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The hepatocyte nuclear factor 3 alpha gene, HNF3alpha (FOXA1), on chromosome band 14q13 is amplified and overexpressed in esophageal and lung adenocarcinomas.

Lin L, Miller CT, Contreras JI, Prescott MS, Dagenais SL, Wu R, Yee J, Orringer MB, Misek DE, Hanash SM, Glover TW, Beer DG.

Cancer Res. 2002 Sep 15;62(18):5273-9.


Amplification and overexpression of the dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) gene in esophageal and lung adenocarcinomas.

Miller CT, Aggarwal S, Lin TK, Dagenais SL, Contreras JI, Orringer MB, Glover TW, Beer DG, Lin L.

Cancer Res. 2003 Jul 15;63(14):4136-43.


Identification and characterization of a 19q12 amplicon in esophageal adenocarcinomas reveals cyclin E as the best candidate gene for this amplicon.

Lin L, Prescott MS, Zhu Z, Singh P, Chun SY, Kuick RD, Hanash SM, Orringer MB, Glover TW, Beer DG.

Cancer Res. 2000 Dec 15;60(24):7021-7.


A novel amplicon at 8p22-23 results in overexpression of cathepsin B in esophageal adenocarcinoma.

Hughes SJ, Glover TW, Zhu XX, Kuick R, Thoraval D, Orringer MB, Beer DG, Hanash S.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12410-5.


High frequency of Ki-ras amplification and p53 gene mutations in adenocarcinomas of the human esophagus.

Galiana C, Lozano JC, Bancel B, Nakazawa H, Yamasaki H.

Mol Carcinog. 1995 Dec;14(4):286-93.


Molecular dissection of 17q12 amplicon in upper gastrointestinal adenocarcinomas.

Maqani N, Belkhiri A, Moskaluk C, Knuutila S, Dar AA, El-Rifai W.

Mol Cancer Res. 2006 Jul;4(7):449-55.


ERBB2 amplifications in esophageal adenocarcinoma.

Dahlberg PS, Jacobson BA, Dahal G, Fink JM, Kratzke RA, Maddaus MA, Ferrin LJ.

Ann Thorac Surg. 2004 Nov;78(5):1790-800.


Array comparative genomic hybridization, expression array, and protein analysis of critical regions on chromosome arms 1q, 7q, and 8p in adenocarcinomas of the gastroesophageal junction.

van Dekken H, Tilanus HW, Hop WC, Dinjens WN, Wink JC, Vissers KJ, van Marion R.

Cancer Genet Cytogenet. 2009 Feb;189(1):37-42. doi: 10.1016/j.cancergencyto.2008.08.018.


Gene amplification in esophageal adenocarcinomas and Barrett's with high-grade dysplasia.

Miller CT, Moy JR, Lin L, Schipper M, Normolle D, Brenner DE, Iannettoni MD, Orringer MB, Beer DG.

Clin Cancer Res. 2003 Oct 15;9(13):4819-25.


Identification of ZASC1 encoding a Krüppel-like zinc finger protein as a novel target for 3q26 amplification in esophageal squamous cell carcinomas.

Imoto I, Yuki Y, Sonoda I, Ito T, Shimada Y, Imamura M, Inazawa J.

Cancer Res. 2003 Sep 15;63(18):5691-6.


Multiple forms of genetic instability within a 2-Mb chromosomal segment of 3q26.3-q27 are associated with development of esophageal adenocarcinoma.

Lin L, Wang Z, Prescott MS, van Dekken H, Thomas DG, Giordano TJ, Chang AC, Orringer MB, Gruber SB, Moran JV, Glover TW, Beer DG.

Genes Chromosomes Cancer. 2006 Apr;45(4):319-31.


Involvement of cancer-activating genes on chromosomes 7 and 8 in esophageal (Barrett's) and gastric cardia adenocarcinoma.

Vissers KJ, Riegman PH, Alers JC, Tilanus HW, van Dekken H.

Anticancer Res. 2001 Nov-Dec;21(6A):3813-20.


Identification of target genes within an amplicon at 14q12-q13 in esophageal squamous cell carcinoma.

Yasui K, Imoto I, Fukuda Y, Pimkhaokham A, Yang ZQ, Naruto T, Shimada Y, Nakamura Y, Inazawa J.

Genes Chromosomes Cancer. 2001 Oct;32(2):112-8.


Defining a common region of deletion at 13q21 in human cancers.

Chen C, Brabham WW, Stultz BG, Frierson HF Jr, Barrett JC, Sawyers CL, Isaacs JT, Dong JT.

Genes Chromosomes Cancer. 2001 Aug;31(4):333-44.


Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines.

Yang ZQ, Imoto I, Fukuda Y, Pimkhaokham A, Shimada Y, Imamura M, Sugano S, Nakamura Y, Inazawa J.

Cancer Res. 2000 Sep 1;60(17):4735-9.


New amplified and highly expressed genes discovered in the ERBB2 amplicon in breast cancer by cDNA microarrays.

Kauraniemi P, Bärlund M, Monni O, Kallioniemi A.

Cancer Res. 2001 Nov 15;61(22):8235-40.


Gene amplification in PNETs/medulloblastomas: mapping of a novel amplified gene within the MYCN amplicon.

Frühwald MC, O'Dorisio MS, Rush LJ, Reiter JL, Smiraglia DJ, Wenger G, Costello JF, White PS, Krahe R, Brodeur GM, Plass C.

J Med Genet. 2000 Jul;37(7):501-9.

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