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Items: 1 to 20 of 99

1.
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Amino acid residues in the alpha IIb subunit that are critical for ligand binding to integrin alpha IIbbeta 3 are clustered in the beta-propeller model.

Kamata T, Tieu KK, Irie A, Springer TA, Takada Y.

J Biol Chem. 2001 Nov 23;276(47):44275-83. Epub 2001 Sep 13.

4.

A molecular model of RGD ligands. Antibody D gene segments that direct specificity for the integrin alpha IIb beta 3.

Tomiyama Y, Brojer E, Ruggeri ZM, Shattil SJ, Smiltneck J, Gorski J, Kumar A, Kieber-Emmons T, Kunicki TJ.

J Biol Chem. 1992 Sep 5;267(25):18085-92.

6.

Mapping the binding domains of the alpha(IIb) subunit. A study performed on the activated form of the platelet integrin alpha(IIb)beta(3).

Biris N, Abatzis M, Mitsios JV, Sakarellos-Daitsiotis M, Sakarellos C, Tsoukatos D, Tselepis AD, Michalis L, Sideris D, Konidou G, Soteriadou K, Tsikaris V.

Eur J Biochem. 2003 Sep;270(18):3760-7.

8.

Function-blocking integrin alphavbeta6 monoclonal antibodies: distinct ligand-mimetic and nonligand-mimetic classes.

Weinreb PH, Simon KJ, Rayhorn P, Yang WJ, Leone DR, Dolinski BM, Pearse BR, Yokota Y, Kawakatsu H, Atakilit A, Sheppard D, Violette SM.

J Biol Chem. 2004 Apr 23;279(17):17875-87. Epub 2004 Feb 11.

9.
10.

Ligand binding to integrin alpha(v)beta(3) requires tyrosine 178 in the alpha(v) subunit.

Honda S, Tomiyama Y, Pampori N, Kashiwagi H, Kiyoi T, Kosugi S, Tadokoro S, Kurata Y, Shattil SJ, Matsuzawa Y.

Blood. 2001 Jan 1;97(1):175-82.

PMID:
11133758
11.

Adhesion-induced unclasping of cytoplasmic tails of integrin alpha(IIb)beta3.

Podolnikova NP, O'Toole TE, Haas TA, Lam SC, Fox JE, Ugarova TP.

Biochemistry. 2009 Jan 27;48(3):617-29. doi: 10.1021/bi801751s.

12.
13.

The amino-terminal one-third of alpha IIb defines the ligand recognition specificity of integrin alpha IIb beta 3.

Loftus JC, Halloran CE, Ginsberg MH, Feigen LP, Zablocki JA, Smith JW.

J Biol Chem. 1996 Jan 26;271(4):2033-9.

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A spontaneous mutation of integrin alpha IIb beta 3 (platelet glycoprotein IIb-IIIa) helps define a ligand binding site.

Bajt ML, Ginsberg MH, Frelinger AL 3rd, Berndt MC, Loftus JC.

J Biol Chem. 1992 Feb 25;267(6):3789-94.

17.

Long range propagation of conformational changes in integrin alpha IIb beta 3.

Du X, Gu M, Weisel JW, Nagaswami C, Bennett JS, Bowditch R, Ginsberg MH.

J Biol Chem. 1993 Nov 5;268(31):23087-92. Erratum in: J Biol Chem 1994 Apr 15;269(15):11673.

18.

A cluster of basic amino acid residues in the gamma370-381 sequence of fibrinogen comprises a binding site for platelet integrin alpha(IIb)beta3 (glycoprotein IIb/IIIa).

Podolnikova NP, Gorkun OV, Loreth RM, Yee VC, Lord ST, Ugarova TP.

Biochemistry. 2005 Dec 27;44(51):16920-30.

PMID:
16363805
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