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Items: 1 to 20 of 207

1.

Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors.

Megonigal MD, Cheung NK, Rappaport EF, Nowell PC, Wilson RB, Jones DH, Addya K, Leonard DG, Kushner BH, Williams TM, Lange BJ, Felix CA.

Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2814-9.

2.
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t(3;11) translocation in treatment-related acute myeloid leukemia fuses MLL with the GMPS (GUANOSINE 5' MONOPHOSPHATE SYNTHETASE) gene.

Pegram LD, Megonigal MD, Lange BJ, Nowell PC, Rowley JD, Rappaport EF, Felix CA.

Blood. 2000 Dec 15;96(13):4360-2.

4.

t(11;22)(q23;q11.2) In acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromes.

Megonigal MD, Rappaport EF, Jones DH, Williams TM, Lovett BD, Kelly KM, Lerou PH, Moulton T, Budarf ML, Felix CA.

Proc Natl Acad Sci U S A. 1998 May 26;95(11):6413-8. Erratum in: Proc Natl Acad Sci U S A 1998 Aug 18;95(17):10344.

5.

Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias.

Megonigal MD, Rappaport EF, Jones DH, Kim CS, Nowell PC, Lange BJ, Felix CA.

Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11583-8.

6.

Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation.

Lovett BD, Lo Nigro L, Rappaport EF, Blair IA, Osheroff N, Zheng N, Megonigal MD, Williams WR, Nowell PC, Felix CA.

Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9802-7. Epub 2001 Aug 7.

7.

Panhandle PCR for cDNA: a rapid method for isolation of MLL fusion transcripts involving unknown partner genes.

Megonigal MD, Rappaport EF, Wilson RB, Jones DH, Whitlock JA, Ortega JA, Slater DJ, Nowell PC, Felix CA.

Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9597-602.

8.

Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6.

Raffini LJ, Slater DJ, Rappaport EF, Lo Nigro L, Cheung NK, Biegel JA, Nowell PC, Lange BJ, Felix CA.

Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4568-73.

10.

All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders.

Rowley JD, Reshmi S, Sobulo O, Musvee T, Anastasi J, Raimondi S, Schneider NR, Barredo JC, Cantu ES, Schlegelberger B, Behm F, Doggett NA, Borrow J, Zeleznik-Le N.

Blood. 1997 Jul 15;90(2):535-41.

11.

Secondary leukemias induced by topoisomerase-targeted drugs.

Felix CA.

Biochim Biophys Acta. 1998 Oct 1;1400(1-3):233-55. Review.

PMID:
9748598
12.

Identification of complex genomic breakpoint junctions in the t(9;11) MLL-AF9 fusion gene in acute leukemia.

Super HG, Strissel PL, Sobulo OM, Burian D, Reshmi SC, Roe B, Zeleznik-Le NJ, Diaz MO, Rowley JD.

Genes Chromosomes Cancer. 1997 Oct;20(2):185-95.

PMID:
9331569
13.

Novel MLL-CBP fusion transcript in therapy-related chronic myelomonocytic leukemia with a t(11;16)(q23;p13) chromosome translocation.

Satake N, Ishida Y, Otoh Y, Hinohara S, Kobayashi H, Sakashita A, Maseki N, Kaneko Y.

Genes Chromosomes Cancer. 1997 Sep;20(1):60-3.

PMID:
9290955
14.

Panhandle polymerase chain reaction amplifies MLL genomic translocation breakpoint involving unknown partner gene.

Felix CA, Kim CS, Megonigal MD, Slater DJ, Jones DH, Spinner NB, Stump T, Hosler MR, Nowell PC, Lange BJ, Rappaport EF.

Blood. 1997 Dec 15;90(12):4679-86.

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16.

A novel chromosomal inversion at 11q23 in infant acute myeloid leukemia fuses MLL to CALM, a gene that encodes a clathrin assembly protein.

Wechsler DS, Engstrom LD, Alexander BM, Motto DG, Roulston D.

Genes Chromosomes Cancer. 2003 Jan;36(1):26-36.

17.

Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome.

Robinson BW, Cheung NK, Kolaris CP, Jhanwar SC, Choi JK, Osheroff N, Felix CA.

Blood. 2008 Apr 1;111(7):3802-12. doi: 10.1182/blood-2007-07-096065. Epub 2008 Jan 14.

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Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: almost identical MLL breakpoints in therapy-related AML after treatment without etoposides.

Langer T, Metzler M, Reinhardt D, Viehmann S, Borkhardt A, Reichel M, Stanulla M, Schrappe M, Creutzig U, Ritter J, Leis T, Jacobs U, Harbott J, Beck JD, Rascher W, Repp R.

Genes Chromosomes Cancer. 2003 Apr;36(4):393-401.

PMID:
12619163

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