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Items: 1 to 20 of 98

1.

Defective Jak-STAT signal transduction pathway in melanoma cells resistant to growth inhibition by interferon-alpha.

Pansky A, Hildebrand P, Fasler-Kan E, Baselgia L, Ketterer S, Beglinger C, Heim MH.

Int J Cancer. 2000 Mar 1;85(5):720-5.

2.

The JAK/STAT pathway is not sufficient to sustain the antiproliferative response in an interferon-resistant human melanoma cell line.

Jackson DP, Watling D, Rogers NC, Banks RE, Kerr IM, Selby PJ, Patel PM.

Melanoma Res. 2003 Jun;13(3):219-29.

PMID:
12777975
3.

Configuration of the interferon-alpha/beta receptor complex determines the context of the biological response.

Ghislain J, Sussman G, Goelz S, Ling LE, Fish EN.

J Biol Chem. 1995 Sep 15;270(37):21785-92.

4.

Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma.

Wong LH, Krauer KG, Hatzinisiriou I, Estcourt MJ, Hersey P, Tam ND, Edmondson S, Devenish RJ, Ralph SJ.

J Biol Chem. 1997 Nov 7;272(45):28779-85.

5.

Growth effects of alpha-interferon but not of bombesin or angiotensin II are mediated by activation of STAT proteins.

Pansky A, Hildebrand P, Heim MH, Eberhard M, Kissel T, Beglinger C.

Eur J Clin Invest. 1998 May;28(5):398-406.

PMID:
9650014
7.

The neutralization of type I IFN biologic actions by anti-IFNAR-2 monoclonal antibodies is not entirely due to inhibition of Jak-Stat tyrosine phosphorylation.

Novick D, Nabioullin RR, Ragsdale W, McKenna S, Weiser W, Garone L, Burkins C, Kim SH, Rubinstein M, Tepper MA, Arulanandam AR.

J Interferon Cytokine Res. 2000 Nov;20(11):971-82.

PMID:
11096454
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Vanadate facilitates interferon alpha-mediated apoptosis that is dependent on the Jak/Stat pathway.

Gamero AM, Larner AC.

J Biol Chem. 2001 Apr 27;276(17):13547-53. Epub 2001 Jan 19.

12.

Aberrant activation of JAK/STAT pathway components in response to G-CSF, interferon-alpha/beta and interferon-gamma in NFS-60 cells.

Novak U, Ward AC, Hertzog PJ, Hamilton JA, Paradiso L.

Growth Factors. 1996;13(3-4):251-60.

PMID:
8919032
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Expression of hepatitis c virus proteins inhibits interferon alpha signaling in the liver of transgenic mice.

Blindenbacher A, Duong FH, Hunziker L, Stutvoet ST, Wang X, Terracciano L, Moradpour D, Blum HE, Alonzi T, Tripodi M, La Monica N, Heim MH.

Gastroenterology. 2003 May;124(5):1465-75.

PMID:
12730885
17.

Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase.

Colamonici O, Yan H, Domanski P, Handa R, Smalley D, Mullersman J, Witte M, Krishnan K, Krolewski J.

Mol Cell Biol. 1994 Dec;14(12):8133-42.

18.

The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha.

Li S, Labrecque S, Gauzzi MC, Cuddihy AR, Wong AH, Pellegrini S, Matlashewski GJ, Koromilas AE.

Oncogene. 1999 Oct 14;18(42):5727-37.

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