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Items: 1 to 20 of 90

1.

Expression analysis of BACE2 in brain and peripheral tissues.

Bennett BD, Babu-Khan S, Loeloff R, Louis JC, Curran E, Citron M, Vassar R.

J Biol Chem. 2000 Jul 7;275(27):20647-51.

2.

Beta-secretase cleavage at amino acid residue 34 in the amyloid beta peptide is dependent upon gamma-secretase activity.

Shi XP, Tugusheva K, Bruce JE, Lucka A, Wu GX, Chen-Dodson E, Price E, Li Y, Xu M, Huang Q, Sardana MK, Hazuda DJ.

J Biol Chem. 2003 Jun 6;278(23):21286-94.

3.

Beta-amyloid secretases and beta-amloid degrading enzyme expression in lens.

Li G, Percontino L, Sun Q, Qazi AS, Frederikse PH.

Mol Vis. 2003 May 1;9:179-83.

4.
5.

ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase site.

Hussain I, Powell DJ, Howlett DR, Chapman GA, Gilmour L, Murdock PR, Tew DG, Meek TD, Chapman C, Schneider K, Ratcliffe SJ, Tattersall D, Testa TT, Southan C, Ryan DM, Simmons DL, Walsh FS, Dingwall C, Christie G.

Mol Cell Neurosci. 2000 Nov;16(5):609-19.

6.

BACE2 functions as an alternative alpha-secretase in cells.

Yan R, Munzner JB, Shuck ME, Bienkowski MJ.

J Biol Chem. 2001 Sep 7;276(36):34019-27.

7.

BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein.

Farzan M, Schnitzler CE, Vasilieva N, Leung D, Choe H.

Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9712-7.

8.

The gene encoding DRAP (BACE2), a glycosylated transmembrane protein of the aspartic protease family, maps to the down critical region.

Acquati F, Accarino M, Nucci C, Fumagalli P, Jovine L, Ottolenghi S, Taramelli R.

FEBS Lett. 2000 Feb 18;468(1):59-64.

9.

The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.

Stockley JH, O'Neill C.

Biochem Soc Trans. 2007 Jun;35(Pt 3):574-6. Review.

PMID:
17511655
10.

Quantification and distribution of beta-secretase alternative splice variants in the rat and human brain.

Zohar O, Cavallaro S, D'Agata V, Alkon DL.

Brain Res Mol Brain Res. 2003 Jul 4;115(1):63-8.

PMID:
12824056
11.

The beta-secretase, BACE: a prime drug target for Alzheimer's disease.

Vassar R.

J Mol Neurosci. 2001 Oct;17(2):157-70. Review.

PMID:
11816789
12.

A new aspartyl protease on 21q22.3, BACE2, is highly similar to Alzheimer's amyloid precursor protein beta-secretase.

Solans A, Estivill X, de La Luna S.

Cytogenet Cell Genet. 2000;89(3-4):177-84.

PMID:
10965118
13.

BACE1: the beta-secretase enzyme in Alzheimer's disease.

Vassar R.

J Mol Neurosci. 2004;23(1-2):105-14. Review.

PMID:
15126696
15.

Beta-secretase (BACE) as a drug target for Alzheimer's disease.

Vassar R.

Adv Drug Deliv Rev. 2002 Dec 7;54(12):1589-602. Review.

PMID:
12453676
17.

Substrate and inhibitor profile of BACE (beta-secretase) and comparison with other mammalian aspartic proteases.

Grüninger-Leitch F, Schlatter D, Küng E, Nelböck P, Döbeli H.

J Biol Chem. 2002 Feb 15;277(7):4687-93.

18.

Expression of beta-secretase mRNA in transgenic Tg2576 mouse brain with Alzheimer plaque pathology.

Bigl M, Apelt J, Luschekina EA, Lange-Dohna C, Rossner S, Schliebs R.

Neurosci Lett. 2000 Oct 6;292(2):107-10.

PMID:
10998560
19.

A splice variant of beta-secretase deficient in the amyloidogenic processing of the amyloid precursor protein.

Bodendorf U, Fischer F, Bodian D, Multhaup G, Paganetti P.

J Biol Chem. 2001 Apr 13;276(15):12019-23.

20.

Insights from modeling the tertiary structure of human BACE2.

Chou KC.

J Proteome Res. 2004 Sep-Oct;3(5):1069-72.

PMID:
15473697
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