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Transport of peptide-MHC class II complexes in developing dendritic cells.

Turley SJ, Inaba K, Garrett WS, Ebersold M, Unternaehrer J, Steinman RM, Mellman I.

Science. 2000 Apr 21;288(5465):522-7.


Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane.

Chow A, Toomre D, Garrett W, Mellman I.

Nature. 2002 Aug 29;418(6901):988-94.


MHC class II transport from lysosomal compartments to the cell surface is determined by stable peptide binding, but not by the cytosolic domains of the alpha- and beta-chains.

Théry C, Brachet V, Regnault A, Rescigno M, Ricciardi-Castagnoli P, Bonnerot C, Amigorena S.

J Immunol. 1998 Sep 1;161(5):2106-13.


The pathway for MHCII-mediated presentation of endogenous proteins involves peptide transport to the endo-lysosomal compartment.

Dani A, Chaudhry A, Mukherjee P, Rajagopal D, Bhatia S, George A, Bal V, Rath S, Mayor S.

J Cell Sci. 2004 Aug 15;117(Pt 18):4219-30.


Dendritic cells regulate exposure of MHC class II at their plasma membrane by oligoubiquitination.

van Niel G, Wubbolts R, Ten Broeke T, Buschow SI, Ossendorp FA, Melief CJ, Raposo G, van Balkom BW, Stoorvogel W.

Immunity. 2006 Dec;25(6):885-94.


The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli.

Inaba K, Turley S, Iyoda T, Yamaide F, Shimoyama S, Reis e Sousa C, Germain RN, Mellman I, Steinman RM.

J Exp Med. 2000 Mar 20;191(6):927-36.


Tetraspan microdomains distinct from lipid rafts enrich select peptide-MHC class II complexes.

Kropshofer H, Spindeldreher S, Röhn TA, Platania N, Grygar C, Daniel N, Wölpl A, Langen H, Horejsi V, Vogt AB.

Nat Immunol. 2002 Jan;3(1):61-8.


Developmental regulation of MHC class II transport in mouse dendritic cells.

Pierre P, Turley SJ, Gatti E, Hull M, Meltzer J, Mirza A, Inaba K, Steinman RM, Mellman I.

Nature. 1997 Aug 21;388(6644):787-92.


Regulated recruitment of MHC class II and costimulatory molecules to lipid rafts in dendritic cells.

Meyer zum Bueschenfelde CO, Unternaehrer J, Mellman I, Bottomly K.

J Immunol. 2004 Nov 15;173(10):6119-24.


CD1 molecules efficiently present antigen in immature dendritic cells and traffic independently of MHC class II during dendritic cell maturation.

Cao X, Sugita M, Van Der Wel N, Lai J, Rogers RA, Peters PJ, Brenner MB.

J Immunol. 2002 Nov 1;169(9):4770-7.


Antigen loading of MHC class I molecules in the endocytic tract.

Kleijmeer MJ, Escola JM, UytdeHaag FG, Jakobson E, Griffith JM, Osterhaus AD, Stoorvogel W, Melief CJ, Rabouille C, Geuze HJ.

Traffic. 2001 Feb;2(2):124-37.

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