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Items: 1 to 20 of 112

1.

Acute cigarette smoke-induced connective tissue breakdown is mediated by neutrophils and prevented by alpha1-antitrypsin.

Dhami R, Gilks B, Xie C, Zay K, Wright JL, Churg A.

Am J Respir Cell Mol Biol. 2000 Feb;22(2):244-52.

PMID:
10657946
2.

Acute cigarette smoke-induced connective tissue breakdown requires both neutrophils and macrophage metalloelastase in mice.

Churg A, Zay K, Shay S, Xie C, Shapiro SD, Hendricks R, Wright JL.

Am J Respir Cell Mol Biol. 2002 Sep;27(3):368-74.

PMID:
12204900
3.
4.

Role of neutrophils and alpha1-antitrypsin in coal- and silica-induced connective tissue breakdown.

Zay K, Loo S, Xie C, Devine DV, Wright J, Churg A.

Am J Physiol. 1999 Feb;276(2 Pt 1):L269-79.

5.

Synthetic serine elastase inhibitor reduces cigarette smoke-induced emphysema in guinea pigs.

Wright JL, Farmer SG, Churg A.

Am J Respir Crit Care Med. 2002 Oct 1;166(7):954-60.

PMID:
12359653
6.

alpha-1-Antitrypsin ameliorates cigarette smoke-induced emphysema in the mouse.

Churg A, Wang RD, Xie C, Wright JL.

Am J Respir Crit Care Med. 2003 Jul 15;168(2):199-207. Epub 2003 Apr 10.

PMID:
12689849
7.

Tumor necrosis factor-alpha is central to acute cigarette smoke-induced inflammation and connective tissue breakdown.

Churg A, Dai J, Tai H, Xie C, Wright JL.

Am J Respir Crit Care Med. 2002 Sep 15;166(6):849-54.

PMID:
12231496
8.

The role of interleukin-1beta in murine cigarette smoke-induced emphysema and small airway remodeling.

Churg A, Zhou S, Wang X, Wang R, Wright JL.

Am J Respir Cell Mol Biol. 2009 Apr;40(4):482-90. doi: 10.1165/rcmb.2008-0038OC. Epub 2008 Oct 17.

PMID:
18931327
9.
10.

Alpha-1-antitrypsin and a broad spectrum metalloprotease inhibitor, RS113456, have similar acute anti-inflammatory effects.

Churg A, Dai J, Zay K, Karsan A, Hendricks R, Yee C, Martin R, MacKenzie R, Xie C, Zhang L, Shapiro S, Wright JL.

Lab Invest. 2001 Aug;81(8):1119-31.

PMID:
11502863
11.

Inhibition of interleukin-1beta reduces mouse lung inflammation induced by exposure to cigarette smoke.

Castro P, Legora-Machado A, Cardilo-Reis L, Valença S, Porto LC, Walker C, Zuany-Amorim C, Koatz VL.

Eur J Pharmacol. 2004 Sep 13;498(1-3):279-86.

PMID:
15364006
12.

Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown.

Braber S, Koelink PJ, Henricks PA, Jackson PL, Nijkamp FP, Garssen J, Kraneveld AD, Blalock JE, Folkerts G.

Am J Physiol Lung Cell Mol Physiol. 2011 Feb;300(2):L255-65. doi: 10.1152/ajplung.00304.2010. Epub 2010 Nov 26.

13.

Mineral dusts cause elastin and collagen breakdown in the rat lung: a potential mechanism of dust-induced emphysema.

Li K, Keeling B, Churg A.

Am J Respir Crit Care Med. 1996 Feb;153(2):644-9.

PMID:
8564112
14.

Acute cigarette smoke exposure in dogs: the inflammatory response.

Abrams WR, Kucich U, Kimbel P, Glass M, Weinbaum G.

Exp Lung Res. 1988;14(4):459-75.

PMID:
3208713
15.
16.

Mechanisms of cigarette smoke induced increased airspace permeability.

Li XY, Rahman I, Donaldson K, MacNee W.

Thorax. 1996 May;51(5):465-71.

17.

Tumor necrosis factor-alpha drives 70% of cigarette smoke-induced emphysema in the mouse.

Churg A, Wang RD, Tai H, Wang X, Xie C, Wright JL.

Am J Respir Crit Care Med. 2004 Sep 1;170(5):492-8. Epub 2004 Jun 7.

PMID:
15184206
18.

Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release.

Churg A, Wang RD, Tai H, Wang X, Xie C, Dai J, Shapiro SD, Wright JL.

Am J Respir Crit Care Med. 2003 Apr 15;167(8):1083-9. Epub 2003 Jan 9.

PMID:
12522030
19.

Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice.

Sato A, Hoshino Y, Hara T, Muro S, Nakamura H, Mishima M, Yodoi J.

J Pharmacol Exp Ther. 2008 May;325(2):380-8. doi: 10.1124/jpet.107.134007. Epub 2008 Feb 6.

20.

Mechanisms of mineral dust-induced emphysema.

Churg A, Zay K, Li K.

Environ Health Perspect. 1997 Sep;105 Suppl 5:1215-8.

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