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Items: 1 to 20 of 555

1.

Mapping the protein-DNA interface and the metal-binding site of the major human apurinic/apyrimidinic endonuclease.

Nguyen LH, Barsky D, Erzberger JP, Wilson DM 3rd.

J Mol Biol. 2000 May 5;298(3):447-59.

PMID:
10772862
3.
4.

Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism.

Beernink PT, Segelke BW, Hadi MZ, Erzberger JP, Wilson DM 3rd, Rupp B.

J Mol Biol. 2001 Apr 6;307(4):1023-34.

PMID:
11286553
5.
6.

Probing conformational changes in Ape1 during the progression of base excision repair.

Yu E, Gaucher SP, Hadi MZ.

Biochemistry. 2010 May 11;49(18):3786-96. doi: 10.1021/bi901828t.

PMID:
20377204
7.

XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions.

Vidal AE, Boiteux S, Hickson ID, Radicella JP.

EMBO J. 2001 Nov 15;20(22):6530-9.

9.

Intragenic suppression of an active site mutation in the human apurinic/apyrimidinic endonuclease.

Izumi T, Malecki J, Chaudhry MA, Weinfeld M, Hill JH, Lee JC, Mitra S.

J Mol Biol. 1999 Mar 19;287(1):47-57.

PMID:
10074406
11.

Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair.

Parker A, Gu Y, Mahoney W, Lee SH, Singh KK, Lu AL.

J Biol Chem. 2001 Feb 23;276(8):5547-55. Epub 2000 Nov 22.

12.
13.

Dynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and product.

Masuda Y, Bennett RA, Demple B.

J Biol Chem. 1998 Nov 13;273(46):30352-9.

15.

Rapid dissociation of human apurinic endonuclease (Ape1) from incised DNA induced by magnesium.

Masuda Y, Bennett RA, Demple B.

J Biol Chem. 1998 Nov 13;273(46):30360-5.

16.

DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected].

Mol CD, Izumi T, Mitra S, Tainer JA.

Nature. 2000 Jan 27;403(6768):451-6. Erratum in: Nature 2000 Mar 30;404(6777.

PMID:
10667800
17.

High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.

He H, Chen Q, Georgiadis MM.

Biochemistry. 2014 Oct 21;53(41):6520-9. doi: 10.1021/bi500676p. Epub 2014 Oct 8.

18.

Modulation of the 3'-->5'-exonuclease activity of human apurinic endonuclease (Ape1) by its 5'-incised Abasic DNA product.

Wong D, DeMott MS, Demple B.

J Biol Chem. 2003 Sep 19;278(38):36242-9. Epub 2003 Jul 10.

19.

Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes.

Tsutakawa SE, Shin DS, Mol CD, Izumi T, Arvai AS, Mantha AK, Szczesny B, Ivanov IN, Hosfield DJ, Maiti B, Pique ME, Frankel KA, Hitomi K, Cunningham RP, Mitra S, Tainer JA.

J Biol Chem. 2013 Mar 22;288(12):8445-55. doi: 10.1074/jbc.M112.422774. Epub 2013 Jan 25.

20.

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