: 10.1016/j.bmc.2009.04.049. Epub 2009 May 3.

PMID:
19443226
15.

Synthesis and pharmacological characterization of functionalized 2-pyridones structurally related to the cardiotonic agent milrinone.

Fossa P, Menozzi G, Dorigo P, Floreani M, Mosti L.

Bioorg Med Chem. 2003 Nov 3;11(22):4749-59.

PMID:
14556790
16.

Direct alkenylation and alkylation of pyridone derivatives by Ni/AlMe(3) catalysis.

Nakao Y, Idei H, Kanyiva KS, Hiyama T.

J Am Chem Soc. 2009 Nov 11;131(44):15996-7. doi: 10.1021/ja907214t.

PMID:
19835373
17.

Synthetic entries to substituted bicyclic pyridones.

Cheng D, Croft L, Abdi M, Lightfoot A, Gallagher T.

Org Lett. 2007 Dec 6;9(25):5175-8. Epub 2007 Nov 14.

PMID:
17999509
18.

Synthesis and luminescent properties and theoretical investigation on electronic structure of nitrile-based 2-pyridone molecules.

Chen L, Liu X, Xu B, Sun C, Tao P.

Spectrochim Acta A Mol Biomol Spectrosc. 2011 Sep;79(5):1926-30. doi: 10.1016/j.saa.2011.05.092. Epub 2011 Jun 1.

PMID:
21689972
19.

A metathesis-based approach to the synthesis of 2-pyridones and pyridines.

Donohoe TJ, Fishlock LP, Procopiou PA.

Org Lett. 2008 Jan 17;10(2):285-8. Epub 2007 Dec 23.

PMID:
18154343
20.

Iromycins: a new family of pyridone metabolites from Streptomyces sp. II. Convergent total synthesis.

Shojaei H, Li-Böhmer Z, von Zezschwitz P.

J Org Chem. 2007 Jul 6;72(14):5091-7. Epub 2007 Jun 12.

PMID:
17564460

Supplemental Content

Support Center